Protein Alignment ACTR1A and Arp6

DIOPT Version :9

• Sequence 1: NP_005727.1
• Gene: ACTR1A / 10121
• HGNCID: 167
• Length: 376
• Species: Homo sapiens
• Sequence 2: NP_511165.1
• Gene: Arp6 / 32514
• FlyBaseID: FBgn0011741
• Length: 398
• Species: Drosophila melanogaster
• Alignment Length: 408
• Identity: 107/408 - (26%)
• Similarity: 191/408 - (46%)
• Gaps: 50/408 - (12%)

Human     7 IANQPVVIDNGSGVIKAGFAGDQIPKYCFPNYVGRPKHVRVMAGALEGDIFIGPKAEEHRGLLSI 71
            :||..||:|||:...|.|.|....| :..||.:.:.|..|..|       |:|.:.:|.|...::
  Fly     1 MANAVVVLDNGAHTAKVGLANQDEP-HVVPNCIMKAKSERRRA-------FVGNQIDECRDTSAL 57

Human    72 RY--PMEHGIVKDWNDMERIWQYVYSKDQLQTFSEEHPVLLTEAPLNPRKNRERAAEVFFETFNV 134
            .|  ..:.|.:.:|:..:.:|.|::|||.:....|...:::||..:|.:..:|...|:.||.:.|
  Fly    58 YYILAFQRGYLLNWHTQKTVWDYIFSKDGIGCSLENRNIVITEPQMNFQSIQEATLEILFEEYKV 122

Human   135 PALFISMQAVLSLY-----ATGRTT-----GVVLDSGDGVTHAVPIYEGFAMPHSIMRIDIAGRD 189
            ..::.:..|.|:.:     :..|||     .:::|.|...||.||...|..:...|.|||:.|:.
  Fly   123 DGVYKTTAADLAAFNYVADSEERTTMESLNCIIIDVGYSFTHVVPFVLGRRVLQGIRRIDMGGKA 187

Human   190 VSRFLRLYLRKEGYDFHSSSEFEIVKAIKERACYLSINPQK-------DETLETEKAQYYLPDGS 247
            ::..|:..:...  ..:...|..:|..|||..|:::.:.::       :|........|.|||.:
  Fly   188 LTNQLKELISYR--HLNVMDESHVVNQIKEDVCFVAEDFKQAMQVHYSEEKRREVTVDYVLPDFT 250

Human   248 TIEIG---------------------PSRFRAPELLFRPDLIGEESEGIHEVLVFAIQKSDMDLR 291
            |::.|                     ..||..|||||.|..||.:..||.|.:...::....:..
  Fly   251 TVKRGYVRVPGKPREDEEQQQMVSLCNERFTVPELLFNPSDIGVQQVGIPEAVADCLKACPWEAH 315

Human   292 RTLFSNIVLSGGSTLFKGFGDRLLSEVKKLAPKDVKIRISAPQERLYSTWIGGSILASLDTFKKM 356
            |.|..||::.|||..|.||..||..:::.|.|.|:::.:..|::.:...|.||..:|:...|::.
  Fly   316 RELLLNILIVGGSAQFPGFLPRLKRDLRALVPDDLEVSLICPEDPVRYAWYGGKEVATSPNFEEF 380

Human   357 WVSKKEYEEDGARSIHRK 374
            ..::.:|||.|.:.|:::
  Fly   381 VYTQDDYEEYGFQGINQR 398

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ACTR1A	NP_005727.1	NBD_sugar-kinase_HSP70_actin	5..376	CDD:418402	107/408 (26%)
Arp6	NP_511165.1	ACTIN	3..398	CDD:214592	106/404 (26%)
		COG5277	6..391	CDD:227602	103/394 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D649708at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.920