DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment ACTR1B and Act88F

DIOPT Version :9

Sequence 1:NP_005726.1 Gene:ACTR1B / 10120 HGNCID:168 Length:376 Species:Homo sapiens
Sequence 2:NP_524367.1 Gene:Act88F / 41885 FlyBaseID:FBgn0000047 Length:376 Species:Drosophila melanogaster


Alignment Length:370 Identity:205/370 - (55%)
Similarity:278/370 - (75%) Gaps:7/370 - (1%)


- Green bases have known domain annotations that are detailed below.


Human    12 VVIDNGSGVIKAGFAGDQIPKYCFPNYVGRPKHMRVMAGALEGDLFIGPKAEEHRGLLTIRYPME 76
            :|||||||:.|||||||..|:..||:.||||:|..||.|..:.|.::|.:|:..||:||::||:|
  Fly     9 LVIDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIE 73

Human    77 HGVVRDWNDMERIWQYVYSKDQLQTFSEEHPVLLTEAPLNPSKNREKAAEVFFETFNVPALFISM 141
            ||::.:|:|||:||.:.: .::|:...||||||||||||||..||||..::.|||||.||:::::
  Fly    74 HGIITNWDDMEKIWHHTF-YNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNSPAMYVAI 137

Human   142 QAVLSLYATGRTTGVVLDSGDGVTHAVPIYEGFAMPHSIMRVDIAGRDVSRYLRLLLRKEGVDFH 206
            ||||||||:|||||:||||||||:|.||||||||:||:|:|:|:||||::.||..:|.:.|..|.
  Fly   138 QAVLSLYASGRTTGIVLDSGDGVSHTVPIYEGFALPHAILRLDLAGRDLTDYLMKILTERGYSFT 202

Human   207 TSAEFEVVRTIKERACYLSINPQKDEA-----LETEKVQYTLPDGSTLDVGPARFRAPELLFQPD 266
            |:||.|:||.|||:.||::::.:::.|     ...|| .|.||||..:.:|..|||.||.||||.
  Fly   203 TTAEREIVRDIKEKLCYVALDFEQEMATAAASTSLEK-SYELPDGQVITIGNERFRCPEALFQPS 266

Human   267 LVGDESEGLHEVVAFAIHKSDMDLRRTLFANIVLSGGSTLFKGFGDRLLSEVKKLAPKDIKIKIS 331
            .:|.||.|:||.|..:|.|.|:|:|:.|:||.|||||:|::.|..||:..|:..|||..|||||.
  Fly   267 FLGMESCGIHETVYNSIMKCDVDIRKDLYANSVLSGGTTMYPGIADRMQKEITALAPSTIKIKII 331

Human   332 APQERLYSTWIGGSILASLDTFKKMWVSKKEYEEDGSRAIHRKTF 376
            ||.||.||.||||||||||.||::||:||:||:|.|...:|||.|
  Fly   332 APPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPGIVHRKCF 376

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
ACTR1BNP_005726.1 NBD_sugar-kinase_HSP70_actin 5..376 CDD:418402 204/368 (55%)
Act88FNP_524367.1 PTZ00281 1..376 CDD:173506 204/368 (55%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG5277
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D649708at2759
OrthoFinder 1 1.000 - - FOG0000057
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
43.820

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