Protein Alignment OPN1MW3 and dop-4

DIOPT Version :9

• Sequence 1: NP_001316996.1
• Gene: OPN1MW3 / 101060233
• HGNCID: 51831
• Length: 364
• Species: Homo sapiens
• Sequence 2: NP_508238.2
• Gene: dop-4 / 183715
• WormBaseID: WBGene00016872
• Length: 517
• Species: Caenorhabditis elegans
• Alignment Length: 525
• Identity: 96/525 - (18%)
• Similarity: 168/525 - (32%)
• Gaps: 210/525 - (40%)

Human    12 GRHP--QDSYEDSTQSSIFTYTNSNSTRGPFEGPNYHIAPRWVYHLTSVWMIFVVIASVFTNGLV 74
            |..|  :|.|...|.|   ..|.:::|....|.|   .|..|.:.|.::.:..:.:.:|..|.||
 Worm     5 GSDPNAEDLYITMTPS---VSTENDTTVWATEEP---AAIVWRHPLLAIALFSICLLTVAGNCLV 63

Human    75 LAATMKFKKLRHPLNWILVNLAVADLAETVIASTISVVNQVYGY-FVLGHPMCVLEGYTVSLCGI 138
            :.|....|.||:|..:::::||:|||...||...::.:.::..: ::.|..||.:......|...
 Worm    64 VIAVCTKKYLRNPTGYLIISLAIADLIVGVIVMPMNSLFEIANHTWLFGLMMCDVFHAMDILAST 128

Human   139 TGLWSLAIISWERWMVVCKPFG-NVRFDAKLAIVGIAFSWIWAAVWTAPPIFGWSRYWPHGL--K 200
            ..:|:|.:||.:|:|....|.| ..:...:..::.|...|:.:|:.:.|.|..|....||..  :
 Worm   129 ASIWNLCVISLDRYMAGQDPIGYRDKVSKRRILMAILSVWVLSAILSFPGIIWWRTSSPHLYEDQ 193

Human   201 TSCGPDVFSGS----SYPGVQSYMIVLMVTCCITPLSIIVLCYLQVW-----------LAIRAVA 250
            :.|   :|:.|    |:..:.|:.|         ||.:|:..|.:|:           :.|:.|:
 Worm   194 SQC---LFTDSKMYVSFSSLVSFYI---------PLFLILFAYGKVYIIATRHSKGMRMGIKTVS 246

Human   251 -------KQQKESESTQKAEKEVT----------------------------------------- 267
                   |...|:||...:|.|.|
 Worm   247 IKKRNGKKSNTETESILSSENEPTLRIHFGRGKQSSSSLRNSRFHARESTRLLLKQVSCKSLNDR 311

Human   268 ----------------------------------------------------------------- 267
                                                                             
 Worm   312 GEHNNNNTVRQPLLRGTEGCHSDSISRSSQRNFRGRNVTIGSNCSSTLLQVDQPDRMSLSSNSQM 376

Human   268 -------------------------------RMVVVMVLAFCFCWGPYAFFACFAAANPGYPFHP 301
                                           |.:.::|.||..||.|:            :.|.|
 Worm   377 VMTSPLSTRRKLNVREKSRQMMRYVHEQRAARTLSIVVGAFILCWTPF------------FVFTP 429

Human   302 LMAALPAFFAKSATIY-------------NPVIYVFMNRQFRNCILQLFGKKVDDGSELSSASKT 353
            |.|...:.|:...||:             ||:||...:|.||....|:.  ......::.:|.||
 Worm   430 LTAFCESCFSNKETIFTFVTWAGHLNSMLNPLIYSRFSRDFRRAFKQIL--TCQRQQKVKTAFKT 492

Human   354 EVSSV 358
            .:|.|
 Worm   493 PLSLV 497

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
OPN1MW3	NP_001316996.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..23		4/12 (33%)
		Required for 11-cis-retinal regeneration. /evidence=ECO:0000250|UniProtKB:P04001	17..43		7/25 (28%)
		7tm_4	61..>178	CDD:304433	29/118 (25%)
		7tm_1	71..322	CDD:278431	71/426 (17%)
dop-4	NP_508238.2	7tm_4	53..>245	CDD:304433	48/203 (24%)
		7tm_1	59..463	CDD:278431	71/427 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910