DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment OPN1MW3 and frpr-2

DIOPT Version :9

Sequence 1:NP_001316996.1 Gene:OPN1MW3 / 101060233 HGNCID:51831 Length:364 Species:Homo sapiens
Sequence 2:NP_510154.3 Gene:frpr-2 / 182268 WormBaseID:WBGene00007346 Length:353 Species:Caenorhabditis elegans


Alignment Length:197 Identity:38/197 - (19%)
Similarity:69/197 - (35%) Gaps:54/197 - (27%)


- Green bases have known domain annotations that are detailed below.


Human    57 SVW---MIFVVIASVFTNGLVLAATMKFKKLRHPLNWILVNLAVADLAETVIASTISVVNQVYGY 118
            |.|   ::.:|:.||....:|....::..:..||.|:.|..|...::.          |::.|  
 Worm   141 STWAPRVLALVVISVAGYNIVQFGDLQAIECLHPDNYTLFELCPTEMR----------VSETY-- 193

Human   119 FVLGHPMCVLEGYTVSLCGITGLWSLAIISWERWMVVCKPFGNVRFDAKLAIVGIAFSWIWAAVW 183
                  :.|.:||..:|       |:|.:          ||..:.|.....||.:...       
 Worm   194 ------VIVYKGYLYAL-------SMAFL----------PFVLLTFLTVSIIVMLRRK------- 228

Human   184 TAPPIFGWSRYWPHGLKTSCGPDVFSGSSYPGVQSYMIVLMVTCCITPLSIIVLCYLQVWLAIRA 248
                  ..:.:.....|..|..|   |.:.|.|...:::|.:.|.:|.|.:.|...|:..:|...
 Worm   229 ------NETMHMDKAEKEECEDD---GGNNPVVLLLVVLLFLCCNLTSLLVNVFEMLKFNMAFET 284

Human   249 VA 250
            .|
 Worm   285 EA 286

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
OPN1MW3NP_001316996.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..23
Required for 11-cis-retinal regeneration. /evidence=ECO:0000250|UniProtKB:P04001 17..43
7tm_4 61..>178 CDD:304433 22/116 (19%)
7tm_1 71..322 CDD:278431 33/180 (18%)
frpr-2NP_510154.3 7tmA_FMRFamide_R-like 29..318 CDD:320109 38/197 (19%)
TM helix 1 30..53 CDD:320109
TM helix 2 60..82 CDD:320109
TM helix 3 102..124 CDD:320109
TM helix 4 146..162 CDD:320109 3/15 (20%)
TM helix 5 196..219 CDD:320109 9/39 (23%)
TM helix 6 247..272 CDD:320109 6/24 (25%)
TM helix 7 286..311 CDD:320109 1/1 (100%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

Return to query results.
Submit another query.