DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment rnf167 and SPAC57A7.09

DIOPT Version :9

Sequence 1:	XP_005165694.2	Gene:	rnf167 / 101055497	ZFINID:	ZDB-GENE-110126-2	Length:	401	Species:	Danio rerio
Sequence 2:	NP_593372.1	Gene:	SPAC57A7.09 / 2542187	PomBaseID:	SPAC57A7.09	Length:	372	Species:	Schizosaccharomyces pombe

Alignment Length:	320	Identity:	72/320 - (22%)
Similarity:	129/320 - (40%)	Gaps:	66/320 - (20%)

- Green bases have known domain annotations that are detailed below.

Zfish    26 QAYIYAHYSN--MTSMLFEDLPALF--------------GSALPKDGLMGVLIEARPQNACTPID 74
            ||....|::|  .|:::...||:.|              .|...::.::...||...|.:   ..
pombe    60 QAVFGKHFTNASATTVINLYLPSNFQEDMSGCPNRNDTDASYFYENDIIDYDIEYIEQKS---YS 121

Zfish    75 PPPASPTPADPNSTTK-----YIVLIRRYDCNFDVKVYHAQQAGYSAAIVHNMYSNSLLNMGY-- 132
            ..|::....|....:|     ..:|::|..|.:..|...||:.|:...||.:..|.|...:.|
pombe   122 SKPSARVQKDDGGESKDEAILDFLLVQRGKCTYFDKALEAQRLGFKGVIVGDNRSPSSFRLHYMV 186

Zfish   133 -SNETIAEEISIPSVFTS-----FFASQMLHKIIPEKGAYVVLKPE----FSFPLSYYLIPFTGV 187
             .::....::.|||:|.|     ...|.:||........|.  |||    ..:|   :|:.|:..
pombe   187 APDKVDESKVHIPSLFVSTSSYNLLWSDLLHSYRQPLKLYA--KPEELGDMFWP---FLLCFSPS 246

Zfish   188 VCMIIIV--MVIIMIVRCVQHRKRLRK-------NRLSKEQL--------------KKIPI-HKF 228
            :.|:|.|  :.|...:|..:.:.:.|:       ..:|:|..              :.:|: .:.
pombe   247 IIMLITVQALAIRKFIRTYRTKSKTRRFIEDLPSRTISREGFYSEEEEIENSTQNGELVPLMDES 311

Zfish   229 NKGDSYDV-CAICLDEYEEGDKLRVLPCSHAYHSRCVDPWLTQTKKTCPVCKQRVTRPNP 287
            .:..::.| |.|||:.:.:|||:..|||.|.:|..|:..|:...:..||.|...|..|.|
pombe   312 TRRATFGVECVICLESFTKGDKVVALPCKHEFHRPCIAKWIVDYRHACPTCNTEVPPPKP 371

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rnf167	XP_005165694.2	PA_C_RZF_like	14..177	CDD:239038	39/183 (21%)
		RING-H2_RNF167	235..280	CDD:319711	18/45 (40%)
		RING-H2 finger (C3H2C3-type)	237..278	CDD:319711	16/40 (40%)
SPAC57A7.09	NP_593372.1	COG5540	1..369	CDD:227827	70/316 (22%)
		Peptidases_S8_S53	<144..211	CDD:299169	17/66 (26%)
		zf-RING_2	320..362	CDD:290367	16/41 (39%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	70	1.000	Inparanoid score	I2160
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm34392
orthoMCL	1	0.900	-	-		OOG6_103040
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X670
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.860