DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment rnf167 and rnf167

DIOPT Version :9

Sequence 1:	XP_005165694.2	Gene:	rnf167 / 101055497	ZFINID:	ZDB-GENE-110126-2	Length:	401	Species:	Danio rerio
Sequence 2:	XP_031755442.1	Gene:	rnf167 / 100379947	XenbaseID:	XB-GENE-5944055	Length:	346	Species:	Xenopus tropicalis

Alignment Length:	397	Identity:	189/397 - (47%)
Similarity:	239/397 - (60%)	Gaps:	67/397 - (16%)

- Green bases have known domain annotations that are detailed below.

Zfish     1 MVCLGSPLAVSVLL----IIFCTLVPSPGQAYIYAHYSNMTSMLFEDLPALFGSALPKDGLMGVL 61
            |..:|| |:.|.:|    .:.|.|..:....|.|:........:|:|||||||.:||.||:.|.|
Frog     1 MFVMGS-LSHSHVLGAFTFLLCALPTAHSMIYAYSDVRTREPQMFDDLPALFGPSLPTDGMKGSL 64

Zfish    62 IEARPQNACTPIDPPPASPTPADPNSTTKYIVLIRRYDCNFDVKVYHAQQAGYSAAIVHNMYSNS 126
            ::|.|:||||||.|||.       ::.|.:||||||.|||||.||.|||.|||:||||||:.::.
Frog    65 VQAVPENACTPILPPPT-------DNGTSFIVLIRRNDCNFDTKVLHAQLAGYNAAIVHNVGADL 122

Zfish   127 LLNMGYSNETIAEEISIPSVFTSFFASQ-MLHKIIPEKGAYVVLKPEFSFPLSYYLIPFTGVVCM 190
            ||.||:::|:|..:|.||||||...:.: :|........:::.|.|::.|.|.||||||..||.:
Frog   123 LLRMGWNDESIRRQIRIPSVFTGESSGRSLLANFSYYNNSHIYLVPDYYFSLGYYLIPFIVVVSV 187

Zfish   191 IIIVMVIIMIVRCVQHRKRLRKNRLSKEQLKKIPIHKFNKGDSYDVCAICLDEYEEGDKLRVLPC 255
            :|:||.|:|:|||.|:|||:|:||||||||||||||||.|||.||||||||:|||||||||||||
Frog   188 VIVVMCIVMVVRCAQYRKRMRRNRLSKEQLKKIPIHKFKKGDDYDVCAICLEEYEEGDKLRVLPC 252

Zfish   256 SHAYHSRCVDPWLTQTKKTCPVCKQRVTRPNPEYSESSDSDEEAG------PHDAEEEDERTPLL 314
            |||||..|||||||:|||:|||||.||.|      ..||||.:.|      ....|.::||||||
Frog   253 SHAYHCSCVDPWLTKTKKSCPVCKNRVFR------SDSDSDSDTGGPVANDDQGEESDNERTPLL 311

Zfish   315 RPSNPGSPASSSPPPSYSSTVASEPATVTTAAQCLPHTPQHDAPLLANDEYYSPIEDSDDEGSED 379
            |||           ||:.|...|..|                               ...|..|:
Frog   312 RPS-----------PSFGSMAESPRA-------------------------------GQQEEEEE 334

Zfish   380 EEEGHAS 386
            |||..|:
Frog   335 EEEAVAA 341

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rnf167	XP_005165694.2	PA_C_RZF_like	14..177	CDD:239038	73/167 (44%)
		RING-H2_RNF167	235..280	CDD:319711	39/44 (89%)
		RING-H2 finger (C3H2C3-type)	237..278	CDD:319711	35/40 (88%)
rnf167	XP_031755442.1	PA_C_RZF_like	17..174	CDD:239038	71/157 (45%)
rnf167	XP_031755442.1	RING_Ubox	232..277	CDD:418438	38/44 (86%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	104	1.000	Domainoid score	I25057
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H41046
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1487241at2759
OrthoFinder	1	1.000	-	-		FOG0001489
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR22765
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X670
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	7.110