Protein Alignment TSPAN1 and Tsp5D

DIOPT Version :9

• Sequence 1: XP_011538762.1
• Gene: TSPAN1 / 10103
• HGNCID: 20657
• Length: 258
• Species: Homo sapiens
• Sequence 2: NP_001259266.1
• Gene: Tsp5D / 31540
• FlyBaseID: FBgn0029837
• Length: 287
• Species: Drosophila melanogaster
• Alignment Length: 266
• Identity: 54/266 - (20%)
• Similarity: 104/266 - (39%)
• Gaps: 68/266 - (25%)

Human     4 FSFIKTMMILFNLLIFLCGAALLAVGIWVSIDGASFLKIF---GPLSSSAMQFVNVGYFLIAAGV 65
            ::.|:......|::::||..|.|..|:|:.:..|.:..:.   ..||:..: |:.:|    ..|
  Fly     6 YTCIRRTFCWLNIILWLCSCAFLGAGLWLRLSYAGYATLLPQHAGLSADTI-FMGIG----GTG- 64

Human    66 VVFALGFLGCYGAKTESKCALVTFFFILLLIFIAEVAAAVVALVY-----TTMAEHFLTLLVVPA 125
              |.:.|.||.||..:|:|.||.:|.:::::|::|.....:|.::     .|:|.....     .
  Fly    65 --FVVSFFGCCGAWVQSRCLLVLYFMLIVMLFMSEFLVGSIAFLFRGGLGRTLANELRF-----G 122

Human   126 IKKDYGSQE-------DFTQVWNTTMKGLKCCGFTNYTDFEDSPYFKENSAFPPFCCNDNVTNTA 183
            |::.|.|.:       ....:|::..:..:|||.::|.|:.|...:......|..||
  Fly   123 IERHYNSSDRGSLVAPSVASIWDSVQQSFECCGVSSYEDWYDIQSWPGRRWVPESCC-------- 179

Human   184 NETCTKQKAHDQKV--------------------------EGCFNQLLYDIRTNAVTVGGVAAGI 222
                  :..:||:.                          :||.:.|..........||.|..||
  Fly   180 ------RTLYDQRQVLTEGSGDGMMRPDCGRSENPSLWWDKGCAHSLQSWFTGQLNVVGAVGLGI 238

Human   223 GGLEFF 228
            ..::.|
  Fly   239 AFVQLF 244

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TSPAN1	XP_011538762.1	Tetraspannin	7..214	CDD:278750	48/247 (19%)
		uroplakin_I_like_LEL	110..212	CDD:239409	20/139 (14%)
Tsp5D	NP_001259266.1	Tetraspannin	8..256	CDD:278750	54/264 (20%)
		NET-5_like_LEL	105..228	CDD:239418	20/141 (14%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3882
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X124
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.810