Protein Alignment TSPAN2 and Tsp42Er

DIOPT Version :9

• Sequence 1: NP_005716.2
• Gene: TSPAN2 / 10100
• HGNCID: 20659
• Length: 221
• Species: Homo sapiens
• Sequence 2: NP_523644.1
• Gene: Tsp42Er / 35629
• FlyBaseID: FBgn0033139
• Length: 211
• Species: Drosophila melanogaster
• Alignment Length: 219
• Identity: 57/219 - (26%)
• Similarity: 99/219 - (45%)
• Gaps: 35/219 - (15%)

Human    11 IKYLLLGFNLLFWLAGSAVIAFGLWFRFGGAIKELSSEDKSPEYFYVGLYVLVGAGALMMAVGFF 75
            |:||...||.|..:.|.|.|...:.     ||.:::.:|:    ..:|||:.|  |:::..:.||
  Fly     8 IRYLAFLFNFLCAVLGIATIVVNVI-----AIDQIAPKDQ----LILGLYIAV--GSIVFLLSFF 61

Human    76 GCCGAMRESQCVLGSFFTCLLVIFAAEVTTGVFAFIGKGVAIRHVQTMYEEAYNDYLKDR-GKGN 139
            ||.||::||.||..::.|.:||:....:.. :|.|          :..:||.....||.. .|..
  Fly    62 GCFGAIKESICVTWAYATSMLVMLIVSIVM-LFVF----------RMHFEEDSITKLKQAFAKQT 115

Human   140 GT---LITFHSTFQCCG----KESSE---QVQPTC--PKELLGHKNCIDEIETIISVKLQLIGIV 192
            .|   :..:.:.:||||    |:..:   .|..:|  ..:......|:.::||.....|:...||
  Fly   116 NTFDAMAEYQTQYQCCGIYKLKDYGDAYITVPSSCYDQNDTPYRDGCLAKMETQYEELLKGPKIV 180

Human   193 GIGIAGLTIFGMIFSMVLCCAIRN 216
            |..:..:.|....||.::..::||
  Fly   181 GWMLMVIEIGAFTFSTIMGVSLRN 204

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TSPAN2	NP_005716.2	Tetraspannin	11..210	CDD:395265	55/211 (26%)
Tsp42Er	NP_523644.1	Tetraspannin	8..195	CDD:278750	53/208 (25%)
		tetraspanin_LEL	93..174	CDD:239401	18/90 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3882
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810