Protein Alignment TSPAN5 and Tsp86D

DIOPT Version :9

• Sequence 1: NP_005714.2
• Gene: TSPAN5 / 10098
• HGNCID: 17753
• Length: 268
• Species: Homo sapiens
• Sequence 2: NP_001262468.1
• Gene: Tsp86D / 41310
• FlyBaseID: FBgn0037848
• Length: 316
• Species: Drosophila melanogaster
• Alignment Length: 285
• Identity: 112/285 - (39%)
• Similarity: 166/285 - (58%)
• Gaps: 22/285 - (7%)

Human     3 GKHYKGPE----------VSCCIKYFIFGFNVIFWFLGITFLGIGLWAWNEKGVLSN----ISSI 53
            |.:|..|.          ||.|:||.||..|.:||..|...|.||::|:.:|.:..|    :.:|
  Fly     9 GGNYMHPRISTYPHHFSYVSSCVKYMIFLLNFLFWLFGGLLLAIGVYAFMDKLMDGNGWLRLDTI 73

Human    54 TDLGGFDPVWLFLVVGGVMFILGFAGCIGALRENTFLLKFFSVFLGIIFFLELTAGVLAFVFKDW 118
            .|: .|:...:.::.|.::|.:.||||:|||||||:|||.:|:.|.:.|.||::..::.|||..:
  Fly    74 YDV-IFNISLVMIIAGVIVFTVSFAGCLGALRENTWLLKLYSMCLLLFFILEMSLAIICFVFPQY 137

Human   119 IKDQL-YFFINNNIRAYRDDIDLQNLIDFTQEYWQCCGA--FGADDWNLNIYFNCTDSNASRERC 180
            :...| |.|.:..|.:||||.||||.|||.|:.:.|||.  .|..||:.|.||||  |:.|.|||
  Fly   138 MNSFLEYQFTDKIIHSYRDDSDLQNFIDFAQQEFNCCGLSNAGYQDWSKNEYFNC--SSPSVERC 200

Human   181 GVPFSCC--TKDPAEDVINTQCGYDARQKPEVDQQIVIYTKGCVPQFEKWLQDNLTIVAGIFIGI 243
            |||:|||  ..|.:..::|..|||..:.:........|:|.||:.....|::.||.::||:.:||
  Fly   201 GVPYSCCINATDISSGLVNIMCGYGVQVRSVAAASKRIWTSGCIEIVRVWVERNLYVIAGVALGI 265

Human   244 ALLQIFGICLAQNLVSDIEAVRASW 268
            ||||:|.|.||:.|...|:..::.|
  Fly   266 ALLQLFVIYLAKTLEGQIDLQKSRW 290

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TSPAN5	NP_005714.2	Tetraspannin	15..257	CDD:395265	103/250 (41%)
		TM4SF9_like_LEL	113..233	CDD:239412	51/124 (41%)
Tsp86D	NP_001262468.1	Tetraspannin	51..283	CDD:278750	95/234 (41%)
		penumbra_like_LEL	132..255	CDD:239411	51/124 (41%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3882
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG48585
OrthoDB	1	1.010	-	-		D574036at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR19282
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X349
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	7	6.890