Protein Alignment TSPAN5 and Tsp3A

DIOPT Version :9

• Sequence 1: NP_005714.2
• Gene: TSPAN5 / 10098
• HGNCID: 17753
• Length: 268
• Species: Homo sapiens
• Sequence 2: NP_001245504.1
• Gene: Tsp3A / 31244
• FlyBaseID: FBgn0040334
• Length: 304
• Species: Drosophila melanogaster
• Alignment Length: 288
• Identity: 115/288 - (39%)
• Similarity: 165/288 - (57%)
• Gaps: 26/288 - (9%)

Human     3 GKHYKGPE------------VSCCIKYFIFGFNVIFWFLGITFLGIGLWAWNEKGVLSNISSITD 55
            |:.|.|.|            ||.|:||.||..|.:||..|...||||::|:.:|...:|.|  ..
  Fly    19 GRGYSGIEVHEVMHPHHFTYVSQCVKYMIFLLNFVFWLFGGLLLGIGVYAFRDKWEDANGS--VR 81

Human    56 LGGFDPVWL-----FLVVGGVMFILGFAGCIGALRENTFLLKFFSVFLGIIFFLELTAGVLAFVF 115
            |..|..|:|     .::.|.|:|::.|:||:||||||||||||:|:.|.:.|.||:...::.||.
  Fly    82 LENFYDVFLNISLVMILAGTVIFLVSFSGCVGALRENTFLLKFYSMCLLLFFLLEMAIAIVCFVC 146

Human   116 KDWIKDQL-YFFINNNIRAYRDDIDLQNLIDFTQEYWQCCGA--FGADDWNLNIYFNCTDSNASR 177
            ..::...| ..|.:..|.:||||.||||.|||.|:.::|||.  .|..||:.|.||||  |:.|.
  Fly   147 PQYMNTFLEKQFTHKIIHSYRDDPDLQNFIDFAQQEFKCCGLSNSGYQDWSKNEYFNC--SSPSV 209

Human   178 ERCGVPFSCC--TKDPAEDVINTQCGYDARQKPEVDQQIVIYTKGCVPQFEKWLQDNLTIVAGIF 240
            |:||||:|||  ..|.:..::|..|||..:..|..:...:|:|.||:.....|.:.||.::||..
  Fly   210 EKCGVPYSCCINATDISSGLVNIMCGYGVQNAPVPEATKLIWTSGCIEIVRVWAEHNLYVIAGNA 274

Human   241 IGIALLQIFGICLAQNLVSDIEAVRASW 268
            :||||:|:..|.||:.|...||..::.|
  Fly   275 LGIALIQLLVIYLAKTLEGQIELQKSRW 302

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TSPAN5	NP_005714.2	Tetraspannin	15..257	CDD:395265	104/251 (41%)
		TM4SF9_like_LEL	113..233	CDD:239412	49/124 (40%)
Tsp3A	NP_001245504.1	Tetraspannin	42..295	CDD:278750	106/256 (41%)
		penumbra_like_LEL	144..267	CDD:239411	49/124 (40%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3882
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG48585
OrthoDB	1	1.010	-	-		D574036at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR19282
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X349
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	7	6.890