Protein Alignment ACTR3 and Arp2

DIOPT Version :10

• Sequence 1: NP_005712.1
• Gene: ACTR3 / 10096
• HGNCID: 170
• Length: 418
• Species: Homo sapiens
• Sequence 2: NP_001259621.1
• Gene: Arp2 / 32623
• FlyBaseID: FBgn0011742
• Length: 399
• Species: Drosophila melanogaster
• Alignment Length: 405
• Identity: 138/405 - (34%)
• Similarity: 207/405 - (51%)
• Gaps: 36/405 - (8%)

Human     9 VVDCGTGYTKLGYAGNTEPQFIIPSCIA---IKESAKVGDQAQRRVMKGVDDLDFFIGDEAIE-K 69
            |.|.|||:.|.||||:..|..|.||.:.   |:...|:||...:.:  .||||  .:||||.: :
  Fly    10 VCDNGTGFVKCGYAGSNFPTHIFPSMVGRPMIRAVNKIGDIEVKDL--HVDDL--MVGDEASQLR 70

Human    70 PTYATKWPIRHGIVEDWDLMERFMEQVIF-KYLRAEPEDHYFLLTEPPLNTPENREYTAEIMFES 133
            ......:|:.:|:|.:||.|....:.... |.:..:|.:...||||||:|..:|||...|:|||.
  Fly    71 SLLEVSYPMENGVVRNWDDMCHVWDYTFGPKKMDIDPTNTKILLTEPPMNPTKNREKMIEVMFEK 135

Human   134 FNVPGLYIAVQAVLALAASWTSRQVGERTLTGTVIDSGDGVTHVIPVAEGYVIGSCIKHIPIAGR 198
            :.....|||:||||.|.|        :..::|.||||||||||:.||.|.:.:....:.:.||||
  Fly   136 YGFDSAYIAIQAVLTLYA--------QGLISGVVIDSGDGVTHICPVYEEFALPHLTRRLDIAGR 192

Human   199 DITYFIQQLLRDREVGIPPEQSLETAKAVKERYSYVCPDLVKEFNKYDTDGSKWIKQYTGINAIS 263
            |||.::.:||..|..........||.:.:||:..|:..|:..| .:...:.:..::.||     .
  Fly   193 DITRYLIKLLLLRGYAFNHSADFETVRIMKEKLCYIGYDIEME-QRLALETTVLVESYT-----L 251

Human   264 KKEFSIDVGYERFLGPEIFFHPEFANPDFTQPISEVVDEVIQNCPIDVRRPLYKNIVLSGGSTMF 328
            .....|.||.|||..||..|.|...|.: ...|:|:....||...||:|..|||:|||||||||:
  Fly   252 PDGRVIKVGGERFEAPEALFQPHLINVE-GPGIAELAFNTIQAADIDIRPELYKHIVLSGGSTMY 315

Human   329 RDFGRRLQRDLKRTVDARLKLSEELSGGRLKPKPIDVQVITHHMQRYAVWFGGSMLASTPE---- 389
            .....||:|::|     :|.|...|.....|.....:::.....::..|:.||::||...:
  Fly   316 PGLPSRLEREIK-----QLYLERVLKNDTEKLAKFKIRIEDPPRRKDMVFIGGAVLAEVTKDRDG 375

Human   390 FYQVCHTKKDYEEIG 404
            |:.   :|::|:|.|
  Fly   376 FWM---SKQEYQEQG 387

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ACTR3	NP_005712.1	ASKHA_NBD_Arp3-like	7..410	CDD:466822	138/405 (34%)
Arp2	NP_001259621.1	ASKHA_NBD_Arp2	7..393	CDD:466821	138/405 (34%)