Protein Alignment PQBP1 and pqbp1

DIOPT Version :10

• Sequence 1: NP_005701.1
• Gene: PQBP1 / 10084
• HGNCID: 9330
• Length: 265
• Species: Homo sapiens
• Sequence 2: NP_001002435.1
• Gene: pqbp1 / 796523
• ZFINID: ZDB-GENE-030616-158
• Length: 261
• Species: Danio rerio
• Alignment Length: 274
• Identity: 167/274 - (60%)
• Similarity: 203/274 - (74%)
• Gaps: 28/274 - (10%)

Human     1 MPLPVALQTRLAKRGILKHLEPEPEEEIIAEDYDDDPVDYEATRLEGLPPSWYKVFDPSCGLPYY 65
            ||||.||..|||||||:|..:.|.|||||||||||:.|||||||:|.||.:||||||.:||||||
Zfish     1 MPLPPALLARLAKRGIVKQSDHEAEEEIIAEDYDDNNVDYEATRIESLPSNWYKVFDSACGLPYY 65

Human    66 WNADTDLVSWLSPHDPNSVVTKSAKKLRSSNADAEEKLDRSHDKSDRGHDKSDRSHEKLDRGHDK 130
            ||.:|||||||||:||.:|:||:|||                .|.:.||:|.|..:||.:|..|:
Zfish    66 WNVETDLVSWLSPNDPAAVITKAAKK----------------PKGETGHEKGDGHYEKTERDRDR 114

Human   131 SDRGHDKS-DRDRERGYDKVDRERERDRERDRDRGYDK-ADREEGKERRHHRREELAPYPKSKKA 193
             ||..|:. :|||||..|: ||:..|||:|||||..|: .||:..::|| .|||:.|||.|||:.
Zfish   115 -DRERDRDRERDRERDRDR-DRDDGRDRDRDRDRDRDRERDRDRDRDRR-MRREDSAPYSKSKRG 176

Human   194 VS-------RKDEELDPMDPSSYSDAPRGTWSTGLPKRNEAKTGADTTAAGPLFQQRPYPSPGAV 251
            .|       ::.||:||||||:|||||||:|||||||||||||||||||||||||||||||||||
Zfish   177 GSGGGGSRKQQQEEMDPMDPSAYSDAPRGSWSTGLPKRNEAKTGADTTAAGPLFQQRPYPSPGAV 241

Human   252 LRANAEASRTKQQD 265
            ||||||.:|..:::
Zfish   242 LRANAENTRRLEEE 255

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PQBP1	NP_005701.1	WW	47..78	CDD:197736	23/30 (77%)
		Disordered. /evidence=ECO:0000269|PubMed:19303059	94..265		100/179 (56%)
		5 X 7 AA approximate tandem repeats of D-R-[SG]-H-D-K-S	104..138		12/33 (36%)
		3 X 2 AA tandem repeats of [DE]-R	139..144		3/4 (75%)
		7 X 2 AA tandem repeats of [DE]-R	150..163		8/12 (67%)
		Important for interaction with TXNL4A	245..255		9/9 (100%)
pqbp1	NP_001002435.1	None