DRSC/TRiP Functional Genomics Resources

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Protein Alignment PQBP1 and Pqbp1

DIOPT Version :10

Sequence 1:NP_005701.1 Gene:PQBP1 / 10084 HGNCID:9330 Length:265 Species:Homo sapiens
Sequence 2:NP_062351.2 Gene:Pqbp1 / 54633 MGIID:1859638 Length:263 Species:Mus musculus


Alignment Length:265 Identity:232/265 - (87%)
Similarity:251/265 - (94%) Gaps:2/265 - (0%)


- Green bases have known domain annotations that are detailed below.


Human     1 MPLPVALQTRLAKRGILKHLEPEPEEEIIAEDYDDDPVDYEATRLEGLPPSWYKVFDPSCGLPYY 65
            ||||||||||||||||||||||||||||||||||||||||||||:||||||||||||||||||||
Mouse     1 MPLPVALQTRLAKRGILKHLEPEPEEEIIAEDYDDDPVDYEATRIEGLPPSWYKVFDPSCGLPYY 65

Human    66 WNADTDLVSWLSPHDPNSVVTKSAKKLRSSNADAEEKLDRSHDKSDRGHDKSDRSHEKLDRGHDK 130
            ||.:|||||||||||||.||||||||:|::|||||:|.||:.:|.||.|:||||||||.||.|:|
Mouse    66 WNVETDLVSWLSPHDPNFVVTKSAKKVRNNNADAEDKSDRNLEKVDRNHEKSDRSHEKPDRSHEK 130

Human   131 SDRGHDKSDRDRERGYDKVDRERERDRERDRDRGYDKADREEGKERRHHRREELAPYPKSKKAVS 195
            :||.|:|:||:|||.||||||||:||||  |:|.:|||||||||:||||||||||||||:|||.|
Mouse   131 ADRNHEKNDRERERNYDKVDRERDRDRE--RERAFDKADREEGKDRRHHRREELAPYPKNKKATS 193

Human   196 RKDEELDPMDPSSYSDAPRGTWSTGLPKRNEAKTGADTTAAGPLFQQRPYPSPGAVLRANAEASR 260
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Mouse   194 RKDEELDPMDPSSYSDAPRGTWSTGLPKRNEAKTGADTTAAGPLFQQRPYPSPGAVLRANAEASR 258

Human   261 TKQQD 265
            |||||
Mouse   259 TKQQD 263

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
PQBP1NP_005701.1 WW 47..78 CDD:197736 28/30 (93%)
Disordered. /evidence=ECO:0000269|PubMed:19303059 94..265 142/170 (84%)
5 X 7 AA approximate tandem repeats of D-R-[SG]-H-D-K-S 104..138 21/33 (64%)
3 X 2 AA tandem repeats of [DE]-R 139..144 3/4 (75%)
7 X 2 AA tandem repeats of [DE]-R 150..163 9/12 (75%)
Important for interaction with TXNL4A 245..255 9/9 (100%)
Pqbp1NP_062351.2 WW 47..78 CDD:197736 28/30 (93%)
Disordered. /evidence=ECO:0000250|UniProtKB:O60828 94..263 142/170 (84%)
5 X 7 AA approximate tandem repeats of D-R-[NS]-H-E-K-S 104..138 21/33 (64%)
3 X 2 AA tandem repeats of [DE]-R 139..144 3/4 (75%)
6 X 2 AA tandem repeats of [DE]-R 150..161 9/12 (75%)
Important for interaction with TXNL4A. /evidence=ECO:0000250|UniProtKB:O60828 243..253 9/9 (100%)

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