DRSC/TRiP Functional Genomics Resources

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Protein Alignment PQBP1 and Pqbp1

DIOPT Version :10

Sequence 1:NP_005701.1 Gene:PQBP1 / 10084 HGNCID:9330 Length:265 Species:Homo sapiens
Sequence 2:NP_001013979.2 Gene:Pqbp1 / 302557 RGDID:1549750 Length:263 Species:Rattus norvegicus


Alignment Length:265 Identity:230/265 - (86%)
Similarity:251/265 - (94%) Gaps:2/265 - (0%)


- Green bases have known domain annotations that are detailed below.


Human     1 MPLPVALQTRLAKRGILKHLEPEPEEEIIAEDYDDDPVDYEATRLEGLPPSWYKVFDPSCGLPYY 65
            ||||||||||||||||||||||||||||||||||||||||||||:||||||||||||||||||||
  Rat     1 MPLPVALQTRLAKRGILKHLEPEPEEEIIAEDYDDDPVDYEATRIEGLPPSWYKVFDPSCGLPYY 65

Human    66 WNADTDLVSWLSPHDPNSVVTKSAKKLRSSNADAEEKLDRSHDKSDRGHDKSDRSHEKLDRGHDK 130
            ||.:|||||||||||||.||:|||||||:||||||:|.:|:.:|.||.|:||||||||.||.|:|
  Rat    66 WNVETDLVSWLSPHDPNFVVSKSAKKLRNSNADAEDKSERNLEKVDRNHEKSDRSHEKPDRSHEK 130

Human   131 SDRGHDKSDRDRERGYDKVDRERERDRERDRDRGYDKADREEGKERRHHRREELAPYPKSKKAVS 195
            :||.|:||||:|||.||||||||:||||  |:|.:||||||:||:|||||||:||||||:|||.|
  Rat   131 ADRNHEKSDRERERNYDKVDRERDRDRE--RERAFDKADREDGKDRRHHRREDLAPYPKNKKATS 193

Human   196 RKDEELDPMDPSSYSDAPRGTWSTGLPKRNEAKTGADTTAAGPLFQQRPYPSPGAVLRANAEASR 260
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Rat   194 RKDEELDPMDPSSYSDAPRGTWSTGLPKRNEAKTGADTTAAGPLFQQRPYPSPGAVLRANAEASR 258

Human   261 TKQQD 265
            :||||
  Rat   259 SKQQD 263

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
PQBP1NP_005701.1 WW 47..78 CDD:197736 28/30 (93%)
Disordered. /evidence=ECO:0000269|PubMed:19303059 94..265 140/170 (82%)
5 X 7 AA approximate tandem repeats of D-R-[SG]-H-D-K-S 104..138 20/33 (61%)
3 X 2 AA tandem repeats of [DE]-R 139..144 3/4 (75%)
7 X 2 AA tandem repeats of [DE]-R 150..163 9/12 (75%)
Important for interaction with TXNL4A 245..255 9/9 (100%)
Pqbp1NP_001013979.2 WW 47..78 CDD:197736 28/30 (93%)
Disordered. /evidence=ECO:0000250|UniProtKB:O60828 94..263 140/170 (82%)
5 X 7 AA approximate tandem repeats of D-R-[NS]-H-E-K-S 104..138 20/33 (61%)
3 X 2 AA tandem repeats of [DE]-R 139..144 3/4 (75%)
6 X 2 AA tandem repeats of [DE]-R 150..161 9/12 (75%)
Important for interaction with TXNL4A. /evidence=ECO:0000250|UniProtKB:O60828 243..253 9/9 (100%)

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