Protein Alignment PQBP1 and pqbp1

DIOPT Version :10

• Sequence 1: NP_005701.1
• Gene: PQBP1 / 10084
• HGNCID: 9330
• Length: 265
• Species: Homo sapiens
• Sequence 2: NP_001135500.1
• Gene: pqbp1 / 100216040
• XenbaseID: XB-GENE-6455289
• Length: 198
• Species: Xenopus tropicalis
• Alignment Length: 262
• Identity: 156/262 - (59%)
• Similarity: 172/262 - (65%)
• Gaps: 70/262 - (26%)

Human     1 MPLPVALQTRLAKRGILKHLEPEPEEEIIAEDYDDDPVDYEATRLEGLPPSWYKVFDPSCGLPYY 65
            ||||:|||.||||||||:|::.||.|||||||||||.|||||||:|.|||||||||||.||||||
 Frog     1 MPLPLALQARLAKRGILRHVDSEPAEEIIAEDYDDDHVDYEATRVESLPPSWYKVFDPICGLPYY 65

Human    66 WNADTDLVSWLSPHDPNSVVTKSAKKLRSSNADAEEKLDRSHDKSDRGHDKSDRSHEKLDRGHDK 130
            ||.:||||:||||:||.:|:|::|.|
 Frog    66 WNVETDLVAWLSPNDPGAVITRAAAK--------------------------------------- 91

Human   131 SDRGHDKSDRDRERGYDKVDRERERDRERDRDRGYDKADREE--GKERRHHRREELAPYPKSKKA 193
                            .||....|:..|           |||  .||||..||||:||||||||
 Frog    92 ----------------QKVTEPEEKPLE-----------REEVIMKERRFSRREEVAPYPKSKK- 128

Human   194 VSRKDEELDPMDPSSYSDAPRGTWSTGLPKRNEAKTGADTTAAGPLFQQRPYPSPGAVLRANAEA 258
             .||:|||||||||:||||||||||||||||||||||||||||||||||||||||||||||||||
 Frog   129 -GRKEEELDPMDPSAYSDAPRGTWSTGLPKRNEAKTGADTTAAGPLFQQRPYPSPGAVLRANAEA 192

Human   259 SR 260
            ||
 Frog   193 SR 194

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PQBP1	NP_005701.1	WW	47..78	CDD:197736	25/30 (83%)
		Disordered. /evidence=ECO:0000269|PubMed:19303059	94..265		86/169 (51%)
		5 X 7 AA approximate tandem repeats of D-R-[SG]-H-D-K-S	104..138		0/33 (0%)
		3 X 2 AA tandem repeats of [DE]-R	139..144		0/4 (0%)
		7 X 2 AA tandem repeats of [DE]-R	150..163		2/12 (17%)
		Important for interaction with TXNL4A	245..255		9/9 (100%)
pqbp1	NP_001135500.1	None