|
Human 49 SKSKPADCRALIDKLKVCNDEQLLLE-LQQIKTWNIGKCELYHWVDLLDRFDGILADAGQTVENM 112
|....|:||.|||:|........||| |..:..|..||||||||:::|||||.||.:|.:.|...
Fly 12 SSELTAECRELIDELTKRRTRAELLEFLDTVHVWIYGKCELYHWIEILDRFDKILEEASRHVNGN 76
Human 113 SWMLVCDRPEREQLKMLLLAVLNFTALLIEYSFSRHLYSSIEHLTTLLASSDMQVVLAVLNLLYV 177
.::|.||...:|....|||.|||||.||||:|||||||:||||||.||:|.:|.:|||||||||:
Fly 77 EFVLQCDTNFQETDVTLLLHVLNFTTLLIEHSFSRHLYNSIEHLTVLLSSQNMDIVLAVLNLLYM 141
Human 178 FSKRSNYITRLGSDKRTPLLTRLQHLAESWGGKENGFGLAECCRDLHMMKYPPSATTLHFEFYAD 242
||||||:|.||..:|:..|:.:|.::||.||....|..|.:||.....::: ...|..::..:
Fly 142 FSKRSNFIPRLPFEKKELLIVKLFNIAERWGDPNYGLSLKDCCIGEPKLEF---LYQLCIDYVDE 203
Human 243 PGAEVKIEKRTTSNTLHYIHIEQLDKISESPSEIMESLTKMYSIPKDKQMLLFTH-IRLAHGFSN 306
.|...::|.....:..| :.|..|:::::....|.|.:...:...| :||..||:|
Fly 204 HGHAAQLEIPDMMDLCH----------TASAPEVIKTIAGQISKPSEAIKMRIAHRVRLISGFNN 258
Human 307 HRKRLQAVQARLHAISILVFVSPFAVYSNALQESANSILYNGLIEELVDVLQITDKQLMEIKAAS 371
::.|||.|||||.|:||| :||||||::.:.:||.|..|||.:::...|..|:||:||.
Fly 259 YKLRLQFVQARLQAVSIL-------IYSNALQDNTDKVLYAGFGEELCELIDKEDVHLVEIRAAV 316
Human 372 LRTLTSIVHLERTP-------KLSSIIDCTGTASYHGFLPVLVRNCIQAMIDPSM-DPYPHQFAT 428
||||||::|.:|.| :|..|:..||.....|.||:|||:||..:....: :.||...||
Fly 317 LRTLTSMLHFDRNPNVPRAGSRLMKIVHYTGAERQGGTLPLLVRDCIDNLTTHGLTERYPLILAT 381
Human 429 ALFSFLYHLASYDAGGEALVSCGMMEALLKVIKFLGDEQDQITFVTRAVRVVDLITNLDMAAFQS 493
:|||.|||||||:.||.|||..|||::||.||.:.|.:.:.||||||||||:|||||:|:|.|..
Fly 382 SLFSLLYHLASYEMGGTALVKSGMMQSLLCVISWPGVDLEHITFVTRAVRVIDLITNIDIARFHQ 446
Human 494 HSGLSIFIYRLEHEVDLCRK---ECPFVIKPKIQRPNTTQEGEEMETDMDVADVAMESSPGSSIS 555
::||::||.|||.|:..|.| :....:| .:|.::..:::|.:|..|..:|...|.:.|
Fly 447 NNGLNVFIDRLEKEIKSCCKALADIGITLK-----ESTLRDDHKLDTSLDHVDEDVEDGSGENAS 506
Human 556 MEHRLDVELRASGSSS--STNISSGPSPGPS----------PGPGTGPG----PGPGPGPGPGPG 604
: .||::| ..|.|.|.:...| .|.|:|.| .|.......|..
Fly 507 V---------TSGNASPRRDNSSDGATGAGSIVYRAYHEHIGGAGSGAGLLDIGGARSSLSGGSS 562
Human 605 PGPGPGPGPGPGPGPGPRPGV---------------------------------QCIPQRAALLK 636
...|.|.|.....|...||.. .|:.|||||||
Fly 563 GTSGMGAGSINRDGSAARPPAIMYPTNSYYARPLAERKAELSSQLPSSLAPKKPSCVTQRAALLK 627
Human 637 SMLNFLKKAIQDPAFSDGIRHVMDGSLPTSLKHIISNAEYYGPSLFLLATEVVTVFVFQEPSLLS 701
||||||||:|||.|....:|::|:.||..||:|||:||||||||||||||:||||:||.||||||
Fly 628 SMLNFLKKSIQDHAHFSNMRNIMETSLTQSLRHIIANAEYYGPSLFLLATDVVTVYVFNEPSLLS 692
Human 702 SLQDNGLTDVMLHALLIKDVPATREVLGSLPNVFSALCLNARGLQSFVQCQPFERLFKVLLSPDY 766
||||.|:|.|||.|||.|||||||||||||||||||||||.|||..|:...||:::.||||||||
Fly 693 SLQDLGITSVMLKALLQKDVPATREVLGSLPNVFSALCLNERGLFEFLSYDPFDKVLKVLLSPDY 757
Human 767 LPAMRRRRSSDPLGDTASNLGSAVDELMRHQPTLKTDATTAIIKLLEEICNLGRDPKYIC---QK 828
|.|||||||||||||||:|||:|:|:|::|.|.|:.|||.||::||.|:..||.||.:|| .|
Fly 758 LVAMRRRRSSDPLGDTATNLGNAMDDLIKHHPYLRADATEAIVRLLNELVRLGSDPSFICWRANK 822
Human 829 PSIQKADGT---------ATAPPPR------------SNHAAEEASSEDEEEEEVQAMQSFNSTQ 872
.|.....|: |:.|.|. ...||:...|..:::::...|.|.:..|
Fly 823 ESSGSGSGSGSHGGGHHVASTPSPMVMVAGTGSASSVLQGAADTNDSSGDDDDDDDEMSSASQQQ 887
Human 873 QNETEPNQ---------------------------------QVVGTEERIPIPLMDYILNVMKFV 904
|..|.|.| :||...||..|||:|||||||||:
Fly 888 QQPTTPGQGGGPSTPRTQQAGGVVGSGAGATGTPAAASQAVKVVTPPEREAIPLIDYILNVMKFI 952
Human 905 ESILSNNTTDDHCQEFVNQKGLLPLVTILGLPNLPIDFPTSAACQAVAGVCKSILTLSHEPKVLQ 969
|:|.||:...|||:|||...||.|::.:|.|||||:|.|.|...||||.|||:||:.:.|.|||.
Fly 953 EAIFSNSPNGDHCREFVLHGGLKPILQLLSLPNLPVDSPVSTTSQAVANVCKAILSQAQETKVLD 1017
Human 970 EGLLQLDSILSSLEPLHRPIESPGGSVLLRELACAGNVADATLSAQATPLLHALTAAHAYIMMFV 1034
..|.||..|::.|:||.:....|||||||.||.|...:.|...:|:.||:||.::..|.|::|.|
Fly 1018 VALKQLADIVAQLKPLIKHFTFPGGSVLLAELVCCQRLEDGFANAEYTPILHNMSFVHGYVVMLV 1082
Human 1035 HTCRVGQSEIRSISVNQWG--SQLGLSVLSKLSQLYCSLVWESTVLLSLCT--PNSLPSGCEFGQ 1095
|.||...:::|:|.:.:|| .:.|:.:|.:|.|||.|||||||:||:||: |...|.
Fly 1083 HLCRNASNDMRTILLKRWGVNRETGVQLLQQLVQLYISLVWESTILLNLCSDEPTQHPD------ 1141
Human 1096 ADMQKLVPKDEKAGTTQGGKRSDGEQDGAAGSMDASTQGLLEGIGLDGDTLAPMETDEPTASDSK 1160
:..||.| .:...|||:.|..|:. |........::
Fly 1142 ------LIWDEIA----------AQMSAAAGTADPLTEA---------------ELSRKLERAAE 1175
Human 1161 GKSKITPAMAARIKQIKPLLSASSRLGRALAELFGLLVKLCVGSP-VRQRRSHHAAST-TTAPTP 1223
.::|.|| ..:.:.||.||:||||||||||||.|.||||.|||| .||||.:...|. |..|||
Fly 1176 FRTKYTP--EEQFRYIKSLLAASSRLGRALAELLGTLVKLSVGSPQTRQRRINDLISNITKVPTP 1238
Human 1224 AARSTASALTKLLTKGLSWQPPPYTPTPRFRLTFFICSVGFTSPMLFDERKYPYHLMLQKFLCSG 1288
.||..|..|:.:|..|.|.:.....|.|:.:|||.|||||||.|||||:::..:|||:.:|....
Fly 1239 EAREIARILSSILVNGFSHESILPKPVPKLKLTFLICSVGFTGPMLFDDKRSAFHLMISQFCAEN 1303
Human 1289 GHNALFETFNWALSMGGKVPVSEGLEHS-----------------DLPDGTGEFLDAWLMLVEKM 1336
|..|.||.|.||||:.. ||:..|.. |.|:||||||||||.|:|||
Fly 1304 GLKAFFEMFYWALSLDN---VSQKFEFDQWASMEDLMQSHEDDKRDCPEGTGEFLDAWLQLLEKM 1365
Human 1337 VNPTTVLESPHSLPAKL---PGGVQNFPQFSALRFLVVTQKAAFTCIKNLWNRKPLKVYGGRMAE 1398
|||..:|:||:::..:| |..|...|.| :|:...:.|...::.:|.|:|:..||..|.|
Fly 1366 VNPRAMLDSPYTMSPRLNYMPDSVPFEPVF----YLIHIHQLAMQALRRIWARRPIPNYGPSMFE 1426
Human 1399 SMLAILCHILRGEPVIRERLSKEKEGSRGEE------DTGQEEGGSRREPQVNQQQLQQLMDMGF 1457
:|:.||.|:::....:.:|.....:..:.|. |.| :|...::.|.||||
Fly 1427 TMILILKHLIKSHQTLLDRYHTRMKEIKFENLYIRSTDDG-----------LNADHIKTLTDMGF 1480
Human 1458 TREHAMEALLNTSTMEQATEYLLTHPP----PIMGGVVRDLSMSEEDQMMRAIAMSLGQDIPMDQ 1518
...|.:|||...:::|:||:|||.:|. ...|| ....|.........|..|.:..|:|.|
Fly 1481 MHYHVIEALRTNASLEEATDYLLNNPEASSLSTTGG-QSSSSAPPPPPPPSASTMDIDVDVPAD- 1543
Human 1519 RAESPEEVACRKEEEERKAREKQEEEEAKCLEKFQDADPLEQDELHTFTDTMLPGCFHLLDELPD 1583
.||.: .:.........:.:..|.:... ....|.|..:...|..::.:||
Fly 1544 -GESTQ------SKSSTSPNSSYDYKHLKLMPSL---------IFDRFCDEAISRAFEFMEAIPD 1592
Human 1584 TVYRVCDLIMTAIKRNGADYRDMILKQVVNQVWEAADVLIKAALPLTTSDTKT--VSEWISQMAT 1646
||....|||....:|:....:.:.:...|..:.:..|..::...|..|:.:|. :.|.::.|.
Fly 1593 TVNSAADLIAVLYRRHNHLNKQVFVTNFVRNIIQWVDFTLQLFEPAKTTGSKASRLEECLTGMT- 1656
Human 1647 LPQASNLATRILLLTLLFEE----LKLPCAWVVESSGILNVLIKLLEVV-QPCLQAAKE----QK 1702
|:.|..|:...|||.|| |..|....:.:...:..|:|||:.: |..|:.:.| |:
Fly 1657 ---ATRLFVRLKTSTLLLEENYSDLHRPLVEAITAQDAMVSLVKLLDCMSQWMLEQSTETNTGQQ 1718
Human 1703 EVQTPKWITPVLLLIDFYEKTAISSKRRAQMTKYLQSNSNNWRWFDDRSGRWCSYSASNNSTIDS 1767
....|:|:..::.|||..:..:...:|:|.|... :|:.|||:|..:|:|.:||.:||..|.:
Fly 1719 RATVPRWVQNLVDLIDAIDSISHILQRKANMRAV---SSDVWRWYDASTGKWNAYSEANNELIRN 1780
Human 1768 AWKSGETSVRFTAGRRRYTVQFTTMVQVNEETGNRRPV--------MLTLLRVP----------- 1813
|:.:||..:....||:|.||....|.||:|.:|..||| .:|.|..|
Fly 1781 AYAAGERWLYINIGRQRCTVSLNCMTQVSEASGTHRPVCPALKLSEAITSLNNPVALHKVEHILN 1845
Human 1814 RLNKNSKNSNGQ-------ELEKTLEESKEMDIKRKENKGN--------DTPLALES-----TNT 1858
|:.:.:.:.:|. .|.:.:..:.....::.||..| |.|.|..| |.|
Fly 1846 RVVRTAPDGSGTVHSDELISLRQLVNFTDGQQPQQSENSANPSEEATSEDGPAAANSGSPPATMT 1910
Human 1859 EKETSLEETKIGEILIQG------------------LTEDMVTVLIRACVSMLGVPVD------- 1898
.:..:.:::.......:. |.|:.|.:....|..::|..||
Fly 1911 TRSKTRQKSAAAAAAAKNKSQSGGSPPIPKRTQKIILNEEQVGLSKFDCGRIIGSIVDLLQPSHQ 1975
Human 1899 --PDTLHATLRLCLRLTRDHKYAMMFAELKSTRMILNLTQSSGFNGFTPLVTLLLRHIIEDPCTL 1961
.:|..:.||||.||||::..|.:|......||:|:|.|:..|.||.....::|||::|.|..|
Fly 1976 MLNETKLSLLRLCARLTRNYDNAQVFIRRGGVRMLLHLQQACSFMGFPTYANIILRHVLEAPPVL 2040
Human 1962 RHTMEKVVRSAATSGAGSTTSGVVSGSLGSREINYILRVLGPAACRNPDIFTEVANCCIRIALPA 2026
:..||:|: |...:|:| .:|.|::.|:|..:..|..|||.||...|...::.....
Fly 2041 QEAMERVL--------GMRAAGIV--PVGHRDLIYVLTQVSSAVSRNPQIFVAAAKEMLKGEYLI 2095
Human 2027 PRGSGTASDDEFENLRIK---GPNAVQLVKTTP--LKPSPLPVIPDTIKE---------VIYDML 2077
...|.|.:||....::.| .|.|. ....|| ..|:|.|...|.:|: |:.::|
Fly 2096 NTNSTTLADDARVMVKSKFGQQPTAA-AGGATPHNQTPTPPPAAKDELKDDPQVQSSVAVLKELL 2159
Human 2078 NALAA----YHAPEEADKSDPKPGVMTQEVGQLLQDMGDDVYQQYRSLTRQSSDFDTQSGFSINS 2138
:.|.. |......|:. |...:|||
Fly 2160 HGLVQPCWHYGGTGSLDRG--------QGAAELLQ------------------------------ 2186
Human 2139 QVFAADGASTETSASGTSQG-----------EASTPEESRDGKKDKEGDRASEEGKQKGKG---- 2188
.....||:|| |...|..|: |:...|..|:..| |.|:.
Fly 2187 ----------PDQPPGTAQGCHDDELYFRFQETPAPVSSK--KQSSSGGGAAAAG-QTGQATEKF 2238
Human 2189 ----------------SKPLMPTSTILRLLAELVRSYVG-IATLIANYSYTVGQSELIK-EDCSV 2235
:||.:..:|:|:|||:..|:|.. :..::.::.||...|.||. ...:.
Fly 2239 EPCCCTWHIPTSGHTHAKPTISRATLLKLLADSTRAYQSLVPRVLLSHVYTPADSPLISAPQQTF 2303
Human 2236 LAFVLDHLLPHTQNAEDKDTPALARLFLASLAAAGSGTDAQVALVNEVKAALGRALAMAESTEKH 2300
|..:||..||.||.....:...:.|:.:.||:........||.:..|:.||:.||||..:|.|||
Fly 2304 LGVLLDRFLPITQRHHVPEVSTMTRVLICSLSDCYQQPGVQVHVAEELHAAVARALAQPDSAEKH 2368
Human 2301 ARLQAVMCIISTIMESCPSTSSFYSSATAKTQHNGMNNIIRLFLKKGLVNDLARVPHSLDLSSPN 2365
.|||.:|.:...::|| ...|... |...||:.|:.|::|::..|.:|....|||:.|
Fly 2369 TRLQVLMSLFPNLIES----PMLYDKV-----HMHRNNMYRVLLRQGVMTYLTKVAQYKDLSNHN 2424
Human 2366 MANTVNAALKPLETLSRI------VNQPSSLFGSKSASSKNKS---------------------- 2402
..:|:.|.|:|:|.|.|. :.....||||......|.|
Fly 2425 TLSTLAAILRPMEILLRFSVSTTTLGSKRILFGSGGPGGPNASGNGNNTAGGSSGNGPGSGNTYG 2489
Human 2403 ----------------------EQDAQGA------------------------SQDSSSNQQDPG 2421
..:|.|. |.|.:.:.:|..
Fly 2490 TIINRRLYPRLAARTGFGSAMERSNAMGGEHVLRDIIRNVLSDRRHAFEFIFNSDDMAVDSEDAA 2554
Human 2422 EPG-----------------EAEVQEEDH----DVTQTEVADGDIMDGEAETDSVVI-AGQPEVL 2464
.|| ...|..... ||.:.....||..|..|...|... |||....
Fly 2555 APGSGVGGGGSGAGSVGGGVSGSVSGNSSAAVIDVVEERSNGGDTNDPPANVSSASSGAGQSSTS 2619
Human 2465 SSQEMQVENELEDLIDELLERDG-----------GSGNSTIIVSRSGEDE--------------- 2503
......|.| .:.|.|:.|:.:| |||:.::..|.||:..
Fly 2620 GGPVRPVVN-FDQLWDDFLQSEGLRLASRSGGGAGSGSGSVGASSSGQQNGSNTTASSTNSGNNS 2683
Human 2504 --------------------------SQEDVLMDE------------------APS-----NLSQ 2519
|...|:.|. ||. |.|.
Fly 2684 GIGNLRLRTNPDVDVGSGNGSGSGSGSNAGVVNDNGISGGGGSDGASTSSDTGAPGGARDLNASL 2748
Human 2520 ASTLQANREDSMNILDPEDEEEHTQEEDSSGSNEDEDDSQDEEEEEEEDEE-------------- 2570
...:..:..|| ||..|.:...|||....::..|:..||..|.:.|||
Fly 2749 LGDVSTSESDS----DPSTENDERNEEDEDEDDDAPDEDVDEHSETDVDEERSRQFIEVFDHIYE 2809
Human 2571 --------------DDQEDDEGEEGDEDDDDDGSEMELDEDYPD--------------------- 2600
:|.:|||.:..|:||||:.::.::.|:...
Fly 2810 PESSETASNDADVDNDDDDDEDDVDDDDDDDEDNDDDVREEVQSVMDAEIENRIDIALALVSSNN 2874
Human 2601 -------MNASPLVRFERFDREDDLIIEFDNMFSSA---TDIPPSPG----------------NI 2639
:|||......|.:.:|::..|.|::.:.. .|:.|..| .:
Fly 2875 RPRRSAAVNASGDGSANRTNPDDEVDDEDDDVDADPDGDPDVDPISGPSAAQAEAYLYERLGSGL 2939
Human 2640 PTTHPLMVRHADHSSL-----------TLGSG---------------SSTTRLTQGIGR-SQRTL 2677
..|.|:..|...:||: ..||| |||...|..||. :...|
Fly 2940 MPTPPVGFRVRMNSSIAQPLDIDVNGGNAGSGSNAGATGSSGGSGQRSSTGGTTASIGAIASAAL 3004
Human 2678 RQLTAN-------------------TGHTIHVHYPG---NRQPNPPLILQRLLG-PSAAADILQL 2719
|..:.: :|..|..:..| |....|.:.|:|..| |.:...:.:|
Fly 3005 RPSSGSWMAPDFNFIRISGGDSSMGSGPAIGGNANGGDMNVFITPSMSLERAGGAPGSGQTMSEL 3069
Human 2720 SSSLPLQSRG---------------------------------RARLLVGNDDVHIIARSDDELL 2751
.:..|..:.| |.||| .|
Fly 3070 LNEQPTGAGGGGGGGSASGVGGVGANGGTTGQHPNATLCTNGVRRRLL---------------YL 3119
Human 2752 DDFF------HDQSTATSQAGTLSSIPTALTRWTEECKVLDAESMHDCVSVVKVSIVNHLEFLRD 2810
|..: |...|..:|..|.:. .||..|.||..:||.||..|........::.|| .
Fly 3120 DQQYCVCMPTHQNPTEETQMETFTQ--DALHWWLEEATLLDMESQTDACLYAAHFLLPHL----I 3178
Human 2811 EELEERREKRRKQLAEEETKITDKGKEDKENRDQSAQCT-------------------------- 2849
:||:...::|:::.|..::.....| .|...::..|
Fly 3179 KELKAAHQQRKQEEAARQSTTPASG----SNASATSSSTTSVVGTAAPTATSSIASGLLANAVSA 3239
Human 2850 ------------ASKSNDSTEQN----LSDGTPMPDSYPTTPSST-DAATSESKETLG------- 2890
|:.:...|.:: |...|..|.|..:..|:| :.|||::..|.|
Fly 3240 GSGSSSLVVPPVAASATGGTRRSSIPVLISSTLGPSSASSATSATGNGATSDATTTTGGPTRNFS 3304
Human 2891 ---TLQSSQQQPTLPTPPALGEVPQELQSP-------------AGEGGSSTQLL----------- 2928
:..||:.|.|...|...|.:.|:.|.| ..||..||...
Fly 3305 SVDSNVSSETQTTTRPPRQRGGLRQQSQLPFNIYAEIDLTNEQDSEGDRSTSTTTGTAADGAESQ 3369
Human 2929 ----------------------MPVEPEELGPTRPSGEAETTQMEL------------------- 2952
:|:.|....|:||....:.|::.|
Fly 3370 SQHNSSSTAAQVAVPQHQRHPPVPLLPSSGRPSRPHTRLDETELLLLQLTDRQIRNRLQGSSGHT 3434
Human 2953 -----------------------------------------SPAPTITSLS-------------- 2962
:||||:.|:.
Fly 3435 NSSRTSGSALINARPNRDLPACLQRHDHPAGSIFPRPSANRTPAPTLVSMPTPMSNAALEQLNVT 3499
Human 2963 -------------PERAE-DSDALTAV------SSQLEGS-----------PMDTSSLASCTLEE 2996
|...| |.|.|..: .:|.|.. |.||:.|.....:.
Fly 3500 APDVVRTDRNFALPSSLEVDVDVLPGIVDLPQQEAQPEDDQLLLPPPPPPPPSDTTPLVHAEDDL 3564
Human 2997 AVGDTSAAGSSEQPRAGSSTPGDAPPAVAEVQGRSDGSGESAQP---PEDS-----SPPASSESS 3053
..|...:||:.|:..| ||||... ::...||.|| ||.| :|.|.|...
Fly 3565 WPGTVVSAGTREESSA---------PAVATES--TEAVNESNQPEPTPESSESTSPNPQAPSAEP 3618
Human 3054 STRDSAVAIS---GADSRGILEE------------PLPSTSSEEEDPLAGISLPEGVDPSFLAAL 3103
:..:...|:. ||.:....|| .:...|.|....|..:.:||||||||||||
Fly 3619 TPLEPGAAVDASVGAQTPATTEEAASTAGASGTTATITDMSPEVRAALGDLEVPEGVDPSFLAAL 3683
Human 3104 PDDIRREVLQNQLGIRPPTRTAPSTNSSAPAVVGNPGVTEVSPEFLAALPPAIQEEVLAQQRAEQ 3168
|.::|.||:|..|.:: |.......:| ..:.:..:.||:||||||||..||.|||.|||.||
Fly 3684 PSEMREEVIQEHLRMQ---RIRQRAQQNA-IQIAHDSLVEVNPEFLAALPLNIQSEVLMQQRIEQ 3744
Human 3169 QRRELAQNASSDTPMDPVTFIQTLPSDLRRSVLEDMEDSVLAVMPPDIAAEAQALRREQEARQRQ 3233
| |:.||.|:.:.|:|...|.|.||.:||:::|.|||:|.:|.:||::|||||.|||:.|:|.
Fly 3745 Q-RQAAQTANPEDPVDTAAFFQNLPENLRQAILTDMEESQIASLPPELAAEAQFLRRDWESRN-- 3806
Human 3234 LMHERLFGHSSTSALSAI------LRSPAFTSRL----SGN---RGVQYTRLAVQRGGTFQMGGS 3285
..|:..|..::|||.. |....:.|.: ||| :..|:|.:..|. .
Fly 3807 --GARMDAHPPSNALSRFQTTLQSLDDTRWHSSIWYDASGNAQPQHHQHTTIVHQH--------P 3861
Human 3286 SSHNRPS-GSNVDTLLRLRGRLLLDHEALSCLLVLLFVDEPKLNTSRLHRVLRNLCYHAQTRHWV 3349
.:|:.|: |..:..|:.....:|||.::|:.||:.|||::.|:|:.|||||:||||:|..||.|:
Fly 3862 HAHHAPNMGKPLALLMMEDENILLDPDSLATLLLFLFVEDQKVNSMRLHRVIRNLCHHEPTRDWI 3926
Human 3350 IRSLLSILQRSSESELCIETPKLTTSEEKGKKSSKSCGSSSHENRPLDLLHKMESKSSNQLSWLS 3414
|.:|:||:|:::| .:.:.|:.....:| .||.
Fly 3927 ISALISIIQKTNE-------------------DNANFGAGQAGGKP---------------EWLK 3957
Human 3415 VSMDAALGCRTNIFQIQRSGGRKHTEKHASGGSTVHIHPQAAPVVCRHVLDTLIQLAKVFPSHFT 3479
:.:|||.|.::|||.|.| .:.....::.|:||||.::.|:.||.|..|||.:||.|.
Fly 3958 LRVDAAFGYKSNIFLINR--------LYEGSARSISINPQAAQMIVRNCLDLLFVLAKHYPSSFV 4014
Human 3480 ----------------------------------------------------------------- 3479
Fly 4015 PFNRDVKARRILSAVFGMPSPTAGSGGGAGSGSAASGGLTGYDDVPPGGTLDFRSRFCRYQVVNR 4079
Human 3480 -----------------QQRTKETNCESDRERGNKACSPCSSQSSSS----GICTDFWDLLVKLD 3523
.:....:...:.:.......|...||:..| ....:|||:::.:|
Fly 4080 LRSIFDDHPAPKPSVPLDEAPSTSKAAAAKAAATAKVSTAGSQNKHSVPYQTNAKNFWDVVLNID 4144
Human 3524 NMNVSRKGKNSVKSVPVSAGGEGETSP-----YSLEASPLGQLMNMLSHPVIRRSSLLTEKLLRL 3583
.....|.. :|...|:::....|..| .|...||.|||:.||.:.||.||..||:.|::|
Fly 4145 QQTQVRLA--NVAQFPLTSQPAWEWQPNTADFLSFSESPFGQLLEMLPYKVICRSPHLTDMLVKL 4207
Human 3584 LSLISIALPENKVSEAQANSGSGASSTTTATSTTSTTTTTAASTTPTPPTAPTPVTSAPALVAAT 3648
|:.:|..||: |.:....|..................||:..|.||..|...|:....:...
Fly 4208 LASLSTELPK----EEELLPLSDQMPPLVPIGPVQRAGAAAAAAHPPPPQPPAENTATATEIGDG 4268
Human 3649 AISTIVVAASTTVTTPT----------TATTTVSISPTTKGSKSPAKVSDGGSSSTDFKMVSSGL 3703
..:.|...||.....|. |...|:|::.....||...|: .|.:|
Fly 4269 LAANIEEQASPASGNPASGDSNAGAKRTQLPTLSVALPVTPSKPRRKI-----YSKNF------- 4321
Human 3704 TENQLQLSVEVLTSHSC-SEEGLEDAANVLLQLSRGDSGTRDTVLKLLLNGARHLGYTLCKQIGT 3767
:||||.:|||| |.| :.|||::.|.:::.|::....:....::.|......|...:.:.|..
Fly 4322 --SQLQLVIEVLT-HQCGTTEGLDNVAKLIVNLTQCSQASSAIFIQYLTAAILGLAEEVRQAIQM 4383
Human 3768 LLAELREYNLEQ-----------------QRRAQCETLSPDGLPEEQPQTTKLKGKMQSRFDMAE 3815
||.|:|.||:.| ...:...|:|...| .|.....:|.||.|| .||
Fly 4384 LLNEIRMYNIHQGGAGTTSQAASTSGAAAATASYVPTVSGASL---LPNLAVHEGIMQDRF-TAE 4444
Human 3816 NVVIVASQK-RPLGGRELQLPSMSMLTSKTSTQKFFLRVLQVIIQLRDDTRRANKKAKQTGRLGS 3879
:|:|.|.:. :|. .|||||||..|.|.:|.|.:|||.|::.:|:||.....|
Fly 4445 HVIISAPKNAKPT--CELQLPSMKKLMSNSSAQPYFLRTLKIFMQVRDMYEAQN----------- 4496
Human 3880 SGLGSASSIQAAVRQLEAEADAIIQMVREGQRARRQQQAATSESSQSEASVRREESPMDVDQPSP 3944
||.:...:.......: |.||.:..:|..: ..::|:.:...||......||:.:|
Fly 4497 -GLSTGGGVACGAGDND---DDIIDIEGDGGAS----GGSSSDMAPGSASTISPPPPMETNQ--- 4550
Human 3945 SAQDTQSIASDGTPQGEKEKEERP-PEL-------------PLLSEQLSLDELWDMLGECLKELE 3995
||.||....|.:.|.|. |.: |.||:.|.||.||:.|.|||..||
Fly 4551 -------IAQDGDDDEEDDDEARSFPGVGNHAVASASKSTKPTLSQILCLDVLWNTLSECLVALE 4608
Human 3996 ESHDQHAVLVLQPAVEAFFLVHATER-ESKPPVRDTRES-------------------QLAHIKD 4040
||.|:.|||||||.||||||:||:.| .||...|....: ..|....
Fly 4609 ESKDEFAVLVLQPTVEAFFLIHASHRGASKKSGRSFMPNAAGFGLRAAAGAGAIGGLGAAAPSAQ 4673
Human 4041 EPPPLSPAPLTPATPSSLDPFFSREPSSMHISSSLP-------------------PDTQKFLRFA 4086
|..|......:..||||.. |..||.....|::.| .|.||||:||
Fly 4674 EYSPFMDDVSSANTPSSAS--FDDEPRMQDASTNTPLVTNPSTSTAMSAHEAQLRQDRQKFLQFA 4736
Human 4087 ETHRTVLNQILRQSTTHLADGPFAVLVDYIRVLDFDVKRKYFRQELERLDEGLRKEDMAVHVRRD 4151
|.||||||||||||.|||:|||||||||:.|:||||||||||:.||||||||:|:|:..|.|||.
Fly 4737 EKHRTVLNQILRQSPTHLSDGPFAVLVDHTRILDFDVKRKYFQTELERLDEGIRREEHTVSVRRV 4801
Human 4152 HVFEDSYRELHRKSPEEMKNRLYIVFEGEEGQDAGGLLREWYMIISREMFNPMYALFRTSPGDRV 4216
.|||||:|.|:|..|||.|||.|||||.||||||||||||||:|||||:||||||||..||||||
Fly 4802 TVFEDSFRVLYRLGPEEWKNRFYIVFEDEEGQDAGGLLREWYVIISREIFNPMYALFCVSPGDRV 4866
Human 4217 TYTINPSSHCNPNHLSYFKFVGRIVAKAVYDNRLLECYFTRSFYKHILGKSVRYTDMESEDYHFY 4281
||.||||||.|||||||||||||::||||:||:|||||||||||||||||.|::|||||:||.||
Fly 4867 TYMINPSSHANPNHLSYFKFVGRVIAKAVHDNKLLECYFTRSFYKHILGKQVKHTDMESQDYEFY 4931
Human 4282 QGLVYLLENDVSTLGYDLTFSTEVQEFGVCEVRDLKPNGANILVTEENKKEYVHLVCQMRMTGAI 4346
:||.||::||:|||||:||||||||||||.::|||||||.:..||||||.|||.||||::|:|:|
Fly 4932 KGLDYLMKNDISTLGYELTFSTEVQEFGVTQIRDLKPNGRDTAVTEENKFEYVQLVCQLKMSGSI 4996
Human 4347 RKQLAAFLEGFYEIIPKRLISIFTEQELELLISGLPTIDIDDLKSNTEYHKYQSNSIQIQWFWRA 4411
|:||.|||||||:||||.|||||.||||||||||||.|||:|||:|||||||.|.|.||||||||
Fly 4997 RQQLDAFLEGFYDIIPKHLISIFNEQELELLISGLPDIDIEDLKANTEYHKYTSKSAQIQWFWRA 5061
Human 4412 LRSFDQADRAKFLQFVTGTSKVPLQGFAALEGMNGIQKFQIHRDDRSTDRLPSAHTCFNQLDLPA 4476
|||||||||||||||||||||||||||.:|||||||||||||||||||||||.|||||||||||.
Fly 5062 LRSFDQADRAKFLQFVTGTSKVPLQGFGSLEGMNGIQKFQIHRDDRSTDRLPCAHTCFNQLDLPM 5126
Human 4477 YESFEKLRHMLLLAIQECSEGFGLA 4501
|:|::|||..||.||.|||||||.|
Fly 5127 YKSYDKLRSCLLKAIHECSEGFGFA 5151
| 
