DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment LOC100536511 and APE3

DIOPT Version :9

Sequence 1:	XP_021329973.1	Gene:	LOC100536511 / 100536511	-ID:	-	Length:	400	Species:	Danio rerio
Sequence 2:	NP_009845.2	Gene:	APE3 / 852589	SGDID:	S000000490	Length:	537	Species:	Saccharomyces cerevisiae

Alignment Length:	153	Identity:	38/153 - (24%)
Similarity:	64/153 - (41%)	Gaps:	24/153 - (15%)

- Green bases have known domain annotations that are detailed below.

Zfish    44 DVGLSYFDRESNETV---ISMCECGK-------FGINSPLRSASG-LAVLPNSDPLACSKNTTFT 97
            ||.|..|:..|.:.:   :|..|.||       |.::.|:....| |..:||   |.|.:....:
Yeast   133 DVSLQEFEALSGKIISFNLSDAETGKSFANTTAFALSPPVDGFVGKLVEIPN---LGCEEKDYAS 194

Zfish    98 A----SHQPWIALIKTGKCSYTKKINAAQREGASAVVIYNEDGTGNDVILMMYSGADDLVAINIG 158
            .    .::..||||:.|||.:..|.|.|.:.|.:|||||:.:....:.:..............:|
Yeast   195 VVPPRHNEKQIALIERGKCPFGDKSNLAGKFGFTAVVIYDNEPKSKEGLHGTLGEPTKHTVATVG 259

Zfish   159 NILGTQIAYLINNGLDVNMTINV 181
                  :.|.:...|..|:.:|:
Yeast   260 ------VPYKVGKKLIANIALNI 276

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
LOC100536511	XP_021329973.1	PA_GRAIL_like	47..179	CDD:239037	35/146 (24%)
		zf-rbx1	<188..303	CDD:331150
		RING_Ubox	262..308	CDD:327409
APE3	NP_009845.2	M28_SGAP_like	78..506	CDD:349873	38/153 (25%)
APE3	NP_009845.2	PA_ScAPY_like	155..284	CDD:239045	32/131 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000832
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910