DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment LOC100536511 and Rnf150

DIOPT Version :9

Sequence 1:	XP_021329973.1	Gene:	LOC100536511 / 100536511	-ID:	-	Length:	400	Species:	Danio rerio
Sequence 2:	NP_001178022.1	Gene:	Rnf150 / 364983	RGDID:	1304572	Length:	437	Species:	Rattus norvegicus

Alignment Length:	411	Identity:	134/411 - (32%)
Similarity:	197/411 - (47%)	Gaps:	55/411 - (13%)

- Green bases have known domain annotations that are detailed below.

Zfish    19 WLTVLAF--QCCFQLSAAAATFFYWTADVGLSYFDRESNETV----------ISMCECGKFGINS 71
            ||....|  ..|...:.|....:| ||.|.::|.:.||...|          ....|||::|.:|
  Rat    17 WLLSFCFVHLLCLDFTVAEKEEWY-TAFVNITYTEPESGAAVAGGGGGAELHTEKSECGRYGEHS 80

Zfish    72 PLRSASGLAVLPNS--DPLACSKNTTFTA-SH-QPWIALIKTGKCSYTKKINAAQREGASAVVIY 132
            |.:.|.|..|:.:|  |.|||..||.|.| :| :.|||||..|.|:|..||..|..:.||||||:
  Rat    81 PKQDARGEVVMASSVHDRLACDPNTKFAAPAHGKHWIALIPKGNCTYRDKIRNAFLQNASAVVIF 145

Zfish   133 NEDGTGNDVILMMYSGADDLVAINIGNILGTQIAYLINNGLDVNMTINVATPTGVWKGTWAYV-- 195
            |.....|:.|.|.::|.:|:|||.|....|.::..|:...:.|.|.|.:.|     :....||
  Rat   146 NVGSNTNETITMPHAGVEDIVAIMIPEPKGKELVSLLERNVTVTMYITIGT-----RNLQKYVSR 205

Zfish   196 -----LSFTFIGITAVTMFYFAFLFMKRMYINRQLRRQQMEIKRETEKAIGKLEVRTLRTNDPEV 255
                 :|.:||.:..:::.:..|.:::|........|.|..:....:|||.||:|||:|..|.|.
  Rat   206 TSVVFVSISFIVLMIISLAWLVFYYIQRFRYANARDRNQRRLGDAAKKAISKLQVRTIRKGDKET 270

Zfish   256 DSDDTGCVVCTDSYQRGEQVTVLPCRHLYHKKCIEPWLLEHPTCPMCKYNILKS-SIEEDS---Y 316
            :||...|.||.:.|:..:.|.:||||||:||.|::||||:|.||||||.||||: .|..::   .
  Rat   271 ESDFDNCAVCIEGYKPSDVVRILPCRHLFHKSCVDPWLLDHRTCPMCKMNILKALGIPPNADCMD 335

Zfish   317 DQPSPSSSSSSSSSSNDTFCLATITSADQRSTLQSNIQTE---ETAGGHTSDTVNCNLDIHTQHI 378
            |.|.....|.....:|.      ||.|...:..:|::..:   .|.|.             .|.:
  Rat   336 DLPIDFEGSLGGPPTNQ------ITGASDTTVNESSVTLDPAVRTVGA-------------LQVV 381

Zfish   379 YDNPGFEEEPEIIEHQNINQQ 399
            .|.....:|.|.|...|.:|:
  Rat   382 QDPDPAPQEGEAIFTTNSDQE 402

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
LOC100536511	XP_021329973.1	PA_GRAIL_like	47..179	CDD:239037	54/145 (37%)
		zf-rbx1	<188..303	CDD:331150	45/121 (37%)
		RING_Ubox	262..308	CDD:327409	27/45 (60%)
Rnf150	NP_001178022.1	PA_GRAIL_like	45..192	CDD:239037	54/146 (37%)
		UPF0233	<206..>231	CDD:299753	4/24 (17%)
		zf-RING_2	275..318	CDD:290367	23/42 (55%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1487241at2759
OrthoFinder	1	1.000	-	-		FOG0000832
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR22765
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	5.020