DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment LOC100536511 and rnf150

DIOPT Version :9

Sequence 1:	XP_021329973.1	Gene:	LOC100536511 / 100536511	-ID:	-	Length:	400	Species:	Danio rerio
Sequence 2:	NP_001135553.1	Gene:	rnf150 / 100216098	XenbaseID:	XB-GENE-5993052	Length:	427	Species:	Xenopus tropicalis

Alignment Length:	413	Identity:	130/413 - (31%)
Similarity:	196/413 - (47%)	Gaps:	61/413 - (14%)

- Green bases have known domain annotations that are detailed below.

Zfish    19 WLTVLAF--QCCFQLSAAAATFFYWTADVGLSYFDRESNETVISMCECGKFGINSPLRSASGLAV 81
            ||....|  ..|...:.|....:| ||.|.::|.|..|::......|||::|.:|..:.|.||||
Frog    17 WLLSFCFVHLLCLDFTVAEKEEWY-TAFVNITYTDPLSHQWRTEKSECGRYGEHSLKQDAWGLAV 80

Zfish    82 LPNS--DPLACSKNTTFT--ASHQPWIALIKTGKCSYTKKINAAQREGASAVVIYN-EDGTGNDV 141
            :|:|  |.|||...|.|:  |:...|:|||..|.|:|..||..|..:.||||:||| .....|:.
Frog    81 MPSSPQDRLACDPATKFSVPANASRWVALIPKGNCTYRDKIKHAALQNASAVLIYNVGSSNANET 145

Zfish   142 ILMMYSGADDLVAINIGNILGTQIAYLINNGLDVNMTINVATPTGVWKGTWAYV-------LSFT 199
            |.|.:.|.:|:|||.|....|.:||.|:...::|.:.|.:.|     :....||       :|.:
Frog   146 ITMPHPGIEDIVAIMIPEPKGREIATLLERNINVTIYITIGT-----RNLQKYVSRTSVVFVSIS 205

Zfish   200 FIGITAVTMFYFAFLFMKRMYINRQLRRQQMEIKRETEKAIGKLEVRTLRTNDPEVDSDDTGCVV 264
            ||.:..:::.:..|.:::|........|.|..:....:|||.||:|||::..|.|.:.:...|.|
Frog   206 FIVLMIISLAWLVFYYIQRFRYANARDRNQRRLGDAAKKAISKLQVRTIKKGDKETEPEFDNCAV 270

Zfish   265 CTDSYQRGEQVTVLPCRHLYHKKCIEPWLLEHPTCPMCKYNILKS---SIEEDSYDQPSPSSSSS 326
            |.:.|:..:.|.:||||||:||.|::||||:|.||||||.||||:   ....|..|...|....|
Frog   271 CIEGYKPNDVVRILPCRHLFHKSCVDPWLLDHRTCPMCKMNILKALGIPPNADCLDDIPPDFEGS 335

Zfish   327 SSSSSNDTFCLATITSADQRSTLQSNIQTE---ETAG--------------GHTSDTVNCNLDIH 374
            ....:|.      ||.|...:..:|::..:   .|.|              |..|.|.:.
Frog   336 VGPPTNQ------ITGASDVTVNESSVGIDPSVRTVGVLQVIQDAESLPQVGEVSYTASS----- 389

Zfish   375 TQHIYDNPGFEEEPEIIEHQNIN 397
                      |:||.:....:|:
Frog   390 ----------EQEPAVSSDSDIS 402

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
LOC100536511	XP_021329973.1	PA_GRAIL_like	47..179	CDD:239037	53/136 (39%)
		zf-rbx1	<188..303	CDD:331150	42/121 (35%)
		RING_Ubox	262..308	CDD:327409	27/45 (60%)
rnf150	NP_001135553.1	PA_GRAIL_like	45..183	CDD:239037	53/137 (39%)
		UPF0233	<197..>222	CDD:299753	4/24 (17%)
		zf-RING_2	266..309	CDD:290367	23/42 (55%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1487241at2759
OrthoFinder	1	1.000	-	-		FOG0000832
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR22765
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	5.020