Protein Alignment RBM14-RBM4 and nab3

DIOPT Version :9

• Sequence 1: NP_001185774.1
• Gene: RBM14-RBM4 / 100526737
• HGNCID: 38840
• Length: 339
• Species: Homo sapiens
• Sequence 2: NP_593002.1
• Gene: nab3 / 2543638
• PomBaseID: SPAC3H8.09c
• Length: 738
• Species: Schizosaccharomyces pombe
• Alignment Length: 407
• Identity: 71/407 - (17%)
• Similarity: 127/407 - (31%)
• Gaps: 141/407 - (34%)

Human     2 KIFVGNVDGADTTPEELAALFAPYGTVMSCAVMKQFAFVHMRENAGALRAIEALHGHELRPGRAL 66
            ::|:|:::....:...|..:|..||.:....:...:.||....|....||:.|..|:.:| |:.|
pombe   364 RLFLGHLNTKSLSKRNLWKVFKIYGPLAQIVLKANYGFVQFFTNEDCARALNAEQGNFVR-GQKL 427

Human    67 VVEMSRPR-----------------PLNTWKIFVGNVSAACTSQE-LRS-------LFERRGRVI 106
            .:|:|:.:                 ..|.:...:||:....:|:: .||       .::|:|.:.
pombe   428 HLEISKIQKKYQNQIENMKKGSHVTKSNQYSEMIGNLPYPTSSRKRTRSPLMSKGKSYDRKGSIS 492

Human   107 -------ECDVVKGKRMHVQLSTSRLRTAPGMGDQSGCYRCGKEGHWSKECPIDRSGRVADLTEQ 164
                   :|:::..:                        .|.||..|..|............|..
pombe   493 MSKNFSPDCEILVTE------------------------DCPKEFVWGVEKVFQERRLNIHTTCL 533

Human   165 YNEQ----------YGAVRTPYTMSYG-----------------DSLYYNNAYGALDAYYKRC-- 200
            |.:.          ..:|::...::.|                 ||....:.|.|:|......
pombe   534 YRDSNLQVIIKSCIINSVKSIILINAGLAHLGKVSVQVFKDGSSDSEVRCDEYAAVDVMVAASIV 598

Human   201 -RAARSYEAVAAAAASVYNYAEQTLSQLPQ---------------------------VQNT-AMA 236
             .|..|....||::...|| .|:.:..:|.                           :||| :..
pombe   599 HHAKTSLMHSAASSTPSYN-GERIVPDVPSPCISTNPNLPALVGSLDSVNLHHLLGFIQNTYSTT 662

Human   237 SHL-TSTSLDPYDRHLLPTSGAAATAAAAAAAAAAVTAASTSYYGRDRSPLRRATAPVPTVGEGY 300
            |:: |..|.:|.|     |.|:..|   ..:.:..|.......|.||                .|
pombe   663 SYIPTRVSFNPND-----TGGSFGT---ITSQSQFVVNEMPKNYARD----------------NY 703

Human   301 GYGHESELSQASAAARN 317
            ...|..|..|.|:.|.|
pombe   704 EALHSQESRQRSSVAGN 720

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RBM14-RBM4	NP_001185774.1	RRM1_CoAA	1..71	CDD:241052	17/68 (25%)
		RRM_SF	79..>113	CDD:302621	8/48 (17%)
		ZnF_C2HC	136..151	CDD:197667	5/14 (36%)
nab3	NP_593002.1	RRM	256..503	CDD:223796	27/139 (19%)
		RRM_Nab3p	364..434	CDD:240788	18/70 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	40	1.000	Domainoid score	I4211
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000