DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment RBM14-RBM4 and rsd1

DIOPT Version :9

Sequence 1:	NP_001185774.1	Gene:	RBM14-RBM4 / 100526737	HGNCID:	38840	Length:	339	Species:	Homo sapiens
Sequence 2:	NP_594422.2	Gene:	rsd1 / 2542545	PomBaseID:	SPAC19G12.07c	Length:	603	Species:	Schizosaccharomyces pombe

Alignment Length:	219	Identity:	48/219 - (21%)
Similarity:	80/219 - (36%)	Gaps:	64/219 - (29%)

- Green bases have known domain annotations that are detailed below.

Human     2 KIFVGNVDGADTTPEELAALFAPYGTVMSCAVM-------KQFAFVHMRENAGALRAIEALHGHE 59
            ::.|.|:. .:.|.|::.|:|.|:|.:....:.       |.|.::..|....|..|:|.::|.:
pombe   341 RLCVSNIH-FNLTDEDVKAIFEPFGDIEFVHLQRDDQNRSKGFGYIQYRNPISARNALEKMNGFD 404

Human    60 LRPGRALVV--------------------------EMSRPRPLNTWKIFVGNVSAACTSQELR-- 96
            | .||.:.|                          |.|:|...|       ..|:...||:.|
pombe   405 L-AGRNMRVCLGNDKFTTETTSSMLKRFDETLARQERSQPSQRN-------GGSSTYESQDYREA 461

Human    97 ---SLFERRGRVIECDVVKGK--RMHVQLSTSRLRTAPGMGDQSGC------YRCGKE--GHWSK 148
               |..|...|.|..|.:..|  |.......|:|.:.|....:|.|      :...:|  .:|.:
pombe   462 APLSPTEEESRPITRDELMKKLARSEDISDNSKLVSEPEPPIRSRCALLENMFNPAEETSPNWVQ 526

Human   149 ECPIDRSGRVADLTEQYNEQYGAV 172
            |..       .|:.|:.:|:||.|
pombe   527 ELE-------QDVKEECDEKYGKV 543

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
RBM14-RBM4	NP_001185774.1	RRM1_CoAA	1..71	CDD:241052	20/101 (20%)
		RRM_SF	79..>113	CDD:302621	9/38 (24%)
		ZnF_C2HC	136..151	CDD:197667	4/22 (18%)
rsd1	NP_594422.2	RRM1_RBM39_like	241..313	CDD:240729
		RRM2_RBM23_RBM39	342..413	CDD:240730	18/72 (25%)
		RBM39linker	476..523	CDD:292157	9/46 (20%)
		RRM3_RBM39_like	505..589	CDD:240731	11/46 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910