DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment MSANTD3-TMEFF1 and tmeff1

DIOPT Version :9

Sequence 1:	NP_001185741.1	Gene:	MSANTD3-TMEFF1 / 100526694	HGNCID:	38838	Length:	454	Species:	Homo sapiens
Sequence 2:	NP_001093738.2	Gene:	tmeff1 / 100101772	XenbaseID:	XB-GENE-876375	Length:	372	Species:	Xenopus tropicalis

Alignment Length:	319	Identity:	254/319 - (79%)
Similarity:	293/319 - (91%)	Gaps:	1/319 - (0%)

- Green bases have known domain annotations that are detailed below.

Human   137 SAQELNVRESDV-RVCDESSCKYGGVCKEDGDGLKCACQFQCHTNYIPVCGSNGDTYQNECFLRR 200
            :..||::|||:| ||||||:|||||||||:||.|||.|||||.|||.||||||||||||||||||
Frog    54 NCSELSLRESEVRRVCDESTCKYGGVCKEEGDVLKCICQFQCQTNYAPVCGSNGDTYQNECFLRR 118

Human   201 AACKHQKEITVIARGPCYSDNGSGSGEGEEEGSGAEVHRKHSKCGPCKYKAECDEDAENVGCVCN 265
            :|||.||||||:|||||:||..|||||||.||||.|||:||||||.||:.||||||||:||||||
Frog   119 SACKQQKEITVVARGPCFSDIASGSGEGEYEGSGGEVHKKHSKCGNCKFGAECDEDAEDVGCVCN 183

Human   266 IDCSGYSFNPVCASDGSSYNNPCFVREASCIKQEQIDIRHLGHCTDTDDTSLLGKKDDGLQYRPD 330
            |||||::||||||:|||||:|||.||||||::|||||::||..|.:||:||::||||:|:|.||:
Frog   184 IDCSGHNFNPVCATDGSSYSNPCLVREASCLRQEQIDVKHLRSCIETDETSIMGKKDEGIQNRPE 248

Human   331 VKDASDQREDVYIGNHMPCPENLNGYCIHGKCEFIYSTQKASCRCESGYTGQHCEKTDFSILYVV 395
            |||::||||..::||::||.||.||||:|||||..||||||||||:||||||:|:||||:|||||
Frog   249 VKDSTDQREGDFMGNYIPCSENYNGYCVHGKCELSYSTQKASCRCDSGYTGQYCDKTDFNILYVV 313

Human   396 PSRQKLTHVLIAAIIGAVQIAIIVAIVMCITRKCPKNNRGRRQKQNLGHFTSDTSSRMV 454
            ||||||||||||||||||||||||||||||||||||||||||||||||||:||.|||||
Frog   314 PSRQKLTHVLIAAIIGAVQIAIIVAIVMCITRKCPKNNRGRRQKQNLGHFSSDASSRMV 372

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
MSANTD3-TMEFF1	NP_001185741.1	Myb_DNA-bind_5	9..83	CDD:290584
		KAZAL	173..217	CDD:197624	38/43 (88%)
		KAZAL	263..309	CDD:197624	35/45 (78%)
		PHA02887	<349..385	CDD:165214	28/35 (80%)
tmeff1	NP_001093738.2	KAZAL	90..135	CDD:197624	38/44 (86%)
		KAZAL	181..227	CDD:197624	35/45 (78%)
		PHA02887	<267..303	CDD:165214	28/35 (80%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	247	1.000	Domainoid score	I12067
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	584	1.000	Inparanoid score	I6639
NCBI	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG38610
OrthoDB	1	1.010	-	-		D175799at32523
OrthoFinder	1	1.000	-	-		FOG0011351
OrthoInspector	1	1.000	-	-		oto148294
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X8989
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	9	8.980