Protein Alignment SLC17A4 and dmGlut

DIOPT Version :9

• Sequence 1: NP_005486.1
• Gene: SLC17A4 / 10050
• HGNCID: 10932
• Length: 497
• Species: Homo sapiens
• Sequence 2: NP_620115.2
• Gene: dmGlut / 47253
• FlyBaseID: FBgn0010497
• Length: 496
• Species: Drosophila melanogaster
• Alignment Length: 456
• Identity: 130/456 - (28%)
• Similarity: 221/456 - (48%)
• Gaps: 23/456 - (5%)

Human    39 LALILQLCNFSIYTQQMNLSIAIPAMV---NNTAPPSQPNASTERPSTDSQGYWNETLKEFKAMA 100
            ||::..|...:.||.::.||.||..:|   |:|...|:  |..|....|          |..::.
  Fly    23 LAIMGFLAILNAYTMRVCLSQAITVLVVKKNSTDDDSE--AICEPDDID----------EGTSVG 75

Human   101 PAYDWSPEIQGIILSSLNYGSFLAPIPSGYVAGIFGAKYVVGAGLFISSFLTLFIPLAANAGVA- 164
            ..::||.|:||:||||...|..:..||.|.:|..||.|:.:|.|:..::..|:..|||.|.|.:
  Fly    76 GDFEWSEELQGLILSSFYIGYIVTHIPGGLLAEKFGGKWTLGLGILSTAVFTMLTPLAINKGDSD 140

Human   165 LLIVLRIVQGIAQVMVLTGQYSIWVKWAPPLERSQLTTIAGSGSMLGSFIVLLAGGLLCQTIGWP 229
            .|||.|::.|:.:.........:...|.|..||.:|..:...|..:|:.:..|..|:.....||.
  Fly   141 WLIVTRVLMGLGEGTTFPALSVLLAAWVPANERGKLGALVLGGGQVGTIMGNLLSGVFIDAYGWE 205

Human   230 YVFYIFGGIGCACCPLWFPLIYDDPVNHPFISAGEKRYIVCSLA----QQDCSPGWSLPIRAMIK 290
            :|||.|||:|.....::..|.|.||.:||||...|:.|:|..:.    .:|..|   .|.:|::.
  Fly   206 FVFYFFGGLGVVWFAIFMFLCYSDPTSHPFIKPSEREYLVKEIGTISRNEDLPP---TPWKAILT 267

Human   291 SLPLWAILVSYFCEYWLFYTIMAYTPTYISSVLQANLRDSGILSALPFVVGCICIILGGLLADFL 355
            :||::|::.:.....|.||.::...|.|::.|||.:::.:|:.|:||:|:..|..:..|.:||::
  Fly   268 NLPMFALVAAQIGHDWGFYIMVTDLPKYMADVLQFSIKANGLYSSLPYVMMWIVSVGSGFVADWM 332

Human   356 LSRKILRLITIRKLFTAIGVLFPSVILVSLPWVRSSHSMTMTFLVLSSAISSFCESGALVNFLDI 420
            :.|.:|.....||:.|.:....|::.:|...:......:.:....:...:.....:|..::.||:
  Fly   333 IRRGVLSTTNTRKVMTGLAAFGPAIFMVGASYAGCDRVLVVVLFTICMGLMGAYYAGMKLSPLDM 397

Human   421 APRYTGFLKGLLQVFAHIAGAISPTAAGFFISQDSEFGWRNVFLLSAAVNISGLVFYLIFGRADV 485
            :|.|.|.|..:......|.|.|:|...|......|...||.||.::..|.....|.|.|:...:|
  Fly   398 SPNYAGTLMAITNGIGAITGVITPYLVGVMTPNASLLEWRLVFWVAFGVLCFTAVIYCIWASGEV 462

Human   486 Q 486
            |
  Fly   463 Q 463

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC17A4	NP_005486.1	UhpC	30..491	CDD:332119	130/456 (29%)
dmGlut	NP_620115.2	2A0114euk	25..463	CDD:129972	126/452 (28%)
		MFS	77..458	CDD:119392	111/383 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165148635
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2532
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.740