Protein Alignment hspa8 and Hsc70-4

DIOPT Version :9

• Sequence 1: XP_002937574.2
• Gene: hspa8 / 100496320
• XenbaseID: XB-GENE-955426
• Length: 646
• Species: Xenopus tropicalis
• Sequence 2: NP_001262586.1
• Gene: Hsc70-4 / 41840
• FlyBaseID: FBgn0266599
• Length: 651
• Species: Drosophila melanogaster
• Alignment Length: 652
• Identity: 556/652 - (85%)
• Similarity: 598/652 - (91%)
• Gaps: 7/652 - (1%)

 Frog     1 MSKGPAVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPTN 65
            |||.||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||.
  Fly     1 MSKAPAVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPTQ 65

 Frog    66 TVFDAKRLIGRRFEDAVVQSDMKHWPFNVISDSGRPKVQVEYKAETKSFYPEEISSMVLVKMKEI 130
            |:|||||||||:|:||.||||||||||.|:|..|:||::|.||.|.|:|:|||||||||.||||.
  Fly    66 TIFDAKRLIGRKFDDAAVQSDMKHWPFEVVSADGKPKIEVTYKDEKKTFFPEEISSMVLTKMKET 130

 Frog   131 AEAYLGKTVTNAVITVPAYFNDSQRQATKDAGTISGLNVLRIINEPTAAAIAYGLDKKVGAERNV 195
            ||||||||||||||||||||||||||||||||||:|||||||||||||||||||||||...||||
  Fly   131 AEAYLGKTVTNAVITVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYGLDKKAVGERNV 195

 Frog   196 LIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVNHFVAEFKRKHKKDIIDNKRAV 260
            |||||||||||||||:|:|||||||||||||||||||||||:|.|||.|||||||||:..||||:
  Fly   196 LIFDLGGGTFDVSILSIDDGIFEVKSTAGDTHLGGEDFDNRLVTHFVQEFKRKHKKDLTTNKRAL 260

 Frog   261 RRLRTACERAKRTLSSSTQASIEIDSLYEGIDFYTSITRARFEELNADLFRGTLDPVEKALRDAK 325
            |||||||||||||||||||||||||||:||.||||||||||||||||||||.|:|||||||||||
  Fly   261 RRLRTACERAKRTLSSSTQASIEIDSLFEGTDFYTSITRARFEELNADLFRSTMDPVEKALRDAK 325

 Frog   326 LDKSQIHDIVLVGGSTRIPKIQKLLQDFFNGKELNKSINPDEAVAYGAAVQAAILSGDKSENVQD 390
            ||||.|||||||||||||||:|:||||.|||||||||||||||||||||||||||.||||:.|||
  Fly   326 LDKSVIHDIVLVGGSTRIPKVQRLLQDLFNGKELNKSINPDEAVAYGAAVQAAILHGDKSQEVQD 390

 Frog   391 LLLLDVTPLSLGIETAGGVMTVLIKRNTTIPTKQTQTFTTYSDNQPGVLIQVYEGERAMTKDNNL 455
            ||||||||||||||||||||:||||||||||||||||||||||||||||||||||||||||||||
  Fly   391 LLLLDVTPLSLGIETAGGVMSVLIKRNTTIPTKQTQTFTTYSDNQPGVLIQVYEGERAMTKDNNL 455

 Frog   456 LGKFELTGIPPAPRGVPQIEVTFDIDANGILNVSAVDKSTGKENKITITNDKGRLSKEDIERMVQ 520
            ||||||:||||||||||||||||||||||||||:|:::||.|||||||||||||||||||||||.
  Fly   456 LGKFELSGIPPAPRGVPQIEVTFDIDANGILNVTALERSTNKENKITITNDKGRLSKEDIERMVN 520

 Frog   521 EAEKYKAEDEKQRDKVSSKNSLESYAFNMKATVEDEKLKGKISDEDKQKILDKCNEVISWLDKNQ 585
            |||||:.|||||::.:::||.||||.||||||::::.||.||||.|:..|||||||.|.|||.||
  Fly   521 EAEKYRNEDEKQKETIAAKNGLESYCFNMKATLDEDNLKTKISDSDRTTILDKCNETIKWLDANQ 585

 Frog   586 TAEKEEFEHQQKELEKVCNPIITKLYQSA----GGMPGGMPGGFPGAGGA--PSGGASSGPTIEE 644
            .|:|||:||:|||||.|||||||||||.|    |||||| |||.|||.||  .:|...:||||||
  Fly   586 LADKEEYEHRQKELEGVCNPIITKLYQGAGFPPGGMPGG-PGGMPGAAGAAGAAGAGGAGPTIEE 649

 Frog   645 VD 646
            ||
  Fly   650 VD 651

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
hspa8	XP_002937574.2	PTZ00009	1..613	CDD:240227	531/611 (87%)
Hsc70-4	NP_001262586.1	PTZ00009	1..612	CDD:240227	530/610 (87%)
		HSPA1-2_6-8-like_NBD	6..381	CDD:212675	334/374 (89%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	1042	1.000	Domainoid score	I28
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	1104	1.000	Inparanoid score	I236
OMA	1	1.010	-	-		QHG53894
OrthoDB	1	1.010	-	-		D180577at33208
OrthoFinder	1	1.000	-	-		FOG0000049
OrthoInspector	1	1.000	-	-		otm48923
Panther	1	1.100	-	-	LDO	PTHR19375
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X148
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	10	10.080