Protein Alignment pak3 and Pak

DIOPT Version :10

• Sequence 1: XP_004916907.1
• Gene: pak3 / 100495025
• XenbaseID: XB-GENE-961764
• Length: 556
• Species: Xenopus tropicalis
• Sequence 2: NP_001138013.2
• Gene: Pak / 44039
• FlyBaseID: FBgn0267698
• Length: 840
• Species: Drosophila melanogaster
• Alignment Length: 848
• Identity: 367/848 - (43%)
• Similarity: 436/848 - (51%)
• Gaps: 313/848 - (36%)

 Frog     8 EEKPPAPPLRMNSN---NRDSSA----------------LNHCSKPLPMAPEEKNKKARLRSIFP 53
            |:||||||:|:.||   |..|..                :....:|||..|::.::|
  Fly     5 EDKPPAPPVRLTSNRGGNERSGGGVGVGGGGLGGGGMGDVPPDMRPLPKEPDDSDRK-------- 61

 Frog    54 GGGDKTNKKKEK--------ERPEISLPSDFEHTIHVGFDAVTGEFTGIPEQWARLLQTSNITKL 110
               .||.|.|.|        .:|.||.|::||||:|||||||||||||:||.|||||..|||:|.
  Fly    62 ---KKTLKSKIKGSKPSHTDSKPNISYPTNFEHTVHVGFDAVTGEFTGMPEAWARLLMNSNISKQ 123

 Frog   111 EQKKNPQAVLDVLKFYDSKETVN-NQKYM--------------------SFTSGDKSAHGYIAAH 154
            ||||||||||||||::|:..... :.|||                    |.|..|...||..:..
  Fly   124 EQKKNPQAVLDVLKWFDNTTKQRPSSKYMTNAITTHSGSSLSRVSSSSPSSTPTDSELHGSNSGG 188

 Frog   155 SLF------------------------------LSHVLQN----------------AKTASEPPL 173
            :|.                              ..|:||.                :::.|...:
  Fly   189 NLIGVQLGSMTLGPNANNVAVAGQILGNHYQQQQQHLLQQQQPLLHQNHNQHHMGISQSHSYNFV 253

 Frog   174 APPVSEEEDEEEEEEEDD---------NEPPPVIAPRPEHTKSIYTRSV--IEPVALTAPAKEAS 227
            ...||....:.....|||         ..|||.:|.|||.|||||||.:  ::|..:..|...|
  Fly   254 GHTVSSSTSQHSSANEDDMLGPQHPQQQPPPPPVASRPERTKSIYTRPIEDLQPAIIPMPVAPA- 317

 Frog   228 TSPVTP---------------QPENSNSSTSTLYRN----------------------------- 248
            |:|.||               .|...|::|:||.:|
  Fly   318 TTPATPLQNHRTPGGISAPAASPMMHNNATTTLDKNKNNATPTSPTTTKTTAETEGTDATSTLLS 382

 Frog   249 -----------TD---------------------------------------------------- 250
                       ||
  Fly   383 ATNPSCSTTPTTDPAPAAPRGSLVETATAHATTAAATVATSTTTNHHSSASSFSSFPSFHDDDGT 447

 Frog   251 ----------------------------------------------------------------- 250
                                                                             
  Fly   448 HHALPTIHCPTPTSSSRNSTVSFPVAVPLPPIVTPASPTPASIESPDLYTPEPTVAQVSAGGPSS 512

 Frog   251 ------------------------RQRKKSKMTDEEILEKLRSIVSVGDPKKKYTRFEKIGQGAS 291
                                    ...||.||:|||||||||:|||||||.:|||:.||||||||
  Fly   513 QVAGNQIAVPQAAVAPAATPNTRAANAKKKKMSDEEILEKLRTIVSVGDPNRKYTKMEKIGQGAS 577

 Frog   292 GTVYTAIDIATGQEVAIKQMNLQQQPKKELIINEILVMRENKNPNIVNYLDSYLVGDELWVVMEY 356
            |||||||:.:||.|||||||||.|||||||||||||||||||:||:|||||||||.:||||||||
  Fly   578 GTVYTAIESSTGMEVAIKQMNLSQQPKKELIINEILVMRENKHPNVVNYLDSYLVSEELWVVMEY 642

 Frog   357 LAGGSLTDVVTETCMDEGQIAAVCRECLQALDFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFC 421
            |.||||||||||||||||||||||||.||||:|||:||||||||||||||||:||||||||||||
  Fly   643 LPGGSLTDVVTETCMDEGQIAAVCREVLQALEFLHANQVIHRDIKSDNILLGLDGSVKLTDFGFC 707

 Frog   422 AQITPEQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLI 486
            |||:||||||:|||||||||||||||||.||||||:|||||||||||||||||||||||:|||||
  Fly   708 AQISPEQSKRTTMVGTPYWMAPEVVTRKQYGPKVDLWSLGIMAIEMVEGEPPYLNENPLKALYLI 772

 Frog   487 ATNGTPELQNPERLSAIFRDFLNRCLEMDVDRRGSAKELLQHPFLKLAKPLSSLTPLIIAAKEAI 551
            ||||.||::..::||:.|:|||::|||::||||.||.:||:|||||||:||:||||||:|||||.
  Fly   773 ATNGKPEIKEKDKLSSAFQDFLDQCLEVEVDRRASALDLLKHPFLKLARPLASLTPLIMAAKEAT 837

 Frog   552 KNS 554
            |.:
  Fly   838 KGN 840

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pak3	XP_004916907.1	PBD	69..126	CDD:395634	45/56 (80%)
		STKc_PAK3	260..556	CDD:132987	247/295 (84%)
Pak	NP_001138013.2	PBD	83..139	CDD:395634	45/55 (82%)
		STKc_PAK_I	558..818	CDD:270814	218/259 (84%)