Protein Alignment mast3 and dop

DIOPT Version :10

• Sequence 1: XP_031761059.1
• Gene: mast3 / 100494808
• XenbaseID: XB-GENE-5928376
• Length: 1492
• Species: Xenopus tropicalis
• Sequence 2: NP_648778.1
• Gene: dop / 39686
• FlyBaseID: FBgn0267390
• Length: 2139
• Species: Drosophila melanogaster
• Alignment Length: 1860
• Identity: 685/1860 - (36%)
• Similarity: 896/1860 - (48%)
• Gaps: 525/1860 - (28%)

 Frog    59 NRKSLVVGSPSPTL---SRPLSPLSVPTAGSSPLDSPRNFSTSASVNFPFARSHGPRADRADGRR 120
            :|.|||..|.:...   ||..||.|     :||:||||..|.......|..|....|...|||||
  Fly   317 HRLSLVTNSAAVAAAGGSRTHSPYS-----ASPVDSPRLNSPMPFAFAPIKRIASCRGVVADGRR 376

 Frog   121 WSLASLPSSGYGTNTPSSTLSSSSSSQERLHQL-------------------------------- 153
            ||:||||||||||...||.|||..||||.|:||
  Fly   377 WSVASLPSSGYGTTPGSSNLSSQCSSQEGLNQLAHNIPPGVQEADAAAVAAGACCAEHLKQHCPK 441

 Frog   154 ----------------PFQPT---------------ADELHFL--------------SKHFRSTE 173
                            |.:||               ..||...              |....|..
  Fly   442 HCALLLAVSQKQLTPQPPKPTQLQPQKSMTAACVNCCAELSVTCGGQQAGGGAANGGSSANSSGS 506

 Frog   174 SITDEDGRRSPCMRPRSRSLSPGRASSNFDNEIIMMNHVYKERFPKATAQMEERLQDIITH---- 234
            |.....||.||..||||||||....|...||||.:||.:|||||||||.||||||:..|..
  Fly   507 SAMQVGGRMSPYFRPRSRSLSSPSRSPIVDNEIAVMNTLYKERFPKATQQMEERLKLFINENKSA 571

 Frog   235 ----FCPSQTLPLADGVLGFIHHQIIELARDCLDKSKGALITSRYFLELQEKLEKMLQDAHNRSE 295
                |..||.      ::.|:|||::|:|||||.||:..||||:||.||.|.||::|.:...:|
  Fly   572 ACNSFRDSQP------IVRFVHHQVLEMARDCLHKSEAKLITSQYFYELSENLERLLVETKEKS- 629

 Frog   296 SEEVMFTNHLARKLLMVIARPARLLECLEFDPEQFYHLLEAAEGQAKVGQGIKTDIPRYIINQLG 360
            .|.....|.:.:|||::|:|||||||||||||::||.|||||||.||....||.|||:|||::||
  Fly   630 PEAAAELNGVIKKLLLIISRPARLLECLEFDPQEFYELLEAAEGHAKAMPVIKADIPQYIIHKLG 694

 Frog   361 LTKDPLEEIVQLDHYDTE---------------------------------SSLLLD-------- 384
            |.:||:.|: |.:..:|:                                 |||.||
  Fly   695 LNRDPIAEL-QQELRETQQMCSEQVTVDADPLHPGGSLLLNSPLTSAAKQLSSLALDAIAMDSGS 758

 Frog   385 -----QEDYQDPCIS--STPS-------------------------------------------- 398
                 |:..|.|..:  :.||
  Fly   759 GTATPQQPPQTPVATCDTAPSFALAISQMNEEKGGSSSAVGGGSSSKVAGAEGITGGSAATATGS 823

 Frog   399 ---RKKPCESDFETIKLISNGAYGAVYLVRHKEMRQRFAMKKINKQNLILRNQIQQVFVERDILT 460
               :..|.|:||:.:||||||||||||||:||..|||||||||||.|||||||::|||.|||||:
  Fly   824 GAQQPSPQENDFDIVKLISNGAYGAVYLVKHKTTRQRFAMKKINKNNLILRNQVEQVFAERDILS 888

 Frog   461 FAENPFVVSMFCSFETRRHLCMVMEYVEGGDCATLLKNMGPLPVDMSRMYFAETVLALEYLHNYG 525
            ||:|||||||:|||||::|||:||||||||||.|||||:||||.||:|.||||||||:||||:||
  Fly   889 FADNPFVVSMYCSFETKKHLCLVMEYVEGGDCGTLLKNIGPLPADMARFYFAETVLAVEYLHSYG 953

 Frog   526 IVHRDLKPDNLLITSLGHIKLTDFGLSKIGLMNMTTNLYEGHIEKDTREFLDKQVCGTPEYIAPE 590
            ||||||||||||||:|||||||||||||:|||::.||||||:|:.:||:|.||||.|||||||||
  Fly   954 IVHRDLKPDNLLITALGHIKLTDFGLSKMGLMSLATNLYEGYIDSETRQFSDKQVYGTPEYIAPE 1018

 Frog   591 VILRQGYGKPVDWWAMGIILYEFLVGCVPFFGDTPEELFGQVISDEIIWPGGEE-ALPTDAQDLI 654
            ||||||||||||||:|||||||||:|||||||:|.||||...::|:|.||..|: .:..:|:|:|
  Fly  1019 VILRQGYGKPVDWWSMGIILYEFLIGCVPFFGETTEELFAHTVNDDIEWPDSEDWPVQAEAKDII 1083

 Frog   655 TRLLRQNPLERLGT-GGAQEVKQHTFFLPLDWNGLLRQKAEFVPQLEAEDDTSYFDTRSERYHHL 718
            ::||:|||.:|||| .||.|:|:|.:||.:|||.||||||||||||..:|||||||||.:||:|.
  Fly  1084 SQLLQQNPRDRLGTQSGALEMKEHEYFLGMDWNSLLRQKAEFVPQLSHDDDTSYFDTRMDRYNHD 1148

 Frog   719 ASEEDEETNDDESSVEIRQFSSCSHRFSKV-YSSSEHLATQLNLSFS--------STERSHSDEK 774
            ...||  |:|.:.:.....|:|.:.::.|. ||.|.| ||..:...:        |:..|.:.|.
  Fly  1149 LGGED--TDDTDDTPVFGSFNSYTPQYRKQHYSWSRH-ATPTSTDGAKPTGPPPLSSLPSRAQET 1210

 Frog   775 EEHSDRWERTLSIEEEKNRLGPENRLRSWTSSGSSHHSWLSER------------SASPNVLTST 827
            ...:.....|.::.:.|:.:|..:...|.:.|||:.|..:..:            |:|...:.||
  Fly  1211 PAATVGATSTGALPKLKSGMGSGSGSGSGSGSGSASHDGVVNKFLNTPQLRKLDLSSSCLKVPST 1275

 Frog   828 CSLDTMPKFAFS------SEEESSDHKPERP-----------------TFTLGEMKGTPPKPTSL 869
            ...|.:|:...:      :|.....|..::|                 |.|:.....||| ||..
  Fly  1276 PDADYLPELLHNVTIGNDAELRMLKHYLQQPNPGATQRMQQRHSMPPNTTTIISTPATPP-PTQT 1339

 Frog   870 ---------CADIVSLSRTRLRSNSTGAKNSTPRPLEAGVTRRLRG--------------QRDTP 911
                     .|.:.|.||:...|:.|.:.:.:|:     :.|:.:|              :.:|.
  Fly  1340 QATMAATPPTATVGSFSRSTPESSQTDSDDFSPQ-----INRKRKGVCARDILPRFSISIEDETI 1399

 Frog   912 EKHSSST--------------------------GSRVP--------KSASVSALSLIITADDFGS 942
            ...||||                          ||.|.        ||||...|||:.:.|:...
  Fly  1400 SAGSSSTENMNLPREQSPLALQHQPKSMDGSTSGSSVKHHRSRSIVKSASALGLSLMTSLDNSQL 1464

 Frog   943 GS----LASPISPRSLSSNPSSRDSSPSRESTVAVSSLRPPIIIHSSGKKYGFTLRAIRVYMGES 1003
            .:    :.||....:.||..||||:||.||.:..|::|:|||||....:.:|||:..||||.|::
  Fly  1465 AAQLCGIQSPGGGGNGSSTASSRDTSPCRELSPLVTNLKPPIIIRRGPRGFGFTVHTIRVYYGDT 1529

 Frog  1004 DVYTVHHMVWSIEDGSPAHEAGLRAGDLITHVNGESVLGLVHMDVVELLLKSGSKVSLRTTPLEN 1068
            |.||:||:|.::::||||.|||||..|||||||||:|.||.|..|::|||..|..|:||.||||:
  Fly  1530 DFYTMHHLVMAVDEGSPAFEAGLRPADLITHVNGEAVQGLFHTQVLQLLLSGGEHVTLRATPLEH 1594

 Frog  1069 TSIKIGPARKNSCKGRMAR----RTKKSRKRE-SQDRKRSLFKKISKQ--------------STV 1114
            |||:.|..:::..:.::|:    |.||..||| .:.||.|||::||.:              |..
  Fly  1595 TSIQSGGRKRDLMQSKLAKKGVNRQKKQTKREHDKKRKTSLFRRISSKRANAEMQQYSAGTSSPT 1659

 Frog  1115 LQTSRSFS---SGLH----QSLSSSESLPASPTHSLSPGPTTPSRSPAPDAAGDAAS-------- 1164
            ..::|:.|   |..|    ||.::|.|...||:   |..|.||:.|...:..|:|.|
  Fly  1660 TPSARNLSPLDSSYHSSCCQSAANSSSQSTSPS---SSSPNTPTGSSGSNHGGNAGSVAVAPSAL 1721

 Frog  1165 ----PQSTSP-------------------CSSTPSSPAGHI-----RPSSLQCLTPKLSGQRYKV 1201
                |.:..|                   ..:.|.||.|.:     |||:|..|..||......:
  Fly  1722 SVQLPSAPPPTQLVLLPHVGAVVGSNPTSVGNVPVSPTGVVPQLYQRPSTLHGLKHKLHAATAVI 1786

 Frog  1202 -------------------------GRRKSTSSIPPSPLACTPSPVPQAPSSPQRSPSPLLPSHP 1241
                                     .||||...||.||||.||||.| .||||.||||||  :.|
  Fly  1787 AGGGNANNPAGGLKTLHTTNNNSLPNRRKSVGHIPLSPLARTPSPSP-LPSSPTRSPSPL--AFP 1848

 Frog  1242 RSGH-CGLQGKT--LSP----PTIVRQSARNRATD----------APRSPLLKRVQSVEKMAAFL 1289
            ..|| .|....|  .||    ||:  |:|.|..|.          .|.||||:|..|.:::.. .
  Fly  1849 LVGHQPGASNTTQSYSPGSTLPTL--QTAVNANTKKAGFARTKSAEPSSPLLRRALSPDRLHP-R 1910

 Frog  1290 SSGRKASP--------------VDIQHWEDTVDMLEGMSESRTRDWSSEKHERDPEVVVMRRLNL 1340
            |:..|.||              |....|..|    .|.|.|
  Fly  1911 SAETKISPLCCSPPIKQPTHQRVVTTTWRST----PGGSAS------------------------ 1947

 Frog  1341 SERRDSFKKQEAVQEVSFDEPDTGAGEV---APDNKKIGSCSSLWERLPHQTSWIQARTGISTSV 1402
                                   |||..   ||..:.:       :.:|..:...|.:|.::|.|
  Fly  1948 -----------------------GAGGAVLGAPSVQPL-------QLVPAASEESQRQTAMATVV 1982

 Frog  1403 TTQQE------------ASCRLVPQIAVQTSESDEQEKSQGVWECQGFYPL---QLSGKDNCPLV 1452
            :|...            |:|..:|:||.:.......:.|..|.|  ||.|.   ...|:.:....
  Fly  1983 STTAAGTDPSATAVVTLANCEPLPRIAEEKDSPTSTQDSSSVSE--GFMPAIEEFAEGESSSSPT 2045

 Frog  1453 TWLSEPTAASSDRNLPESGKVSECQAPFALSSKRDSKKTS 1492
            ..|.:||...:... ||       ..|...|.|.|..||:
  Fly  2046 QTLEKPTKVKATEQ-PE-------MEPAGKSKKVDQGKTT 2077

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mast3	XP_031761059.1	DUF1908	88..368	CDD:462637	152/364 (42%)
		STKc_MAST	406..685	CDD:270760	209/280 (75%)
		PDZ_MAST3	976..1069	CDD:467288	54/92 (59%)
dop	NP_648778.1	DUF1908	344..702	CDD:462637	152/364 (42%)
		STKc_MAST	834..1115	CDD:270760	209/280 (75%)
		PDZ_MAST	1502..1594	CDD:467189	53/91 (58%)