Protein Alignment XB994119 and ATP8B4

DIOPT Version :9

• Sequence 1: XP_002940236.3
• Gene: XB994119 / 100490503
• XenbaseID: XB-GENE-994120
• Length: 1179
• Species: Xenopus tropicalis
• Sequence 2: XP_011520348.1
• Gene: ATP8B4 / 79895
• HGNCID: 13536
• Length: 1257
• Species: Homo sapiens
• Alignment Length: 1181
• Identity: 760/1181 - (64%)
• Similarity: 936/1181 - (79%)
• Gaps: 30/1181 - (2%)

 Frog     8 CGKKKQPEKERRLRANDRDYNLKFKYATNAIKTCKYNIFTFLPLNLFEQFQRVANAYFVFLLILQ 72
            |.:||..|.||.::||||:||.||:||.|.|.|.||||.||||:||||||||||||||:.|||||
Human    40 CSEKKLREVERIVKANDREYNEKFQYADNRIHTSKYNILTFLPINLFEQFQRVANAYFLCLLILQ 104

 Frog    73 LIPQVSSLSWFTTVVPLVLVLAVSAVKDATDDYYRHKSDNQVNNRTVQVLSNGQFTNEKWMNIQV 137
            |||::|||:||||:||||||:.::|||||||||:|||||||||||..:||.|.:..||||||::|
Human   105 LIPEISSLTWFTTIVPLVLVITMTAVKDATDDYFRHKSDNQVNNRQSEVLINSKLQNEKWMNVKV 169

 Frog   138 GDIIKLENNNFVTADLLLLSSSEPNGLIYIETAELDG---------------------------- 174
            |||||||||.||.|||||||||||:||.|:|||||||
Human   170 GDIIKLENNQFVAADLLLLSSSEPHGLCYVETAELDGSLCCYKDVPWVECQLFGAQEALPTFLKQ 234

 Frog   175 ETNLKVKQSLTVTGDLGEDLEQLSRFDGEVVCEAPNNKLDTFTGTLTYQGEKYSLDNGKILLRGC 239
            ||||||:.:|:||.:||.|:.:|:.|||.||||.||||||.|.|.|:::..|:||:|.||:||||
Human   235 ETNLKVRHALSVTSELGADISRLAGFDGIVVCEVPNNKLDKFMGILSWKDSKHSLNNEKIILRGC 299

 Frog   240 TLRNTDWCFGMVIFAGPDTKLMQNSGKSTLKRTSIDRLMNILVLWIFVFLAAMCIILAIGNGIWE 304
            .||||.|||||||||||||||||||||:..||||||||||.||||||.||..:.|||||||.|||
Human   300 ILRNTSWCFGMVIFAGPDTKLMQNSGKTKFKRTSIDRLMNTLVLWIFGFLICLGIILAIGNSIWE 364

 Frog   305 SNQGYYFQVYLPWAEGVTNAAFSGFLMFWSYVIILNTVVPISLYVSVEIIRLGNSYYINWDRKMY 369
            |..|..|:.:|.|.||..::.|||||.||||:||||||||||||||||:||||:||:||||||||
Human   365 SQTGDQFRTFLFWNEGEKSSVFSGFLTFWSYIIILNTVVPISLYVSVEVIRLGHSYFINWDRKMY 429

 Frog   370 YPKKDTPAEARTTTLNEELGQIKYIFSDKTGTLTQNIMTFNKCSINGNSYGDVYDYAGNRLEINE 434
            |.:|..||.|||||||||||||:|||||||||||||||||.:|||||..||:|:|....:.||.:
Human   430 YSRKAIPAVARTTTLNEELGQIEYIFSDKTGTLTQNIMTFKRCSINGRIYGEVHDDLDQKTEITQ 494

 Frog   435 HTEKVDFSFNPLADPKFSFHDHRLVESVKLGEPATHEFFRLLALCHTAMSEEKKPGELVYQAQSP 499
            ..|.||||....||.:|.|.||.|:||:|:|:|..|||.||||||||.||||...|||:||.|||
Human   495 EKEPVDFSVKSQADREFQFFDHHLMESIKMGDPKVHEFLRLLALCHTVMSEENSAGELIYQVQSP 559

 Frog   500 DEGALVTAARNFGFVFRTRTPETITVVEMGETKVYELQAILDFNNERKRMSVIVKSPDGRLILYC 564
            ||||||||||||||:|::|||||||:.|:|....|:|.|.|||||.||||||||::|:|::.||.
Human   560 DEGALVTAARNFGFIFKSRTPETITIEELGTLVTYQLLAFLDFNNTRKRMSVIVRNPEGQIKLYS 624

 Frog   565 KGADTIVYELLDQSSEDLKETTTEHLNEFAGEGLRTLVLACKELNPTYFRDWKQRHHEASTSLDD 629
            ||||||::|.|..|:|.|...|::||:||||||||||.:|.::|:..||::|.:...:|:.:.::
Human   625 KGADTILFEKLHPSNEVLLSLTSDHLSEFAGEGLRTLAIAYRDLDDKYFKEWHKMLEDANAATEE 689

 Frog   630 REEKLAKLYEEIEKDLKLLGASAIEDKLQDGVPQTIETLSKANIKIWVLTGDKQETAENIGYSCN 694
            |:|::|.||||||:||.||||:|:|||||:||.:|:.:||.||||||||||||||||.||||:||
Human   690 RDERIAGLYEEIERDLMLLGATAVEDKLQEGVIETVTSLSLANIKIWVLTGDKQETAINIGYACN 754

 Frog   695 MLQDEMKEVFIIKGCSPDEVLEELRSARRKMNPESFSETNEVNVYLQKKSKKSQIIPDDELKGSD 759
            ||.|:|.:||:|.|.:..||.||||.|::.:..::.:.:|...|..:|:..:...|.::.:.|.
Human   755 MLTDDMNDVFVIAGNNAVEVREELRKAKQNLFGQNRNFSNGHVVCEKKQQLELDSIVEETITGD- 818

 Frog   760 TFGILINGHSLAFALEESMEIELLRTACMCTAVICCRVTPLQKAQVVQLVKKYKKAVTLAIGDGA 824
             :.::|||||||.|||..::.:||..||||..|||||||||||||||:|||||:.||||||||||
Human   819 -YALIINGHSLAHALESDVKNDLLELACMCKTVICCRVTPLQKAQVVELVKKYRNAVTLAIGDGA 882

 Frog   825 NDVSMIKTAHIGVGISGQEGMQAVLSSDFSFAQFRYLQRLLLVHGRWSYIRMCRFLRYFFYKNFT 889
            |||||||:||||||||||||:||||:||:||||||||||||||||||||.|||:||.|||||||.
Human   883 NDVSMIKSAHIGVGISGQEGLQAVLASDYSFAQFRYLQRLLLVHGRWSYFRMCKFLCYFFYKNFA 947

 Frog   890 FTLVHFWYGFFCGFSAQTVYDEWFITLYNLVYTSLPVLGMSLFDQDVNDRWSLQFPELYEPGQMN 954
            |||||||:|||||||||||||:|||||:|:||||||||.|.:|||||:|:.|:..|:||:|||:|
Human   948 FTLVHFWFGFFCGFSAQTVYDQWFITLFNIVYTSLPVLAMGIFDQDVSDQNSVDCPQLYKPGQLN 1012

 Frog   955 RYFNIKEFIKCVLHGIYSSLILFFIPFGAMYESVREDGRAISDYQSFALMAQTCLLLVVSVQIGL 1019
            ..||.::|..|||||||:||:|||||:||.|....|||:.|:||||||:...|.|::||||||.|
Human  1013 LLFNKRKFFICVLHGIYTSLVLFFIPYGAFYNVAGEDGQHIADYQSFAVTMATSLVIVVSVQIAL 1077

 Frog  1020 DTAYWTAVNQFFIWGSMAVYFAITFTMYSDGMYLIFTGSFPFIGTARNTLNQPGVWLAIFLTTVL 1084
            ||:|||.:|..|||||:|:||:|.|||:|:|::.||...|||:|.||::|.|..:||.|.||||.
Human  1078 DTSYWTFINHVFIWGSIAIYFSILFTMHSNGIFGIFPNQFPFVGNARHSLTQKCIWLVILLTTVA 1142

 Frog  1085 CVLPVVAFRFLRSELFPSTGDKIQKKIREAKKRPPPPPPKARLRRTSSRRSGYAFSHQQGYGDLI 1149
            .|:||||||||:.:|:|:..|:|::..:..||..||...:.|.||:|||||||||:||:|||:||
Human  1143 SVMPVVAFRFLKVDLYPTLSDQIRRWQKAQKKARPPSSRRPRTRRSSSRRSGYAFAHQEGYGELI 1207

 Frog  1150 TSGRNFRPKIP 1160
            |||:|.|.|.|
Human  1208 TSGKNMRAKNP 1218

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
XB994119	XP_002940236.3	P-type_ATPase_APLT_Dnf-like	36..980	CDD:319770	640/971 (66%)
ATP8B4	XP_011520348.1	PhoLip_ATPase_N	51..116	CDD:292826	47/64 (73%)
		ATPase-Plipid	65..1167	CDD:273734	716/1103 (65%)
		Cation_ATPase	538..634	CDD:289987	66/95 (69%)
		HAD_like	<875..906	CDD:304363	28/30 (93%)
		PhoLip_ATPase_C	906..1160	CDD:292829	171/253 (68%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
NCBI	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D23350at32523
OrthoFinder	1	1.000	-	-		FOG0000076
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X168
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.010