Protein Alignment XB994119 and ATP8B2

DIOPT Version :9

• Sequence 1: XP_002940236.3
• Gene: XB994119 / 100490503
• XenbaseID: XB-GENE-994120
• Length: 1179
• Species: Xenopus tropicalis
• Sequence 2: NP_001354863.1
• Gene: ATP8B2 / 57198
• HGNCID: 13534
• Length: 1209
• Species: Homo sapiens
• Alignment Length: 1152
• Identity: 783/1152 - (67%)
• Similarity: 939/1152 - (81%)
• Gaps: 12/1152 - (1%)

 Frog    11 KKQP----EKERRLRANDRDYNLKFKYATNAIKTCKYNIFTFLPLNLFEQFQRVANAYFVFLLIL 71
            :|:|    |:|||.|||||:||.||:||:|.|||.||||.||||:|||||||.|||.||:|||||
Human    22 RKKPSWGTEEERRARANDREYNEKFQYASNCIKTSKYNILTFLPVNLFEQFQEVANTYFLFLLIL 86

 Frog    72 QLIPQVSSLSWFTTVVPLVLVLAVSAVKDATDDYYRHKSDNQVNNRTVQVLSNGQFTNEKWMNIQ 136
            |||||:||||||||:|||||||.::|||||||||:|||||||||||..|||.||....|:|||:.
Human    87 QLIPQISSLSWFTTIVPLVLVLTITAVKDATDDYFRHKSDNQVNNRQSQVLINGILQQEQWMNVC 151

 Frog   137 VGDIIKLENNNFVTADLLLLSSSEPNGLIYIETAELDGETNLKVKQSLTVTGDLGEDLEQLSRFD 201
            ||||||||||.||.|||||||||||:||.||||||||||||:||:|::.||.:|| |:.:|::||
Human   152 VGDIIKLENNQFVAADLLLLSSSEPHGLCYIETAELDGETNMKVRQAIPVTSELG-DISKLAKFD 215

 Frog   202 GEVVCEAPNNKLDTFTGTLTYQGEKYSLDNGKILLRGCTLRNTDWCFGMVIFAGPDTKLMQNSGK 266
            |||:||.||||||.|:|||.::..|:.|.|..:|||||.||||:||||:|||||||||||||||:
Human   216 GEVICEPPNNKLDKFSGTLYWKENKFPLSNQNMLLRGCVLRNTEWCFGLVIFAGPDTKLMQNSGR 280

 Frog   267 STLKRTSIDRLMNILVLWIFVFLAAMCIILAIGNGIWESNQGYYFQVYLPWAEGVTNAAFSGFLM 331
            :..||||||||||.||||||.||..|.:||||||.|||...|..|||||||.|.|.:|.|||||.
Human   281 TKFKRTSIDRLMNTLVLWIFGFLVCMGVILAIGNAIWEHEVGMRFQVYLPWDEAVDSAFFSGFLS 345

 Frog   332 FWSYVIILNTVVPISLYVSVEIIRLGNSYYINWDRKMYYPKKDTPAEARTTTLNEELGQIKYIFS 396
            ||||:||||||||||||||||:||||:||:||||:||:..||.||||||||||||||||::||||
Human   346 FWSYIIILNTVVPISLYVSVEVIRLGHSYFINWDKKMFCMKKRTPAEARTTTLNEELGQVEYIFS 410

 Frog   397 DKTGTLTQNIMTFNKCSINGNSYGDVYDYAGNRLEINEHTEKVDFSFNPLADPKFSFHDHRLVES 461
            |||||||||||.||||||||:|||||:|..|::.|:.|..|.||||||||||.||.|.|..|:|:
Human   411 DKTGTLTQNIMVFNKCSINGHSYGDVFDVLGHKAELGERPEPVDFSFNPLADKKFLFWDPSLLEA 475

 Frog   462 VKLGEPATHEFFRLLALCHTAMSEEKKPGELVYQAQSPDEGALVTAARNFGFVFRTRTPETITVV 526
            ||:|:|.||||||||:||||.|||||..|||.|:|||||||||||||||||||||:|||:||||.
Human   476 VKIGDPHTHEFFRLLSLCHTVMSEEKNEGELYYKAQSPDEGALVTAARNFGFVFRSRTPKTITVH 540

 Frog   527 EMGETKVYELQAILDFNNERKRMSVIVKSPDGRLILYCKGADTIVYELLDQSSEDLKETTTEHLN 591
            |||....|:|.|||||||.||||||||::|:|::.|||||||||:.:.|..|:::|..||.:|||
Human   541 EMGTAITYQLLAILDFNNIRKRMSVIVRNPEGKIRLYCKGADTILLDRLHHSTQELLNTTMDHLN 605

 Frog   592 EFAGEGLRTLVLACKELNPTYFRDWKQRHHEASTSLDDREEKLAKLYEEIEKDLKLLGASAIEDK 656
            |:|||||||||||.|:|:..|:.:|.:|..:||.:.|.||::||.:|||:|.::.||||:|||||
Human   606 EYAGEGLRTLVLAYKDLDEEYYEEWAERRLQASLAQDSREDRLASIYEEVENNMMLLGATAIEDK 670

 Frog   657 LQDGVPQTIETLSKANIKIWVLTGDKQETAENIGYSCNMLQDEMKEVFIIKGCSPDEVLEELRSA 721
            ||.|||:||..|:.||||||||||||||||.||||||.||.|:|.||||:.|.:..||.||||.|
Human   671 LQQGVPETIALLTLANIKIWVLTGDKQETAVNIGYSCKMLTDDMTEVFIVTGHTVLEVREELRKA 735

 Frog   722 RRKMNPESFSETNEVNVYLQK--KSKKSQIIPDDELKGSDTFGILINGHSLAFALEESMEIELLR 784
            |.||...|.|..|.. .|..|  .||.:.::  :.:.|.  :.::|||||||.|||..||:|.|.
Human   736 REKMMDSSRSVGNGF-TYQDKLSSSKLTSVL--EAVAGE--YALVINGHSLAHALEADMELEFLE 795

 Frog   785 TACMCTAVICCRVTPLQKAQVVQLVKKYKKAVTLAIGDGANDVSMIKTAHIGVGISGQEGMQAVL 849
            |||.|.||||||||||||||||:|||||||||||||||||||||||||||||||||||||:||||
Human   796 TACACKAVICCRVTPLQKAQVVELVKKYKKAVTLAIGDGANDVSMIKTAHIGVGISGQEGIQAVL 860

 Frog   850 SSDFSFAQFRYLQRLLLVHGRWSYIRMCRFLRYFFYKNFTFTLVHFWYGFFCGFSAQTVYDEWFI 914
            :||:||:||::|||||||||||||:|||:||.|||||||.||:||||:|||||||||||||::||
Human   861 ASDYSFSQFKFLQRLLLVHGRWSYLRMCKFLCYFFYKNFAFTMVHFWFGFFCGFSAQTVYDQYFI 925

 Frog   915 TLYNLVYTSLPVLGMSLFDQDVNDRWSLQFPELYEPGQMNRYFNIKEFIKCVLHGIYSSLILFFI 979
            ||||:||||||||.|.:|||||.::.|:::|:||||||:|..||.:||..|:..|||:|:::|||
Human   926 TLYNIVYTSLPVLAMGVFDQDVPEQRSMEYPKLYEPGQLNLLFNKREFFICIAQGIYTSVLMFFI 990

 Frog   980 PFGAMYESVREDGRAISDYQSFALMAQTCLLLVVSVQIGLDTAYWTAVNQFFIWGSMAVYFAITF 1044
            |:|...::.|:||..::||||||:...|.|::||||||||||.||||:|.||||||:||||||.|
Human   991 PYGVFADATRDDGTQLADYQSFAVTVATSLVIVVSVQIGLDTGYWTAINHFFIWGSLAVYFAILF 1055

 Frog  1045 TMYSDGMYLIFTGSFPFIGTARNTLNQPGVWLAIFLTTVLCVLPVVAFRFLRSELFPSTGDKIQK 1109
            .|:|:|::.:|...|.|:|.|:|||.||.|||.|.||||:|::|||||||||..|.|...|.::.
Human  1056 AMHSNGLFDMFPNQFRFVGNAQNTLAQPTVWLTIVLTTVVCIMPVVAFRFLRLNLKPDLSDTVRY 1120

 Frog  1110 KIREAKKRPPPPPPKARLRRTSSRRSGYAFSHQQGYGDLITSGRNFR 1156
            .....||:........|:.||.|||||||||||:|:|:||.||:|.|
Human  1121 TQLVRKKQKAQHRCMRRVGRTGSRRSGYAFSHQEGFGELIMSGKNMR 1167

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
XB994119	XP_002940236.3	P-type_ATPase_APLT_Dnf-like	36..980	CDD:319770	666/945 (70%)
ATP8B2	NP_001354863.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..36		6/13 (46%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1181..1209

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
NCBI	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D23350at32523
OrthoFinder	1	1.000	-	-		FOG0000076
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X168
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.010