Protein Alignment XB994119 and ATP8B1

DIOPT Version :9

• Sequence 1: XP_002940236.3
• Gene: XB994119 / 100490503
• XenbaseID: XB-GENE-994120
• Length: 1179
• Species: Xenopus tropicalis
• Sequence 2: NP_001361314.1
• Gene: ATP8B1 / 5205
• HGNCID: 3706
• Length: 1251
• Species: Homo sapiens
• Alignment Length: 1214
• Identity: 663/1214 - (54%)
• Similarity: 844/1214 - (69%)
• Gaps: 84/1214 - (6%)

 Frog     9 GKKKQPEKER------------------RLRANDRDY-------NLKF------KYATNAIKTCK 42
            |...:||:.|                  :::||||.|       |.||      |||.|||||.|
Human    37 GSAVEPEQNRVNREAEENREPFRKECTWQVKANDRKYHEQPHFMNTKFLCIKESKYANNAIKTYK 101

 Frog    43 YNIFTFLPLNLFEQFQRVANAYFVFLLILQLIPQVSSLSWFTTVVPLVLVLAVSAVKDATDDYYR 107
            ||.|||:|:||||||:|.||.||:.|||||.:||:|:|:|:||:|||::||.|:|:||..||..|
Human   102 YNAFTFIPMNLFEQFKRAANLYFLALLILQAVPQISTLAWYTTLVPLLVVLGVTAIKDLVDDVAR 166

 Frog   108 HKSDNQVNNRTVQVLSNGQFTNEKWMNIQVGDIIKLENNNFVTADLLLLSSSEPNGLIYIETAEL 172
            ||.|.::||||.:|:.:|:|...||..|||||:|:|:.|:||.||:|||||||||.|.|:|||||
Human   167 HKMDKEINNRTCEVIKDGRFKVAKWKEIQVGDVIRLKKNDFVPADILLLSSSEPNSLCYVETAEL 231

 Frog   173 DGETNLKVKQSLTVTGDLGEDLEQLSRFDGEVVCEAPNNKLDTFTGTLTYQGEKYSLDNGKILLR 237
            |||||||.|.||.:|....:..:.|:.|||.:.||.|||:||.|||||.::...:.||..|||||
Human   232 DGETNLKFKMSLEITDQYLQREDTLATFDGFIECEEPNNRLDKFTGTLFWRNTSFPLDADKILLR 296

 Frog   238 GCTLRNTDWCFGMVIFAGPDTKLMQNSGKSTLKRTSIDRLMNILVLWIFVFLAAMCIILAIGNGI 302
            ||.:||||:|.|:|||||.|||:|:||||:..|||.||.|||.:|..|||.|..:...||||:..
Human   297 GCVIRNTDFCHGLVIFAGADTKIMKNSGKTRFKRTKIDYLMNYMVYTIFVVLILLSAGLAIGHAY 361

 Frog   303 WES---NQGYYFQVYLPWAEGVTNA-AFSGFLMFWSYVIILNTVVPISLYVSVEIIRLGNSYYIN 363
            ||:   |..:|..      :|..:. ::.|||:||.|:|:|||:||||||||||:||||.|::||
Human   362 WEAQVGNSSWYLY------DGEDDTPSYRGFLIFWGYIIVLNTMVPISLYVSVEVIRLGQSHFIN 420

 Frog   364 WDRKMYYPKKDTPAEARTTTLNEELGQIKYIFSDKTGTLTQNIMTFNKCSINGNSYGDVYDYAGN 428
            ||.:|||.:|||||:||||||||:||||.|||||||||||||||||.||.|||..|||..|.:.:
Human   421 WDLQMYYAEKDTPAKARTTTLNEQLGQIHYIFSDKTGTLTQNIMTFKKCCINGQIYGDHRDASQH 485

 Frog   429 RLEINEHTEKVDFSFNPLADPKFSFHDHRLVESVKLG-EPATHEFFRLLALCHTAMSEEKKPGEL 492
            .   :...|:||||:|..||.|.:|:||.|:|.::.| ||...:||.|||:|||.| .::..|:|
Human   486 N---HNKIEQVDFSWNTYADGKLAFYDHYLIEQIQSGKEPEVRQFFFLLAVCHTVM-VDRTDGQL 546

 Frog   493 VYQAQSPDEGALVTAARNFGFVFRTRTPETITVVEMGETKVYELQAILDFNNERKRMSVIVKSPD 557
            .|||.||||||||.|||||||.|..||..|||:.|:|..:.|.:.||||||::|||||:||::|:
Human   547 NYQAASPDEGALVNAARNFGFAFLARTQNTITISELGTERTYNVLAILDFNSDRKRMSIIVRTPE 611

 Frog   558 GRLILYCKGADTIVYELLDQSSEDLKETTTEHLNEFAGEGLRTLVLACKELNPTYFRDWKQRHHE 622
            |.:.||||||||::||.|.:.: ..|:.|.:.|:.||.|.||||.|..||:....|.:|.::...
Human   612 GNIKLYCKGADTVIYERLHRMN-PTKQETQDALDIFANETLRTLCLCYKEIEEKEFTEWNKKFMA 675

 Frog   623 ASTSLDDREEKLAKLYEEIEKDLKLLGASAIEDKLQDGVPQTIETLSKANIKIWVLTGDKQETAE 687
            ||.:..:|:|.|.|:||||||||.||||:|||||||||||:||..|:||:||||||||||:||||
Human   676 ASVASTNRDEALDKVYEEIEKDLILLGATAIEDKLQDGVPETISKLAKADIKIWVLTGDKKETAE 740

 Frog   688 NIGYSCNMLQDEMKEVFIIKGCSPDEVLEELRSAR-----------RKMNP---ESF-------- 730
            |||::|.:|.::....:       .|.:..|..||           .|..|   |||
Human   741 NIGFACELLTEDTTICY-------GEDINSLLHARMENQRNRGGVYAKFAPPVQESFFPPGGNRA 798

 Frog   731 -----SETNEVNVYLQKKSKKSQIIPDDELKGSDTFGILINGHSLAFALEESMEIELLRTACMCT 790
                 |..||  :.|:||:|:::|:.....:..:...:.........|.:|..:...:..||.|:
Human   799 LIITGSWLNE--ILLEKKTKRNKILKLKFPRTEEERRMRTQSKRRLEAKKEQRQKNFVDLACECS 861

 Frog   791 AVICCRVTPLQKAQVVQLVKKYKKAVTLAIGDGANDVSMIKTAHIGVGISGQEGMQAVLSSDFSF 855
            |||||||||.|||.||.|||:||||:|||||||||||:||||||||||||||||||||:|||:||
Human   862 AVICCRVTPKQKAMVVDLVKRYKKAITLAIGDGANDVNMIKTAHIGVGISGQEGMQAVMSSDYSF 926

 Frog   856 AQFRYLQRLLLVHGRWSYIRMCRFLRYFFYKNFTFTLVHFWYGFFCGFSAQTVYDEWFITLYNLV 920
            ||||||||||||||||||||||:||||||||||.||||||||.||.|:||||.|::|||||||::
Human   927 AQFRYLQRLLLVHGRWSYIRMCKFLRYFFYKNFAFTLVHFWYSFFNGYSAQTAYEDWFITLYNVL 991

 Frog   921 YTSLPVLGMSLFDQDVNDRWSLQFPELYEPGQMNRYFNIKEFIKCVLHGIYSSLILFFIPFGAMY 985
            |||||||.|.|.||||:|:.||:||.||..||.:..||.|.|...:|||:.:|:||||||.||..
Human   992 YTSLPVLLMGLLDQDVSDKLSLRFPGLYIVGQRDLLFNYKRFFVSLLHGVLTSMILFFIPLGAYL 1056

 Frog   986 ESVREDGRAISDYQSFALMAQTCLLLVVSVQIGLDTAYWTAVNQFFIWGSMAVYFAITFTMYSDG 1050
            ::|.:||.|.|||||||:...:.|::.|:.||||||:|||.||.|.|:||:|:||.|.|..:|.|
Human  1057 QTVGQDGEAPSDYQSFAVTIASALVITVNFQIGLDTSYWTFVNAFSIFGSIALYFGIMFDFHSAG 1121

 Frog  1051 MYLIFTGSFPFIGTARNTLNQPGVWLAIFLTTVLCVLPVVAFRFLRSELFPSTGDKIQKKIREAK 1115
            ::::|..:|.|.|||.|.|.||.:||.|.|...:|:|||||.|||...::||..|||||..:..|
Human  1122 IHVLFPSAFQFTGTASNALRQPYIWLTIILAVAVCLLPVVAIRFLSMTIWPSESDKIQKHRKRLK 1186

 Frog  1116 KRPPPPPPKARLRR-TSSRRSGYAFSHQQGYGDLITSGRNFRPK 1158
            ........:...|| .|:|||.||||||:||.|||:|||:.|.|
Human  1187 AEEQWQRRQQVFRRGVSTRRSAYAFSHQRGYADLISSGRSIRKK 1230

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
XB994119	XP_002940236.3	P-type_ATPase_APLT_Dnf-like	36..980	CDD:319770	556/975 (57%)
ATP8B1	NP_001361314.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..54		4/16 (25%)
		P-type_ATPase_APLT_Dnf-like	94..1051	CDD:319770	556/976 (57%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
NCBI	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D39163at33208
OrthoFinder	1	1.000	-	-		FOG0000076
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X168
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.010