Protein Alignment XB994119 and ATP8A2

DIOPT Version :9

• Sequence 1: XP_002940236.3
• Gene: XB994119 / 100490503
• XenbaseID: XB-GENE-994120
• Length: 1179
• Species: Xenopus tropicalis
• Sequence 2: NP_057613.4
• Gene: ATP8A2 / 51761
• HGNCID: 13533
• Length: 1188
• Species: Homo sapiens
• Alignment Length: 1185
• Identity: 479/1185 - (40%)
• Similarity: 700/1185 - (59%)
• Gaps: 105/1185 - (8%)

 Frog    10 KKKQPEKER------RLRANDRDYNLK----FKYATNAIKTCKYNIFTFLPLNLFEQFQRVANAY 64
            ||.:.|..|      :|.|..|...|.    .|:..|.|.|.||::.||||..|:||.:|.|||:
Human    35 KKAEDEMSRATSVGDQLEAPARTIYLNQPHLNKFRDNQISTAKYSVLTFLPRFLYEQIRRAANAF 99

 Frog    65 FVFLLILQLIPQVSSLSWFTTVVPLVLVLAVSAVKDATDDYYRHKSDNQVNNRTVQVLSNGQFTN 129
            |:|:.:||.||.||....:||:|||:::|.::.:|:..:|:.|||:||.||.:...||.||.:..
Human   100 FLFIALLQQIPDVSPTGRYTTLVPLIIILTIAGIKEIVEDFKRHKADNAVNKKKTIVLRNGMWHT 164

 Frog   130 EKWMNIQVGDIIKLENNNFVTADLLLLSSSEPNGLIYIETAELDGETNLKVKQSLTVTGDLGEDL 194
            ..|..:.||||:|:.|..::.||::|||||||..:.|:|||.||||||||::|.|:.|.|: :..
Human   165 IMWKEVAVGDIVKVVNGQYLPADVVLLSSSEPQAMCYVETANLDGETNLKIRQGLSHTADM-QTR 228

 Frog   195 EQLSRFDGEVVCEAPNNKLDTFTGTLTYQGEK-YSLDNGKILLRGCTLRNTDWCFGMVIFAGPDT 258
            |.|.:..|.:.||.||..|..|||.|...|:. .:|...:|||||..||||.|.||:|::.|.||
Human   229 EVLMKLSGTIECEGPNRHLYDFTGNLNLDGKSLVALGPDQILLRGTQLRNTQWVFGIVVYTGHDT 293

 Frog   259 KLMQNSGKSTLKRTSIDRLMNILVLWIFVFLAAMCIILAIGNGIWESNQG---YYFQVYLPWAEG 320
            ||||||.|:.|||::::::.|:.:|.:|..|..|.::.:.|...|..:.|   :|.:     ...
Human   294 KLMQNSTKAPLKRSNVEKVTNVQILVLFGILLVMALVSSAGALYWNRSHGEKNWYIK-----KMD 353

 Frog   321 VTNAAFSGFLMFWSYVIILNTVVPISLYVSVEIIRLGNSYYINWDRKMYYPKKDTPAEARTTTLN 385
            .|:..|...|:  :::|:.|.::||||.|::|:::...:.:||||..|||...||||.|||:.||
Human   354 TTSDNFGYNLL--TFIILYNNLIPISLLVTLEVVKYTQALFINWDTDMYYIGNDTPAMARTSNLN 416

 Frog   386 EELGQIKYIFSDKTGTLTQNIMTFNKCSINGNSYGDVYDYAGNRLEINEHTEKVDF-SFNPLADP 449
            |||||:||:|||||||||.|||.|.||||.|.:|       |:..|:.......|| ...|....
Human   417 EELGQVKYLFSDKTGTLTCNIMNFKKCSIAGVTY-------GHFPELAREPSSDDFCRMPPPCSD 474

 Frog   450 KFSFHDHRLVESVKLGEPAT---HEFFRLLALCHTAMSEEKKPGE-LVYQAQSPDEGALVTAARN 510
            ...|.|.||:::::...|..   .||..|||:|||.:.|  |.|: ::|||.||||.|||..|:.
Human   475 SCDFDDPRLLKNIEDRHPTAPCIQEFLTLLAVCHTVVPE--KDGDNIIYQASSPDEAALVKGAKK 537

 Frog   511 FGFVFRTRTPETITVVEMGETKVYELQAILDFNNERKRMSVIVKSPDGRLILYCKGADTIVYELL 575
            .||||..|||.::.:..||:.:.:.:..:|:|:::||||||||::|.|||.|||||||.:::|.|
Human   538 LGFVFTARTPFSVIIEAMGQEQTFGILNVLEFSSDRKRMSVIVRTPSGRLRLYCKGADNVIFERL 602

 Frog   576 DQSSEDLKETTTEHLNEFAGEGLRTLVLACKELNPTYFRDWKQRHHEASTSLDDREEKLAKLYEE 640
            .:.|:.::||.. ||..||.||||||.:|..:|:...:.:|.:.:.||||.|.||.::|.:.||.
Human   603 SKDSKYMEETLC-HLEYFATEGLRTLCVAYADLSENEYEEWLKVYQEASTILKDRAQRLEECYEI 666

 Frog   641 IEKDLKLLGASAIEDKLQDGVPQTIETLSKANIKIWVLTGDKQETAENIGYSCNMLQDEMKEVFI 705
            |||:|.||||:||||:||.|||:||.||.||.||||||||||||||.||||||.::...|..:.:
Human   667 IEKNLLLLGATAIEDRLQAGVPETIATLLKAEIKIWVLTGDKQETAINIGYSCRLVSQNMALILL 731

 Frog   706 IKGCSPDEVLEELRSARRKMNPESFSETNEVNVYLQKKSKKSQIIPDDELKGSDTFGILINGHSL 770
                 .::.|:..|:|..:       ...::...|.|:               :...::|:||:|
Human   732 -----KEDSLDATRAAITQ-------HCTDLGNLLGKE---------------NDVALIIDGHTL 769

 Frog   771 AFALEESMEIELLRTACMCTAVICCRVTPLQKAQVVQLVKKYKKAVTLAIGDGANDVSMIKTAHI 835
            .:||...:....|..|..|.|||||||:||||:::|.:|||..||:|||||||||||.||:|||:
Human   770 KYALSFEVRRSFLDLALSCKAVICCRVSPLQKSEIVDVVKKRVKAITLAIGDGANDVGMIQTAHV 834

 Frog   836 GVGISGQEGMQAVLSSDFSFAQFRYLQRLLLVHGRWSYIRMCRFLRYFFYKNFTFTLVHFWYGFF 900
            ||||||.|||||..:||::.|||.||::||||||.|||.|:.:.:.|.||||....::..|:.|.
Human   835 GVGISGNEGMQATNNSDYAIAQFSYLEKLLLVHGAWSYNRVTKCILYCFYKNVVLYIIELWFAFV 899

 Frog   901 CGFSAQTVYDEWFITLYNLVYTSLPVLGMSLFDQDVNDRWSLQFPELYEPGQMNRYFNIKEFIKC 965
            .|||.|.:::.|.|.|||:::|:||...:.:|::.......|:||:||:..|....||.|.|...
Human   900 NGFSGQILFERWCIGLYNVIFTALPPFTLGIFERSCTQESMLRFPQLYKITQNGEGFNTKVFWGH 964

 Frog   966 VLHGIYSSLILFFIPFGAM-YESVREDGRAISDYQSFALMAQTCLLLVVSVQIGLDTAYWTAVNQ 1029
            .::.:..|||||:.|..|: :::|...|.| :||.....:..|.:::.|.::.||:|..||..:.
Human   965 CINALVHSLILFWFPMKALEHDTVLTSGHA-TDYLFVGNIVYTYVVVTVCLKAGLETTAWTKFSH 1028

 Frog  1030 FFIWGSMAVYFAITFTMYSDGMYLIFTGSFPFI----GTARNTLNQPGVWLAIFLTTVLCVLPVV 1090
            ..:||||     :|:.::. |:|.....:.|..    |.|...|:....||.:||....|::..|
Human  1029 LAVWGSM-----LTWLVFF-GIYSTIWPTIPIAPDMRGQATMVLSSAHFWLGLFLVPTACLIEDV 1087

 Frog  1091 AFRFL-----------------------RSELFPSTGDKIQKKIREAKKRPPPPPPKARLRRTSS 1132
            |:|..                       ::.|..|.|.::.::.|..|:.....||  .|.|.||
Human  1088 AWRAAKHTCKKTLLEEVQELETKSRVLGKAVLRDSNGKRLNERDRLIKRLGRKTPP--TLFRGSS 1150

 Frog  1133 RRS----GYAFSHQQ 1143
            .:.    |||||.::
Human  1151 LQQGVPHGYAFSQEE 1165

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
XB994119	XP_002940236.3	P-type_ATPase_APLT_Dnf-like	36..980	CDD:319770	421/952 (44%)
ATP8A2	NP_057613.4	ATPase-Plipid	68..1106	CDD:273734	454/1089 (42%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1162..1188		1/4 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
NCBI	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D587717at2759
OrthoFinder	1	1.000	-	-		FOG0000076
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X168
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.010