DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment stx7 and Syx7

DIOPT Version :9

Sequence 1:	XP_002936355.1	Gene:	stx7 / 100379927	XenbaseID:	XB-GENE-1004004	Length:	259	Species:	Xenopus tropicalis
Sequence 2:	NP_730632.1	Gene:	Syx7 / 36173	FlyBaseID:	FBgn0267849	Length:	282	Species:	Drosophila melanogaster

Alignment Length:	268	Identity:	95/268 - (35%)
Similarity:	146/268 - (54%)	Gaps:	35/268 - (13%)

- Green bases have known domain annotations that are detailed below.

Frog     8 DPAQLAQTISGNIQKITQSSSEIQRIVNQLGTVQDTAELRNRLQEKIQYAHKIAKDT-------D 65
            |..:|||.|:.:|||:.|:.|.:||:||||.|.||:.||:.:|.:.:.|.:::..||       |
  Fly    22 DFQRLAQIIATSIQKVQQNVSTMQRMVNQLNTPQDSPELKKQLHQIMTYTNQLVTDTNNQINEVD 86

Frog    66 RCLKDYASLPLESDQRQRKLQKDRLVSEFSSVLNNFQKIQRQAAEKEKEF----------VARVR 120
            :|           .:|..|:|:||||.||::.|..||.:||:.|:.||..          :||..
  Fly    87 KC-----------KERHLKIQRDRLVDEFTAALTAFQSVQRKTADIEKTALRQARGDSYNIARPP 140

Frog   121 AGSRVSGGFPDDSQKEGSLLTWEN-----EGQPQATMQEEEITEDDLHLIEERETAIRQLEEDIQ 180
            ..||........||::.:....:|     ..|.|...|.||  :.||..:||:|..||:||.:|.
  Fly   141 GSSRTGSSNSSASQQDNNSFFEDNFFNRKSNQQQMQTQMEE--QADLQALEEQEQVIRELENNIV 203

Frog   181 GINDIFKDLGMMVHEQGEMIDSIEANVENADVHVQQANQQLARAAEYQRKSRRKICIIIAVLVVA 245
            |:|:|:|.||.:|:|||..:||||:.||...:.|.|..:.|.:|:.|:.|.|:|..|::.:|...
  Fly   204 GVNEIYKKLGALVYEQGLTVDSIESQVEQTSIFVSQGTENLRKASSYRNKVRKKKLILVGILSAV 268

Frog   246 ATVIGLII 253
            ...|.||:
  Fly   269 LLAIILIL 276

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
stx7	XP_002936355.1	Syntaxin_2	16..116	CDD:373109	40/116 (34%)
stx7	XP_002936355.1	SNARE_syntaxin7	165..224	CDD:277228	27/58 (47%)
Syx7	NP_730632.1	Syntaxin_2	30..126	CDD:291208	40/106 (38%)
		COG5325	<97..276	CDD:227635	64/180 (36%)
		SNARE	188..247	CDD:304603	27/58 (47%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	75	1.000	Domainoid score	I8900
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H37823
Inparanoid	1	1.050	155	1.000	Inparanoid score	I4205
OMA	1	1.010	-	-		QHG53539
OrthoDB	1	1.010	-	-		D1204812at2759
OrthoFinder	1	1.000	-	-		FOG0000747
OrthoInspector	1	1.000	-	-		otm47591
Panther	1	1.100	-	-	O	PTHR19957
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3589
SonicParanoid	1	1.000	-	-		X633
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	12	12.110