Protein Alignment Ap1g2 and AP-2alpha

DIOPT Version :9

• Sequence 1: XP_002728326.1
• Gene: Ap1g2 / 100362547
• RGDID: 2324507
• Length: 785
• Species: Rattus norvegicus
• Sequence 2: NP_995607.1
• Gene: AP-2alpha / 33211
• FlyBaseID: FBgn0264855
• Length: 952
• Species: Drosophila melanogaster
• Alignment Length: 665
• Identity: 189/665 - (28%)
• Similarity: 323/665 - (48%)
• Gaps: 88/665 - (13%)

  Rat    11 IEEIRGAK-------------TQAQEREV--IQKECAQIRASFRDG---DPLQRHRQLAKLLYVH 57
            |::.||.|             .:::|.||  |.||.|.||:.|:..   |..|:.:.:.|||::.
  Fly    13 IDQSRGGKESEASADESLLFYCKSKEAEVKRINKELANIRSKFKGDKTLDGYQKKKYVCKLLFIF 77

  Rat    58 MLGYPAHFGQMECLKLIASPRFTDKRVGYLGAMLLLDERHDAHLLITNSIKNDLSQGIQPVQ-GL 121
            :||:...||.||.:.|::|.::::|::|||...:|::...|...||..|||||| |...||. .|
  Fly    78 LLGHDIDFGHMEAVNLLSSNKYSEKQIGYLFISVLVNTNSDLIRLIIQSIKNDL-QSRNPVHVNL 141

  Rat   122 ALCTLSTMGSAEMCRDLATEVEKLF--QQPSPYVRKKAILAAVHMIRKDPEL-------SNIFLP 177
            ||..::.:||.:|....:.|:.||.  ......|::.|.|..:.:.|..|::       |.|.
  Fly   142 ALQCIANIGSRDMAESFSNEIPKLLVSGDTMDVVKQSAALCLLRLFRSSPDIIPGGEWTSRII-- 204

  Rat   178 PCTKLLRERHHGTLLGTITLITELCERNPAALRHFRKVVPQLVQILRTLVTTGYS--TEHSISGV 240
               .||.::|.|.:....:||..|.:|||   ..::..|...|..|..:||..|:  .:::...|
  Fly   205 ---HLLNDQHMGVVTAATSLIDALVKRNP---DEYKGCVNLAVSRLSRIVTASYTDLQDYTYYFV 263

  Rat   241 SDPFLQVQILRLLRILGRNHEES------SETMNDLLAQVATNTDTSR----NAGNAVLLETVLT 295
            ..|:|.|::||||:......||:      :||:..:|.:......:.:    ||.||||.|.:..
  Fly   264 PAPWLSVKLLRLLQNYNPVTEEAGVRARLNETLETILNKAQEPPKSKKVQHSNAKNAVLFEAINL 328

  Rat   296 IMAIHSAAGLRVLAVNILGRFLLNNDKNIRYVALTSLLQLVQSD--HSAVQRHRSTVVECLQ-EK 357
            |:...|...|.|.|.|.||:||.|.:.|:||:||.|:..|..|:  |..|::|:..|:..:: ||
  Fly   329 IIHSDSEPNLLVRACNQLGQFLSNRETNLRYLALESMCHLATSEFSHEEVKKHQEVVILSMKMEK 393

  Rat   358 DASLSRRALELSLALVNSSNVRAMMQELQAFLESCPPDLRADCASGILLAAERFAPSKRWHIDTI 422
            |.|:.:.|::|..|:.:..|...::||:..:||:....:|.:....:.:.||::|....|::|.|
  Fly   394 DVSVRQMAVDLLYAMCDRGNAEEIVQEMLNYLETADYSIREEMVLKVAILAEKYATDYTWYVDVI 458

  Rat   423 LHVLTTAGTHVRDDAVANLTQLIGEAEELHTYSVRRLYSALAEDISQQPLVQVAAWCIGEYGDLL 487
            |:::..||.:|.::....:.|::...||:..|:.:.::.||......:.:|:|..:.:||:|: |
  Fly   459 LNLIRIAGDYVSEEVWYRVIQIVINREEVQGYAAKTVFEALQAPACHENMVKVGGYILGEFGN-L 522

  Rat   488 LEGNCEETEPFQVEEEDVLALLEKVLQS--HMSLPATRGYAITALMKLSTRLQGDNNRIRQVVSI 550
            :.|:.......|.          |:|.|  |:..|.||...::..:|...........|:.|...
  Fly   523 IAGDSRSAPLVQF----------KLLHSKYHLCSPMTRALLLSTYIKFINLFPEIRTNIQDVFRQ 577

  Rat   551 YGS--CMDIELQQRAVEY---------NVLFQKYDHMRAAILEKMPLVERSDPQVNEEGKEKQTG 604
            :.:  ..|.||||||.||         :||        |.:||:||.....:..:....|:|:.|
  Fly   578 HSNLRSADAELQQRASEYLQLSIVASTDVL--------ATVLEEMPSFPERESSILAVLKKKKPG 634

  Rat   605 AQP----LEATAPVP 615
            ..|    .|:.:|.|
  Fly   635 RVPENEIRESKSPAP 649

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ap1g2	XP_002728326.1	Adaptin_N	23..574	CDD:279882	173/593 (29%)
		Alpha_adaptinC2	672..780	CDD:197886
AP-2alpha	NP_995607.1	Adaptin_N	40..598	CDD:279882	170/577 (29%)
		Alpha_adaptinC2	730..839	CDD:197886
		Alpha_adaptin_C	839..947	CDD:280460

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG4354
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53727
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820