| Sequence 1: | XP_011521103.1 | Gene: | CDH5 / 1003 | HGNCID: | 1764 | Length: | 793 | Species: | Homo sapiens |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_001036368.2 | Gene: | CadN2 / 35071 | FlyBaseID: | FBgn0262018 | Length: | 1799 | Species: | Drosophila melanogaster |
| Alignment Length: | 837 | Identity: | 216/837 - (25%) |
|---|---|---|---|
| Similarity: | 349/837 - (41%) | Gaps: | 194/837 - (23%) |
- Green bases have known domain annotations that are detailed below.
|
Human 33 RDTHSLLPTHRRQKRDWIWNQMHIDEEKNTSLPHHVGKIKSS---VSRK-NAKYLLKGEYV---- 89
Human 90 --GKVFRVDAETGDVFAIERLDRENIS---EYHLTAVIVDKDTGENLETPSSFTIKVHDVNDNWP 149
Human 150 VFTHRLFNASVPESSAVGTSVISVTAVDADDPTVGDHASVMYQILK-------GKEYFAID-NSG 206
Human 207 RIITITKSLDREKQARYEIVVEARDAQGLRGDSGTATVLVTLQDINDNFPFFTQTLWGALFASAK 271
Human 272 YTFVVPEDTRVGTSVGSLFVEDPDEPQNRMTKYSILRGDYQDAFTIETNPAHNEGIIKPMKPLDY 336
Human 337 EYIQQ---YSFIVEATDPTIDLRYMSPPAGN------RAQVIINITDV-DEPPIFQQPFYHFQLK 391
Human 392 ENQKKPLIGTVL----AMDPDAARHS-IGYSIRRTSDKGQFFRVTKKGDIYNEKELDREVYPWYN 451
Human 452 LTVEAKELDSTGTPTGKESIVQVHIEVLDENDNAPEFAKPYQPKVCENAVHGQLVLQISAIDKD- 515
Human 516 ---------------ITPRNVKFKFILNTENNFTLTDNHDNTANITVKYGQFDREHTKVHFLPVV 565
Human 566 ISDNGMPSRTGTSTLTVAVCKCNEQGEFTFCEDMAAQVGVSIQAVVAILLCILTITVITLLIFLR 630
Human 631 RRLRKQARAHGKSVPEIHEQLVTYDEEGGGE---------MDTTSYDVSVLNSVRRGGAKPPRPA 686
Human 687 LDARPSLYAQVQKPPRHAPGAHGGPGEMAA-------MIEVKKDEADHDGDGPPYD---TLHIYG 741
Human 742 YEGSESIAESLSSLGTDSSDSDVDYDFLNDWGP-----------RFK-MLAELYGSD 786 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| CDH5 | XP_011521103.1 | CA | 79..149 | CDD:214520 | 21/78 (27%) |
| Cadherin_repeat | 156..254 | CDD:206637 | 39/105 (37%) | ||
| Cadherin | 272..373 | CDD:278457 | 27/109 (25%) | ||
| Cadherin_repeat | 386..484 | CDD:206637 | 26/102 (25%) | ||
| Cadherin_repeat | 491..585 | CDD:206637 | 35/109 (32%) | ||
| Cadherin_C | 635..786 | CDD:307269 | 34/181 (19%) | ||
| CadN2 | NP_001036368.2 | Cadherin_repeat | 41..132 | CDD:206637 | 2/4 (50%) |
| Cadherin_repeat | 140..248 | CDD:206637 | 26/113 (23%) | ||
| Cadherin_repeat | 256..359 | CDD:206637 | 38/105 (36%) | ||
| Cadherin_repeat | 379..481 | CDD:206637 | 28/113 (25%) | ||
| Cadherin_repeat | 489..586 | CDD:206637 | 26/103 (25%) | ||
| Cadherin_repeat | 594..703 | CDD:206637 | 36/122 (30%) | ||
| Cadherin_repeat | 724..801 | CDD:206637 | 15/102 (15%) | ||
| EGF_CA | 977..1010 | CDD:238011 | |||
| LamG | 1013..1198 | CDD:238058 | |||
| EGF_2 | <1233..1259 | CDD:285248 | |||
| Laminin_G_2 | 1293..1428 | CDD:280389 | |||
| EGF_CA | 1497..1535 | CDD:238011 | |||
| Cadherin_C | 1583..1719 | CDD:279398 | |||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 1 | 1.000 | 69 | 1.000 | Domainoid score | I9605 |
| eggNOG | 0 | 0.000 | Not matched by this tool. | |||
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 1 | 1.100 | - | - | O | PTHR24027 |
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 3 | 3.010 | |||||