| Sequence 1: | NP_001280727.1 | Gene: | DUX4 / 100288687 | HGNCID: | 50800 | Length: | 424 | Species: | Homo sapiens |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_611756.1 | Gene: | CG9876 / 37668 | FlyBaseID: | FBgn0034821 | Length: | 275 | Species: | Drosophila melanogaster |
| Alignment Length: | 137 | Identity: | 45/137 - (32%) |
|---|---|---|---|
| Similarity: | 56/137 - (40%) | Gaps: | 33/137 - (24%) |
- Green bases have known domain annotations that are detailed below.
|
Human 83 RPWPGRRGPPEG--------RRKRTAVTGSQTALLLRAFEKDRFPGIAAREELARETGLPESRIQ 139
Human 140 IWFQNRRAR----HPGQGGRAPAQAGGLCSAAPGGGHPAP------SWVAFAHTGAWGTGLPAPH 194
Human 195 VPCAPGA 201 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| DUX4 | NP_001280727.1 | Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1..24 | ||
| homeodomain | 25..78 | CDD:238039 | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 72..102 | 9/26 (35%) | |||
| Homeodomain | 95..149 | CDD:459649 | 25/57 (44%) | ||
| PRK07764 | <141..319 | CDD:236090 | 22/71 (31%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 218..362 | ||||
| Required for interaction with EP300 and CREBBP, and for transcriptional activation of target genes. /evidence=ECO:0000269|PubMed:26951377 | 327..424 | ||||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 388..414 | ||||
| Important for transcriptional activation of target genes. /evidence=ECO:0000269|PubMed:29618456 | 405..424 | ||||
| CG9876 | NP_611756.1 | Homeodomain | 118..174 | CDD:459649 | 25/55 (45%) |
| Blue background indicates that the domain is not in the aligned region. | |||||