Protein Alignment limk2 and LIMK1

DIOPT Version :9

• Sequence 1: NP_001135686.1
• Gene: limk2 / 100216249
• XenbaseID: XB-GENE-976145
• Length: 606
• Species: Xenopus tropicalis
• Sequence 2: NP_511139.2
• Gene: LIMK1 / 32207
• FlyBaseID: FBgn0283712
• Length: 1257
• Species: Drosophila melanogaster
• Alignment Length: 646
• Identity: 255/646 - (39%)
• Similarity: 353/646 - (54%)
• Gaps: 107/646 - (16%)

 Frog    60 EQCLSCSLRLTGPAMVVSHYKFHPECFSCSGCKAMIGEGESFSLVQGTALYCGPCQKLLLLQPKF 124
            :.|..|...:|||.||...:|||||||.|:.|.:.||||||::||:.:.||||.|......||..
  Fly    93 DACQQCMAVITGPVMVAGEHKFHPECFCCTACGSFIGEGESYALVERSKLYCGQCYGKRSCQPAD 157

 Frog   125 EGLCIESAQEHDPHMLTLLRLPPQA-GGNRGFSVSREN---------------MQVTQVSTE--- 170
            ....|.:|.: ..|.:.|:.:|..| .|.|...|:.::               :.:|.::.:
  Fly   158 AKARITTAGK-PMHSIRLVEIPKDATPGLRVDGVALDDGCPTVRITDLFCNFFLWLTSMAEQCCG 221

 Frog   171 -------NLNLLHQGDRILEINGSPVTTLSSKEADDLLCSTDRTLQLLIEHNPP------PNLPV 222
                   ||..||.||||||:||:||:..|.::.|.|:.|.::.|||.:||:|.      ....:
  Fly   222 APYRIDVNLTNLHIGDRILEVNGTPVSDSSVEQIDKLIRSNEKMLQLTVEHDPVQVCRSCSQADI 286

 Frog   223 DNAP-------PKSPSFRSIEA-------RGSTEGPMKRSSIRRSNSNTRSPGTC---------- 263
            ..|.       |.|.|..|:|.       ....:|...|...:.:|::|..|...
  Fly   287 QRAMSASTLILPLSTSASSVEVGRERLYKTPGEQGTKARKLRQATNASTTIPPAAGATAMTQLKE 351

 Frog   264 ---CPK----------------DPR--SVSRSESLRCGVGGAQQIFRPCELLHGEELGKGFFGRA 307
               |..                .|:  .:||::|.|. |...|:|||..:|:.||:||:||||:.
  Fly   352 KERCSSLSKLLDEQHQAQQHSAHPQLYDLSRTQSCRV-VQKPQRIFRATDLVIGEKLGEGFFGKV 415

 Frog   308 IKVTHRATGRVMVMKELIQFDEQTQKNFLTEVKVMRSLDHPNVLRFIGVLYKDGRLNLLTEFIEC 372
            .|||||.:|.|||:|||.:.||:.|:||:.||.|:|.|||.:||:||||||||.:|:::||::..
  Fly   416 FKVTHRQSGEVMVLKELHRADEEAQRNFIKEVAVLRLLDHRHVLKFIGVLYKDKKLHMVTEYVAG 480

 Frog   373 GTLKDYLR--ADYCPWQQKVSFAKDIACGMAYLHSMSIIHRDLNSHNCLIKLDGTTVVADFGLSR 435
            |.||:.:.  |...||.|:|..|:||||||:|||||:||||||||.|||::.|.:.:||||||:|
  Fly   481 GCLKELIHDPAQVLPWPQRVRLARDIACGMSYLHSMNIIHRDLNSMNCLVREDRSVIVADFGLAR 545

 Frog   436 LIVEEKPLPA-------------PDRPPTKKRTLRKN---NRKKRYTVVGNPYWMAPEMLNGKDY 484
             .|:...||:             .|.|.:...|||::   .|::|||||||||||||||:.|..|
  Fly   546 -SVDAPRLPSGNMTPGGYGSGANSDAPMSPSGTLRRSKSRQRRQRYTVVGNPYWMAPEMMKGLKY 609

 Frog   485 DEKVDIFSFGIVLCEIIGQVYADPDCLPRTLDFGLNVRLFWEKFVPKDCPPGFFPLATSCCHLEP 549
            |||||:|||||:||||||:|.||||.:||..||.||.:.|.|||..: ||..|..:|..||.|.|
  Fly   610 DEKVDVFSFGIMLCEIIGRVEADPDFMPRNSDFSLNQQEFREKFCAQ-CPEPFVKVAFVCCDLNP 673

 Frog   550 DQRPDFPHLHDALTALSLFVGELGIP---LPSELE-YMEHSLQLEYGLN----REFSKLEE 602
            |.||.|..||..|..|:..:....:|   |..|:| :.|.....|..|:    |..:.|:|
  Fly   674 DMRPCFETLHVWLQRLADDLAADRVPPERLLHEIETFQEWYASSEDALSPTSQRSLNNLDE 734

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
limk2	NP_001135686.1	LIM2_LIMK	62..115	CDD:188751	28/52 (54%)
		STYKc	296..562	CDD:214568	155/283 (55%)
		STKc_LIMK2	299..568	CDD:271124	155/286 (54%)
LIMK1	NP_511139.2	LIM1_LIMK	33..88	CDD:188750
		LIM2_LIMK	95..148	CDD:188751	28/52 (54%)
		PDZ_signaling	172..271	CDD:238492	28/98 (29%)
		STKc_LIMK	407..693	CDD:271056	155/287 (54%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	309	1.000	Domainoid score	I1325
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D119463at33208
OrthoFinder	1	1.000	-	-		FOG0003618
OrthoInspector	1	1.000	-	-		otm48706
Panther	1	1.100	-	-	LDO	PTHR46485
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X2495
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	7.110