Protein Alignment csk and Src42A

DIOPT Version :9

• Sequence 1: NP_001135615.1
• Gene: csk / 100216174
• XenbaseID: XB-GENE-5771921
• Length: 450
• Species: Xenopus tropicalis
• Sequence 2: NP_610191.2
• Gene: Src42A / 35524
• FlyBaseID: FBgn0264959
• Length: 1597
• Species: Drosophila melanogaster
• Alignment Length: 463
• Identity: 174/463 - (37%)
• Similarity: 253/463 - (54%)
• Gaps: 70/463 - (15%)

 Frog     1 MSVV-QAPWQAGTECIANYDF----QGKAEQDLHFSKGEVLTIVAVTKDPNWYKAKNKVGRVGFI 60
            :||: |:|  |.|:|......    :||:.:...|::||.|
  Fly  1167 LSVIDQSP--ATTKCFGKTSLTTAKKGKSRRLSEFTRGEFL------------------------ 1205

 Frog    61 PANYVQKREGVKSGTKLSLMPWFHGKITREQAERLLYPPET--GLFLVRESTNYPGDYTLCVSCE 123
                     ..||        |:..||.|.:||:.|..||.  |.||:|:|.:...||:|.|...
  Fly  1206 ---------NEKS--------WYFRKIKRIEAEKKLLLPENEHGAFLIRDSESRHNDYSLSVRDG 1253

 Frog   124 GKVEHYRI-IYSSGKLSIDEEEYFENLMQLVEHYTNDADGLCTNLMKP--KLVEGTVAAQDEFSR 185
            ..|:|||| ....|...|.....|..|.:|||||:.|:||||.||.||  ::.:.........:|
  Fly  1254 DTVKHYRIRQLDEGGFFIARRTTFRTLQELVEHYSKDSDGLCVNLCKPCVQIEKPVTEGLSHRTR 1318

 Frog   186 SGWALKMRDLKLLHTIGKGEFGDVMLG-EHQGVKVAVKCIKNDA-TAQAFVAEAMVMTQLQHNNL 248
            ..|.:....||.:..:|.|:||||..| .:....||:|.:|:.. ..:.|:|||.:|.:|:|..|
  Fly  1319 DQWEIDRTSLKFVRKLGSGQFGDVWEGLWNNTTPVAIKTLKSGTMDPKDFLAEAQIMKKLRHTKL 1383

 Frog   249 VQLLGVIVEDKSGLFIVTEFMAKGSLVDYLRS---RGRSVLGGECLLKFSLDVSEGMAYLESNNF 310
            :||..|...::. ::|:||.|..|||::||::   :||| |..:.|:..:..::.|||||||.|:
  Fly  1384 IQLYAVCTVEEP-IYIITELMKHGSLLEYLQAIAGKGRS-LKMQTLIDMAAQIAAGMAYLESQNY 1446

 Frog   311 VHRDLAARNVLVSEENIAKVSDFGLTK-------EASAIQDTSKLPVKWTAPEALRDKLFSTKSD 368
            :|||||||||||.:.||.|::||||.:       ||..   .::.|:|||||||.....||.|||
  Fly  1447 IHRDLAARNVLVGDGNIVKIADFGLARLIKEDEYEARV---GARFPIKWTAPEAANYSKFSIKSD 1508

 Frog   369 VWSFGILLWEIYSFGRVPYPRIALKDVVPKVENGYKMDAPDGCPPVVYDLMKQCWHLDPKQRPTF 433
            ||||||||.|:.::||:|||.:...:|:.:||:||:|..|..|.|.:|::|.:|||.||.:||||
  Fly  1509 VWSFGILLTELVTYGRIPYPGMTNAEVLTQVEHGYRMPQPPNCEPRLYEIMLECWHKDPMRRPTF 1573

 Frog   434 RNLREQLE 441
            ..|:.:||
  Fly  1574 ETLQWKLE 1581

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
csk	NP_001135615.1	SH3_CSK	11..67	CDD:212703	8/59 (14%)
		SH2_csk_like	78..175	CDD:198190	41/101 (41%)
		PKc_like	188..443	CDD:389743	117/266 (44%)
Src42A	NP_610191.2	SH2_Src_Src42	1210..1301	CDD:198233	39/90 (43%)
		PTKc_Frk_like	1319..1587	CDD:270653	117/268 (44%)
		Pkinase_Tyr	1328..1580	CDD:285015	114/256 (45%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000006
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910