DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment hbs1l and eEF1alpha1

DIOPT Version :9

Sequence 1:	XP_012818243.1	Gene:	hbs1l / 100170572	XenbaseID:	XB-GENE-944105	Length:	677	Species:	Xenopus tropicalis
Sequence 2:	NP_001286321.1	Gene:	eEF1alpha1 / 36271	FlyBaseID:	FBgn0284245	Length:	463	Species:	Drosophila melanogaster

Alignment Length:	456	Identity:	166/456 - (36%)
Similarity:	259/456 - (56%)	Gaps:	32/456 - (7%)

- Green bases have known domain annotations that are detailed below.

Frog   235 KQKINIKEELEKRQGGKHLLNLVVIGHVDAGKSTLMGHLLYLLGHVNKRTMHKYEQESKKAGKAS 299
            |:||:|              |:|||||||:||||..|||:|..|.::|||:.|:|:|:::.||.|
  Fly     3 KEKIHI--------------NIVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAQEMGKGS 53

Frog   300 FAYAWVLDETGEERQRGVTMDVGMTKFETKSKVITLMDAPGHKDFIPNMITGAAQADVAVLAVDA 364
            |.||||||:...||:||:|:|:.:.||||....:|::|||||:|||.|||||.:|||.|||.|.|
  Fly    54 FKYAWVLDKLKAERERGITIDIALWKFETAKYYVTIIDAPGHRDFIKNMITGTSQADCAVLIVAA 118

Frog   365 SRGEFEAGFEAGGQTREHALLVRSLGVTQLAVAVNKMD--QVNWQQERFNEVTSKLGHFLKQAGF 427
            ..||||||....|||||||||..:|||.||.|.|||||  :..:.:.|:.|:..::..::|:.|:
  Fly   119 GTGEFEAGISKNGQTREHALLAFTLGVKQLIVGVNKMDSSEPPYSEARYEEIKKEVSSYIKKIGY 183

Frog   428 KESDVYYIPTSGLSGENLVKRSQISELINWYK------------GPCLLEQIDYFKAPQRSVDKP 480
            ..:.|.::|.||..|:|::   :.|..:.|:|            |..|::.:|....|.|..||.
  Fly   184 NPAAVAFVPISGWHGDNML---EPSTNMPWFKGWKVERKEGNADGKTLIDALDAILPPARPTDKA 245

Frog   481 FRLCTSDVFKDQGSGFCVTGKIEAGFVQTGDRLLAMPPHETCTVKGITLHEEAVDWAAAGDHVSL 545
            .||...||:|..|.|....|::|.|.::.|..::..|.:.|..||.:.:|.||:..|..||:|..
  Fly   246 LRLPLQDVYKIGGIGTVPVGRVETGVLKPGTVVVFAPANITTEVKSVEMHHEALQEAVPGDNVGF 310

Frog   546 TLTGMDIIKINVGCVF-CSPNEPIKACTRFRARVLIFNFEVPITQGFPVLIHYQTVSEPATIRKL 609
            .:..:.:.::..|.|. .|...|.|....|.|:|::.|....|..|:..::...|........::
  Fly   311 NVKNVSVKELRRGYVAGDSKANPPKGAADFTAQVIVLNHPGQIANGYTPVLDCHTAHIACKFAEI 375

Frog   610 VSVLHKSTGEVMKKKPKCLTKGMNAVIELQTQRPIALELYKDFKELGRFMLRYSGSSIAAGVVTE 674
            ...:.:.:|:..::.||.:..|..|::.|...:|:.:|.:::|..||||.:|....::|.||:..
  Fly   376 KEKVDRRSGKTTEENPKFIKSGDAAIVNLVPSKPLCVEAFQEFPPLGRFAVRDMRQTVAVGVIKA 440

Frog   675 I 675
            :
  Fly   441 V 441

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
hbs1l	XP_012818243.1	HBS1_N	<69..118	CDD:370196
hbs1l	XP_012818243.1	TEF1	254..677	CDD:227581	162/437 (37%)
eEF1alpha1	NP_001286321.1	PTZ00141	1..457	CDD:185474	166/456 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1150082at2759
OrthoFinder	1	1.000	-	-		FOG0000314
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.920