DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment PDCD6 and Pdcd6

DIOPT Version :9

Sequence 1:	NP_037364.1	Gene:	PDCD6 / 10016	HGNCID:	8765	Length:	191	Species:	Homo sapiens
Sequence 2:	NP_035181.1	Gene:	Pdcd6 / 18570	MGIID:	109283	Length:	191	Species:	Mus musculus

Alignment Length:	191	Identity:	189/191 - (98%)
Similarity:	189/191 - (98%)	Gaps:	0/191 - (0%)

- Green bases have known domain annotations that are detailed below.

Human     1 MAAYSYRPGPGAGPGPAAGAALPDQSFLWNVFQRVDKDRSGVISDTELQQALSNGTWTPFNPVTV 65
            |||||||||||.|||||||||||||||||||||||||||||||||.|||||||||||||||||||
Mouse     1 MAAYSYRPGPGGGPGPAAGAALPDQSFLWNVFQRVDKDRSGVISDNELQQALSNGTWTPFNPVTV 65

Human    66 RSIISMFDRENKAGVNFSEFTGVWKYITDWQNVFRTYDRDNSGMIDKNELKQALSGFGYRLSDQF 130
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Mouse    66 RSIISMFDRENKAGVNFSEFTGVWKYITDWQNVFRTYDRDNSGMIDKNELKQALSGFGYRLSDQF 130

Human   131 HDILIRKFDRQGRGQIAFDDFIQGCIVLQRLTDIFRRYDTDQDGWIQVSYEQYLSMVFSIV 191
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Mouse   131 HDILIRKFDRQGRGQIAFDDFIQGCIVLQRLTDIFRRYDTDQDGWIQVSYEQYLSMVFSIV 191

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
PDCD6	NP_037364.1	EFh_PEF_ALG-2	27..191	CDD:320058	162/163 (99%)
Pdcd6	NP_035181.1	EFh_PEF_ALG-2	27..191	CDD:320058	162/163 (99%)
		EF-hand motif	27..56	CDD:320058	27/28 (96%)
		EF-hand motif	64..93	CDD:320058	28/28 (100%)
		EF-hand motif	94..123	CDD:320058	28/28 (100%)
		EF-hand motif	130..159	CDD:320058	28/28 (100%)
		EF-hand motif	161..189	CDD:320058	27/27 (100%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C83964634
Domainoid	1	1.000	128	1.000	Domainoid score	I38717
eggNOG	1	0.900	-	-		E1_KOG0037
HGNC	1	1.500	-	-
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H7880
Inparanoid	1	1.050	393	1.000	Inparanoid score	I13791
Isobase	0	0.000	Not matched by this tool.
NCBI	1	1.000	-	-
OMA	1	1.010	-	-		QHG54126
OrthoDB	1	1.010	-	-		D1330600at2759
OrthoFinder	1	1.000	-	-		FOG0000697
OrthoInspector	1	1.000	-	-		oto112372
orthoMCL	1	0.900	-	-		OOG6_100410
Panther	1	1.100	-	-	LDO	PTHR23064
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4200
SonicParanoid	1	1.000	-	-		X1327
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	18	18.300