DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ptpn9 and Ptp61F

DIOPT Version :9

Sequence 1:	XP_012821586.2	Gene:	ptpn9 / 100158581	XenbaseID:	XB-GENE-967840	Length:	569	Species:	Xenopus tropicalis
Sequence 2:	NP_476687.1	Gene:	Ptp61F / 38160	FlyBaseID:	FBgn0267487	Length:	548	Species:	Drosophila melanogaster

Alignment Length:	305	Identity:	103/305 - (33%)
Similarity:	151/305 - (49%)	Gaps:	22/305 - (7%)

- Green bases have known domain annotations that are detailed below.

Frog   267 SGSVHRPGARGMTLAQLKEYVGRVGRRGTYEEYEEMRKKQPEGTFTVSLAP--VNRDRNRYGDVL 329
            |||.....||....|:.|: .|....|...|..|...::..|..|:.|.:.  .||..|||.||.
  Fly     7 SGSGSAAAARLQIEAEYKD-KGPQWHRFYKEICETCDREAKEKQFSTSESERHTNRGLNRYRDVN 70

Frog   330 CLDQTRVKLKRLNWHERSDYINASFMDGYLQKNMYIGTQGPLEKTFSDFWQMIWEQNVLVIVMTT 394
            ..|.:|:.|||    ...|||||:.:.....:..||.|||||..|...||.|:|||....::|..
  Fly    71 PYDHSRIVLKR----GSVDYINANLVQLERAERQYILTQGPLVDTVGHFWLMVWEQKSRAVLMLN 131

Frog   395 RVEEGGHRKCGQYWPLSTGSLST----YGAVTVTNKATENYQHYRKTTLELSTRQGKDKRLISHL 455
            ::.|....||..|||...|:...    :..:||.....|.||::.:...:|:..:.:..|.:...
  Fly   132 KLMEKKQIKCHLYWPNEMGADKALKLPHVKLTVELVRLETYQNFVRRWFKLTDLETQQSREVMQF 196

Frog   456 QFLSWPDFGVPSSASALINFRGAVKKEQRRLVEELGTQWRGPPGGPPFVVHCSAGIGRTGTFCTL 520
            .:.:|||||:|||.:|.:.|...| ::...|..::|          |.||||||||||:||||.:
  Fly   197 HYTTWPDFGIPSSPNAFLKFLQQV-RDSGCLSRDVG----------PAVVHCSAGIGRSGTFCLV 250

Frog   521 DICLSQLDDVGTVSIQETVQKMRQQRAFSIQTPEQYYFCYTSILE 565
            |.||..:|..|..::.:.:.::|..|...|||.:|..|.|.:|:|
  Fly   251 DCCLVLIDKYGECNVSKVLCELRSYRMGLIQTADQLDFSYQAIIE 295

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ptpn9	XP_012821586.2	CRAL_TRIO_N	10..58	CDD:215024
		SEC14	80..234	CDD:214706
		PTPc-N9	291..561	CDD:350391	92/275 (33%)
Ptp61F	NP_476687.1	PTPc	34..295	CDD:214550	93/275 (34%)
Ptp61F	NP_476687.1	PTPc	62..295	CDD:238006	86/247 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000704
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	2.000