DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment arhgap11a.1 and cv-c

DIOPT Version :9

Sequence 1:	NP_001121463.1	Gene:	arhgap11a.1 / 100158559	XenbaseID:	XB-GENE-1010876	Length:	946	Species:	Xenopus tropicalis
Sequence 2:	NP_001097786.1	Gene:	cv-c / 41749	FlyBaseID:	FBgn0285955	Length:	2351	Species:	Drosophila melanogaster

Alignment Length:	234	Identity:	75/234 - (32%)
Similarity:	110/234 - (47%)	Gaps:	25/234 - (10%)

- Green bases have known domain annotations that are detailed below.

Frog     8 RGLAKLAVVQHL-RSCGIKIKNWNSKQRPELGKATAQVLL----SGKVFGTPLHSLPYQYLPEYG 67
            |.||.:.:..|: |.|......||.    ||.|...::.:    ..||||.||    ...|...|
  Fly  1853 RKLALVTLTGHMERYCPSHRSGWNW----ELPKFIKKIKMPDYKDKKVFGVPL----LMILQRSG 1909

Frog    68 -NVPVILVIVCKSLEKH-LNTEGLFRKSGSVARQKLLKTKI---DNGENCLTT---ALPCDVAGI 124
             .:|:.:....:.|:.: |:..|:|||||..:|...|:.:|   |:...|:..   ....|||.:
  Fly  1910 QTLPLAVRAAFRWLQLNALDQVGIFRKSGGKSRIMKLREQIEVTDSTAECMDVFDLQQAYDVADM 1974

Frog   125 LKQFFRELPEPVLPTDLQDAFYKA-QHLSTDSERISATMLLTCLIPERTVQILQYFFSFLHAVAL 188
            |||:||||||.:|.|.:.:.|... |||..: .|:.|......|:|:...:||.....||..||.
  Fly  1975 LKQYFRELPESLLTTKMSETFVAIFQHLPAE-VRLDAVQCAVLLLPDENREILYVLLEFLTIVAA 2038

Frog   189 RSDANKMNSNNLAVIFAPNLLHS--NDDGEKISPSTEKK 225
            .|..|:|.||||.|..|.::.||  :.....:|.|..:|
  Fly  2039 NSQQNQMTSNNLGVCLAQSIFHSSISTGSASVSASPRRK 2077

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
arhgap11a.1	NP_001121463.1	RhoGAP-ARHGAP11A	50..250	CDD:239859	63/187 (34%)
cv-c	NP_001097786.1	SAM_DLC1,2-like	1382..1441	CDD:188937
		RhoGAP_DLC1	1893..2116	CDD:239840	64/190 (34%)
		SRPBCC	2148..2343	CDD:301327
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910