DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment pak5 and Pak

DIOPT Version :9

Sequence 1:	NP_001120110.1	Gene:	pak5 / 100145129	XenbaseID:	XB-GENE-960008	Length:	349	Species:	Xenopus tropicalis
Sequence 2:	NP_001138013.2	Gene:	Pak / 44039	FlyBaseID:	FBgn0267698	Length:	840	Species:	Drosophila melanogaster

Alignment Length:	375	Identity:	73/375 - (19%)
Similarity:	121/375 - (32%)	Gaps:	115/375 - (30%)

- Green bases have known domain annotations that are detailed below.

Frog     4 KKKKKL----------------DISGPSNFEHRVHTGFDHKEQKFIGLPQQWQSLLADT-ANRPK 51
            :|||.|                :||.|:||||.||.|||....:|.|:|:.|..||.:: .::.:
  Fly    60 RKKKTLKSKIKGSKPSHTDSKPNISYPTNFEHTVHVGFDAVTGEFTGMPEAWARLLMNSNISKQE 124

Frog    52 PMVDPSCITPIQLAPMKTIVRGSKP-PQDTYINGLLEDFDNISVTRSNSLRKESPPTPRLGHSNH 115
            ...:|..:..:    :|.....:|. |...|:...:......|::|.:|....|.||....|.::
  Fly   125 QKKNPQAVLDV----LKWFDNTTKQRPSSKYMTNAITTHSGSSLSRVSSSSPSSTPTDSELHGSN 185

Frog   116 LKGY------------PEENGFFAFSQYSCEPEVQRSNISERYKERS--LSAEEAEVYYRANKPV 166
            ..|.            |..|......|.          :...|:::.  |..::..:.::
  Fly   186 SGGNLIGVQLGSMTLGPNANNVAVAGQI----------LGNHYQQQQQHLLQQQQPLLHQ----- 235

Frog   167 RHNGHPVKMRSYETYFPEVKSVRADLSSYPS--------EYHPQLETKSKSVDQYDYHSIAGTSL 223
            .||.|.:.:....:|.....:|.:..|.:.|        ..|||.:..
  Fly   236 NHNQHHMGISQSHSYNFVGHTVSSSTSQHSSANEDDMLGPQHPQQQPP----------------- 283

Frog   224 QDYRDYFPPSITGTIMLSEGSRERLEYSEWGEGLPKDDYD----KRPKSSYITQTSPQPAMRQRS 284
                   ||.:.     |...|.:..|:.     |.:|..    ..|.:...|..:|    .|..
  Fly   284 -------PPPVA-----SRPERTKSIYTR-----PIEDLQPAIIPMPVAPATTPATP----LQNH 327

Frog   285 RSGSGLQEPIIPYGAGVM----------KTNQQGHPFSSYTYPRLSETGG 324
            |:..|:..|    .|..|          |......|.|..|....:||.|
  Fly   328 RTPGGISAP----AASPMMHNNATTTLDKNKNNATPTSPTTTKTTAETEG 373

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
pak5	NP_001120110.1	CRIB_PAK_like	11..55	CDD:238526	18/44 (41%)
Pak	NP_001138013.2	PBD	83..137	CDD:279166	19/57 (33%)
		STKc_PAK_I	558..818	CDD:270814
		S_TKc	566..817	CDD:214567
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D757766at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010