Protein Alignment rnf139 and hrd1

DIOPT Version :9

• Sequence 1: NP_001116520.1
• Gene: rnf139 / 100144552
• ZFINID: ZDB-GENE-080401-4
• Length: 664
• Species: Danio rerio
• Sequence 2: NP_596376.1
• Gene: hrd1 / 2539900
• PomBaseID: SPBC17D11.02c
• Length: 677
• Species: Schizosaccharomyces pombe
• Alignment Length: 547
• Identity: 111/547 - (20%)
• Similarity: 173/547 - (31%)
• Gaps: 233/547 - (42%)

Zfish    71 FKFYTLFMAVLLGAASVLVNYYATAHADFYSAYNSAAVLPRDGPTLWLALALMQLLLGLGYVALL 135
            |..|.|...||.| .|||::.|::|:.  |||            |:.::.:.:.:.:||
pombe     3 FILYVLASLVLFG-LSVLLSLYSSANV--YSA------------TVMISQSPVHITIGL------ 46

Zfish   136 RVRSVCAALLLLDIMAPLWGLILELPADMKQVLAIASGVILATHAALNLLL--KLKWFYYSCRYV 198
               :||..|.                      .|||:        ||..||  .|:.|
pombe    47 ---NVCLCLF----------------------FAIAN--------ALKTLLFGSLQTF------- 71

Zfish   199 YLLLRHMYRIYGLQLLLEDTWKRIRFPDILRVFWLTRVTAQAVILLYVVRVVRSESGMQLGWDVL 263
                       .|:||.|.             ||:|  ..:.::.:.|.|...|.|...|
pombe    72 -----------ELELLYEQ-------------FWIT--LTEIMLAITVFREAISISFFML----- 105

Zfish   264 WDLSSNLIISGCDSTLTVLGMSAVISSLAHYLGLSILAFIGSTEEEDKRLGFVAPVLFFILALQT 328
                           |:.|..:.|..|:..:          .||.                 ||.
pombe   106 ---------------LSTLMFARVFHSICSF----------RTER-----------------LQI 128

Zfish   329 GLSGLDPEERLVRLSRNMCLLLTAILHFIHGMTDPVLMSL--SASHVSSVRRHVPVLLV---SLV 388
            .|:    ::|....||..|      .:|:..:.|..|:.|  ::.|:..  :...:|.|   |::
pombe   129 QLT----DQRFHIFSRLTC------AYFVLSILDASLIYLCFTSEHLGD--KSTRMLFVCEFSVL 181

Zfish   389 LFTLPVLLSFLLWHHYAL----------NTWLFAVTAFCIELCLKVLVSLTVYALFMMDGFYNVL 443
            |..|.:..|.|..:.|..          :|:||.     :|:|...|..|....|||....|
pombe   182 LLNLTIEASKLCIYLYEARHLDQVWDEKSTYLFR-----LEVCRDGLRLLAYSLLFMYQFPY--- 238

Zfish   444 WEKLDDYVYYVRSTGNVIEFIFGVIMFGNGAYTMMFESGSKIRACMMCLHAYFNIYLQAKNGWKT 508
               :...:|.:|.                 .||..:....:||.     ||.|
pombe   239 ---VSVPIYSIRQ-----------------MYTCFYSLFRRIRE-----HARF------------ 266

Zfish   509 FINRRTAVKKINSL-PEVRGSRLRDIEDVCAICYQE--------------------FGSSARITP 552
                |.|.:.:|:: |.....:|.:.:..|.||.:|                    ...:.:..|
pombe   267 ----RQATRDMNAMYPTATEEQLTNSDRTCTICREEMFHPDHPPENTDEMEPLPRGLDMTPKRLP 327

Zfish   553 CSHYFHALCLRKWLYIQDTCPMCHQRV 579
            |.|..|..|||.||..|.|||:|.:.|
pombe   328 CGHILHFHCLRNWLERQQTCPICRRSV 354

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
rnf139	NP_001116520.1	TRC8_N	13..506	CDD:290425	87/451 (19%)
		zf-rbx1	516..576	CDD:289448	20/80 (25%)
		RING	537..579	CDD:238093	18/61 (30%)
hrd1	NP_596376.1	HRD1	1..514	CDD:227568	111/547 (20%)
		zf-RING_2	291..351	CDD:290367	17/59 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R6571
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.940