Protein Alignment FOXO6 and Foxo6

DIOPT Version :10

• Sequence 1: NP_001278210.2
• Gene: FOXO6 / 100132074
• HGNCID: 24814
• Length: 559
• Species: Homo sapiens
• Sequence 2: XP_038967150.1
• Gene: Foxo6 / 313558
• RGDID: 1595858
• Length: 582
• Species: Rattus norvegicus
• Alignment Length: 582
• Identity: 535/582 - (91%)
• Similarity: 544/582 - (93%)
• Gaps: 23/582 - (3%)

Human     1 MAAKLRAHQVDVDPDFAPQSRPRSCTWPLPQPDLAGDEDGALGAGVAEGAEDCGPERRATAPAMA 65
            |||||||||||||||||||||||||||||||||||||||||||||||||:|||||||||||||||
  Rat     1 MAAKLRAHQVDVDPDFAPQSRPRSCTWPLPQPDLAGDEDGALGAGVAEGSEDCGPERRATAPAMA 65

Human    66 PAPPLGAEVGPLRKAKSSRRNAWGNLSYADLITKAIESAPDKRLTLSQIYDWMVRYVPYFKDKGD 130
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Rat    66 PAPPLGAEVGPLRKAKSSRRNAWGNLSYADLITKAIESAPDKRLTLSQIYDWMVRYVPYFKDKGD 130

Human   131 SNSSAGWK-----------------------NSIRHNLSLHTRFIRVQNEGTGKSSWWMLNPEGG 172
            ||||||||                       ||||||||||||||||||||||||||||||||||
  Rat   131 SNSSAGWKAFPQRVNSPLYLQLHFKDTKLKQNSIRHNLSLHTRFIRVQNEGTGKSSWWMLNPEGG 195

Human   173 KTGKTPRRRAVSMDNGAKFLRIKGKASKKKQLQAPERSPDDSSPSAPAPGPVPAAAKWAASPASH 237
            ||||||||||||||||||||||||||||||||..||||||||.|.||||||:.|:||||||||||
  Rat   196 KTGKTPRRRAVSMDNGAKFLRIKGKASKKKQLHLPERSPDDSPPGAPAPGPMSASAKWAASPASH 260

Human   238 ASDDYEAWADFRGGGRPLLGEAAELEDDEALEALAPSSPLMYPSPASALSPALGSRCPGELPRLA 302
            |||||||||||||.||||||||||||||||||||||||||||||||||||||||:||||||||||
  Rat   261 ASDDYEAWADFRGSGRPLLGEAAELEDDEALEALAPSSPLMYPSPASALSPALGARCPGELPRLA 325

Human   303 ELGGPLGLHGGGGAGLPEGLLDGAQDAYGPRARAGTPAYFGGCKGGAYGGGGGFGPPAMGALRRL 367
            ||||||||||||.||||:.||||||||||||||||||:||||||..||||||||||||:|:||||
  Rat   326 ELGGPLGLHGGGVAGLPDALLDGAQDAYGPRARAGTPSYFGGCKASAYGGGGGFGPPALGSLRRL 390

Human   368 PMQTIQENKQASFVPAAAPFRPGALPALLPPPPPAPRPGPVLGAPGELALAGAAAAYPGKGAAPY 432
            |||||||||||||.||||||||||||||||||||||||||:||||||||||||||||||||||||
  Rat   391 PMQTIQENKQASFAPAAAPFRPGALPALLPPPPPAPRPGPLLGAPGELALAGAAAAYPGKGAAPY 455

Human   433 APPAPSRSALAHPISLMTLPGEAGAAGLAPSGHAAAFGGPPGGLLLDALPGPYAAAAAGPLGAAP 497
            ||||||||||||||||||||||||||||||..||.||||||||||||||||||||||||||||.|
  Rat   456 APPAPSRSALAHPISLMTLPGEAGAAGLAPPAHATAFGGPPGGLLLDALPGPYAAAAAGPLGAGP 520

Human   498 DRFPADLDLDMFSGSLECDVESIILNDFMDSDEMDFNFDSALPPPPPGLAGAPPPNQSWVPG 559
            ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Rat   521 DRFPADLDLDMFSGSLECDVESIILNDFMDSDEMDFNFDSALPPPPPGLAGAPPPNQSWVPG 582

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
FOXO6	NP_001278210.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..76		73/74 (99%)
		FH_FOXO6	89..176	CDD:410837	86/109 (79%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	163..235		64/71 (90%)
		FOXO_KIX_bdg	358..>382	CDD:465228	21/23 (91%)
		FOXO-TAD	499..537	CDD:435506	37/37 (100%)
Foxo6	XP_038967150.1	FH_FOX	89..199	CDD:469596	86/109 (79%)
		FOXO_KIX_bdg	381..>400	CDD:465228	16/18 (89%)
		FOXO-TAD	522..560	CDD:435506	37/37 (100%)