| Sequence 1: | NP_001308154.1 | Gene: | HDAC6 / 10013 | HGNCID: | 14064 | Length: | 1229 | Species: | Homo sapiens |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_001259569.1 | Gene: | HDAC6 / 32461 | FlyBaseID: | FBgn0026428 | Length: | 1179 | Species: | Drosophila melanogaster |
| Alignment Length: | 1276 | Identity: | 473/1276 - (37%) |
|---|---|---|---|
| Similarity: | 651/1276 - (51%) | Gaps: | 259/1276 - (20%) |
- Green bases have known domain annotations that are detailed below.
|
Human 8 RGQASSTMTSTGQDSTTTRQRRSRQNPQSPPQDSSVTSKRNIKKGAVPR--SIPN--LAEVKKKG 68
Human 69 K---MKKLGQAMEEDLIVGLQGMDLNLEAEALAGTGLVLDEQLNEFHCLWDDSFPEGPERLHAIK 130
Human 131 EQLIQEGLLDRCVSFQARFAEKEELMLVHSLEYID-LMETTQYMNEGELRVLADTYDSVYLHPNS 194
Human 195 YSCACLASGSVLRLVDAVLGAEIRNGMAIIRPPGHHAQHSLMDGYCMFNHVAVAARYAQQKHRIR 259
Human 260 RVLIVDWDVHHGQGTQFTFDQDPSVLYFSIHRYEQGRFWPHLKASNWSTTGFGQGQGYTINVPWN 324
Human 325 QVGMRDADYIAAFLHVLLPVALEFQPQLVLVAAGFDALQGDPKGEMAATPAGFAQLTHLLMGLAG 389
Human 390 GKLILSLEGGYNLRALAEGVSASLHTLLGDPC-PMLESPGAP-CRSAQASVSCALEALEPFWEVL 452
Human 453 -VRST----ETVERDNMEED--NVEESEEEGPWEPPV---------LPI----LT-----WPVLQ 492
Human 493 SRTGL---------VYDQNMMNHCNLWDSHHPEVPQRILRIMCRLEELGLAGRCLTLTPRPATEA 548
Human 549 ELLTCHSAEYVGHLRATEKMKTRELHRESSNFDSIYICPSTFACAQLATGAACRLVEAVLSGEVL 613
Human 614 NGAAVVRPPGHHAEQDAACGFCFFNSVAVAARHAQTISGHAL-RILIVDWDVHHGNGTQHMFEDD 677
Human 678 PSVLYVSLHRYDHGTFFPMGDEGASSQIGRAAGTGFTVNVAWNGPRMGDADYLAAWHRLVLPIAY 742
Human 743 EFNPELVLVSAGFDAARGDPLGGCQVSPEGYAHLTHLLMGLASGRIILILEGGYNLTSISESMAA 807
Human 808 CTRSLLGDPPP-----LLTLPRPP---LSGALASITETIQVHRRYWRSLRVMKVEDREGPSSSKL 864
Human 865 VTKKAPQPAKPRLAERMTTREKKVLEAGMGKVTSASFGEESTPGQTNSETAVVALTQDQPSEAAT 929
Human 930 GGATLAQTISEAAIGGAMLGQTTSEEAVGGATPDQTTSEETVGGAILDQTTSEDAVGGATLGQTT 994
Human 995 SEEAVGGATLAQTTSEAAMEGATLDQTTSEEAPGGTELIQTPLASSTDHQTPPTSPVQGTTPQIS 1059
Human 1060 PSTLIGSLRTLELGSESQGASESQAPGEENLLGEAAGGQDMADSMLMQGSRGLTDQAIFYAVTPL 1124
Human 1125 PWCPHLVAVCPIPA-AGLDVTQPCGDCGTIQENWVCLSCYQVYCGRYINGHMLQHHGNSGHPLVL 1188
Human 1189 SYIDLSAWCYYCQAYVHHQALLDVKNIAHQNKFGEDMPHPH 1229 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| HDAC6 | NP_001308154.1 | HDAC6-dom1 | 113..449 | CDD:212545 | 159/338 (47%) |
| HDAC6-dom2 | 499..849 | CDD:212527 | 186/358 (52%) | ||
| zf-UBP | 1147..1209 | CDD:280334 | 36/61 (59%) | ||
| HDAC6 | NP_001259569.1 | HDAC10_HDAC6-dom1 | 119..457 | CDD:212526 | 158/340 (46%) |
| HDAC6-dom2 | 538..895 | CDD:212527 | 174/365 (48%) | ||
| zf-UBP | 1007..1069 | CDD:280334 | 4/61 (7%) |
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 1 | 0.930 | - | - | C165158097 | |
| Domainoid | 1 | 1.000 | 327 | 1.000 | Domainoid score | I1170 |
| eggNOG | 1 | 0.900 | - | - | E1_COG0123 | |
| Hieranoid | 1 | 1.000 | - | - | ||
| Homologene | 1 | 1.000 | - | - | H31353 | |
| Inparanoid | 1 | 1.050 | 805 | 1.000 | Inparanoid score | I497 |
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 1 | 1.010 | - | - | QHG45835 | |
| OrthoDB | 1 | 1.010 | - | - | D1484694at2759 | |
| OrthoFinder | 1 | 1.000 | - | - | FOG0001161 | |
| OrthoInspector | 1 | 1.000 | - | - | oto89674 | |
| orthoMCL | 1 | 0.900 | - | - | OOG6_100220 | |
| Panther | 1 | 1.100 | - | - | LDO | PTHR48252 |
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 1 | 1.030 | - | avgDist | Average_Evolutionary_Distance | R2991 |
| SonicParanoid | 1 | 1.000 | - | - | X2174 | |
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 1 | 0.960 | - | - | ||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 16 | 15.800 | |||||