Protein Alignment rnf145l and Rnf145

DIOPT Version :10

• Sequence 1: NP_001106467.1
• Gene: rnf145l / 100127651
• XenbaseID: XB-GENE-5921670
• Length: 679
• Species: Xenopus tropicalis
• Sequence 2: NP_001099248.1
• Gene: Rnf145 / 287212
• RGDID: 1309561
• Length: 664
• Species: Rattus norvegicus
• Alignment Length: 666
• Identity: 350/666 - (52%)
• Similarity: 465/666 - (69%)
• Gaps: 20/666 - (3%)

 Frog     3 RLEEIANVVLRLPSVVVLDLLYRWDFQA-FTELSRPTYETN-FFKSKYL-WNIYYLAHVLCAVLL 64
            :||.:.||.||:||:::||:|||||..: |.::.|.:...| .|:.||| .|::|:.::|..|||
  Rat     6 KLEAVLNVALRVPSIMLLDVLYRWDVSSFFQQIQRSSLSNNPLFQYKYLALNMHYVGYILSVVLL 70

 Frog    65 LLPLRYLVSIYLYLLTALLLYVGHQTTRDYIHQEMDSDFPGALFEDQGALSRIITALTGLVIVGT 129
            .||.::||.:|||.|||||||.|||.:|||:..|::|.:.|.::.:..:::|..|||.|.::|.|
  Rat    71 TLPRQHLVQLYLYFLTALLLYAGHQISRDYVRSELESAYEGPMYLEPLSMNRFTTALIGQLVVCT 135

 Frog   130 LCSLLMKTRHAWLFCSPVLPLLGRIVGLPLQALPPLNNFSIFLTVLGSLFYVLSNLGVLLILFRK 194
            |||.:|||:..|||.:.:||||.|:..:||:.:..:|.|::..|.|..|:::.|||.|...|.:.
  Rat   136 LCSCVMKTKQIWLFSAHMLPLLARLCLVPLETIVIINKFAMIFTGLEVLYFLGSNLLVPYNLAKS 200

 Frog   195 VYQEIVQVQELDRVVALVMQLWTHLAVPLLFLVFWLVSFSFHIVSFLSSKPGALGQQGLIFIFLN 259
            .|:|:|||.|:..::||.|.||..|.||:||:|||||.|:..|.|:.|::.....::.|:|:||.
  Rat   201 AYRELVQVVEVYGLLALGMSLWNQLVVPVLFMVFWLVLFALQIYSYFSTRDQPASRERLLFLFLT 265

 Frog   260 SAAECCGTPYCLIGLTFTVSYLALGMLNFCKFYLLGFDAFRNGNVMHRGVTEGVTLMLLALQTGL 324
            |.||||.|||.|:||.||||::|||:|..|||||.|:.||.|...|:||:||||||::||:||||
  Rat   266 SIAECCSTPYSLLGLVFTVSFVALGVLTLCKFYLQGYRAFMNDPAMNRGMTEGVTLLILAVQTGL 330

 Frog   325 LDLQVLQRTFLLSIILFIVVTSTLQSMIEIADPIVLALGATRNRSLWKHLRGVSMCLFLLVFPCF 389
            ::|||:.|.|||||||||||.|.||||:||||||||||||:|::|||||.|.||:||||||||.:
  Rat   331 IELQVVHRAFLLSIILFIVVASILQSMLEIADPIVLALGASRDKSLWKHFRAVSLCLFLLVFPAY 395

 Frog   390 MAYKISQFFHMDFWLLILVSSCMLTSLQVLGTLFIYALFMVELFHDSQVEKIDEIIYYVNAVSRV 454
            |||.|.|||||||||||::||.:|||||||||||||.|||||.|....||.:|::|||||...|:
  Rat   396 MAYMICQFFHMDFWLLIIISSSILTSLQVLGTLFIYVLFMVEEFRKEPVENMDDVIYYVNGTYRL 460

 Frog   455 LEFLVAVCVVAYGTWESLFGEWSWMGVSVIIVHSYFNVWLRAQSGWKSFLLRREAAKKISSLPMA 519
            ||||||:||||||..|::||||:.||..:|.:|||:|||||||.|||||||||:|..||.|||:|
  Rat   461 LEFLVALCVVAYGVSETIFGEWTVMGSMIIFIHSYYNVWLRAQLGWKSFLLRRDAVNKIKSLPIA 525

 Frog   520 TLEQLRAHNDVCPICFQDMSGAVITPCSHIFHGECLRKWLYVQDTCPICHQQVKPLAETLREGEE 584
            |.|||..|||:|.||:|||..||||||||.||..||:||||||||||:||..:|..::....|.|
  Rat   526 TKEQLERHNDICAICYQDMKSAVITPCSHFFHAGCLKKWLYVQDTCPLCHCHLKNSSQLPGLGTE 590

 Frog   585 KSEEEEEVEADEEVRAEVTAHGFRRNQCNPERGREEMELGEDRRDQTNGGE---RRCDAKHEREE 646
            .:.:.....|::.:   |...|       ||....|...|...::.:....   .|..|..|
  Rat   591 PAPQPPVAGAEQNI---VLQEG-------PEPPDHETPPGPGAQEGSGDNSEYINRSSASRE--- 642

 Frog   647 VEEEDEGENSASGGGE 662
             .:.|.|:......||
  Rat   643 -GDADPGDGPQIAEGE 657

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
rnf145l	NP_001106467.1	TRC8_N	5..500	CDD:463960	279/497 (56%)
		RING-H2_RNF139-like	529..569	CDD:438139	29/39 (74%)
Rnf145	NP_001099248.1	TRC8_N	8..506	CDD:463960	279/497 (56%)
		HRD1	<520..643	CDD:227568	54/136 (40%)
		RING-H2_RNF145	533..575	CDD:319598	31/41 (76%)