DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment rnf145l and SPCC548.05c

DIOPT Version :9

Sequence 1:	NP_001106467.1	Gene:	rnf145l / 100127651	XenbaseID:	XB-GENE-5921670	Length:	679	Species:	Xenopus tropicalis
Sequence 2:	NP_587745.1	Gene:	SPCC548.05c / 2539314	PomBaseID:	SPCC548.05c	Length:	468	Species:	Schizosaccharomyces pombe

Alignment Length:	241	Identity:	56/241 - (23%)
Similarity:	79/241 - (32%)	Gaps:	90/241 - (37%)

- Green bases have known domain annotations that are detailed below.

Frog   508 EAAKKISSLPMATLEQLRAHNDVCPICFQDMSGAVITPCSHIFHGECLRKWLYVQDTCPICHQQV 572
            |..:||..    |||        ||||.:.:.....|.|.|.:..|||..||....:||.|.|::
pombe    74 ETFQKIKK----TLE--------CPICTEALQRPFTTHCGHTYCYECLLNWLKESKSCPTCRQKL 126

Frog   573 ----------------------------------KPLAETLREGEEKSEEEEE-----VEADEEV 598
                                              |...|.|.:|..|.|:...     |::::.|
pombe   127 YTQPSPAYLVYEIMNVVAASNSGFPLVGINENPAKKQKEVLFDGMFKQEDSHYPRSILVDSEDGV 191

Frog   599 --------RAEVTAH----GFRRNQCNPERGREEMELGEDRR-------DQTNGGERRCDAKHER 644
                    ..|...|    ||:.:. :.:.|||....||:..       |.|.||....:.....
pombe   192 LRCARCQWELENPYHCDHCGFQISD-DQDSGREWFWDGENAESDSSLNGDNTRGGNISTNRAFNN 255

Frog   645 ------EEVEEE----DEGENSASGGGEGSHLE----GVGQVEVTD 676
                  ..|.::    ||||...     ||.||    |.|:.:|.|
pombe   256 MGHAPITAVPQDWLRFDEGEEFV-----GSDLESDFSGPGEYDVDD 296

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rnf145l	NP_001106467.1	TRC8_N	5..500	CDD:290425
		zf-rbx1	<528..569	CDD:289448	14/40 (35%)
		zf-RING_2	529..569	CDD:290367	14/39 (36%)
SPCC548.05c	NP_587745.1	RING	84..126	CDD:238093	17/49 (35%)
SPCC548.05c	NP_587745.1	COG2888	<193..213	CDD:268082	3/19 (16%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910