Protein Alignment rnf145l and RNF145

DIOPT Version :9

• Sequence 1: NP_001106467.1
• Gene: rnf145l / 100127651
• XenbaseID: XB-GENE-5921670
• Length: 679
• Species: Xenopus tropicalis
• Sequence 2: NP_001186309.1
• Gene: RNF145 / 153830
• HGNCID: 20853
• Length: 693
• Species: Homo sapiens
• Alignment Length: 660
• Identity: 352/660 - (53%)
• Similarity: 461/660 - (69%)
• Gaps: 18/660 - (2%)

 Frog     3 RLEEIANVVLRLPSVVVLDLLYRWDFQA-FTELSRPTYETN-FFKSKYL-WNIYYLAHVLCAVLL 64
            :||.:.||.||:||:::||:|||||..: |.::.|.:...| .|:.||| .|::|:.::|..|||
Human    36 KLEAVLNVALRVPSIMLLDVLYRWDVSSFFQQIQRSSLSNNPLFQYKYLALNMHYVGYILSVVLL 100

 Frog    65 LLPLRYLVSIYLYLLTALLLYVGHQTTRDYIHQEMDSDFPGALFEDQGALSRIITALTGLVIVGT 129
            .||.::||.:|||.|||||||.|||.:|||:..|::..:.|.::.:..:::|..|||.|.::|.|
Human   101 TLPRQHLVQLYLYFLTALLLYAGHQISRDYVRSELEFAYEGPMYLEPLSMNRFTTALIGQLVVCT 165

 Frog   130 LCSLLMKTRHAWLFCSPVLPLLGRIVGLPLQALPPLNNFSIFLTVLGSLFYVLSNLGVLLILFRK 194
            |||.:|||:..|||.:.:||||.|:..:||:.:..:|.|::..|.|..|:::.|||.|...|.:.
Human   166 LCSCVMKTKQIWLFSAHMLPLLARLCLVPLETIVIINKFAMIFTGLEVLYFLGSNLLVPYNLAKS 230

 Frog   195 VYQEIVQVQELDRVVALVMQLWTHLAVPLLFLVFWLVSFSFHIVSFLSSKPGALGQQGLIFIFLN 259
            .|:|:|||.|:..::||.|.||..|.||:||:|||||.|:..|.|:.|::.....::.|:|:||.
Human   231 AYRELVQVVEVYGLLALGMSLWNQLVVPVLFMVFWLVLFALQIYSYFSTRDQPASRERLLFLFLT 295

 Frog   260 SAAECCGTPYCLIGLTFTVSYLALGMLNFCKFYLLGFDAFRNGNVMHRGVTEGVTLMLLALQTGL 324
            |.||||.|||.|:||.||||::|||:|..|||||.|:.||.|...|:||:||||||::||:||||
Human   296 SIAECCSTPYSLLGLVFTVSFVALGVLTLCKFYLQGYRAFMNDPAMNRGMTEGVTLLILAVQTGL 360

 Frog   325 LDLQVLQRTFLLSIILFIVVTSTLQSMIEIADPIVLALGATRNRSLWKHLRGVSMCLFLLVFPCF 389
            ::|||:.|.|||||||||||.|.||||:||||||||||||:|::|||||.|.||:||||||||.:
Human   361 IELQVVHRAFLLSIILFIVVASILQSMLEIADPIVLALGASRDKSLWKHFRAVSLCLFLLVFPAY 425

 Frog   390 MAYKISQFFHMDFWLLILVSSCMLTSLQVLGTLFIYALFMVELFHDSQVEKIDEIIYYVNAVSRV 454
            |||.|.|||||||||||::||.:|||||||||||||.|||||.|....||.:|::|||||...|:
Human   426 MAYMICQFFHMDFWLLIIISSSILTSLQVLGTLFIYVLFMVEEFRKEPVENMDDVIYYVNGTYRL 490

 Frog   455 LEFLVAVCVVAYGTWESLFGEWSWMGVSVIIVHSYFNVWLRAQSGWKSFLLRREAAKKISSLPMA 519
            ||||||:||||||..|::||||:.||..:|.:|||:|||||||.|||||||||:|..||.|||:|
Human   491 LEFLVALCVVAYGVSETIFGEWTVMGSMIIFIHSYYNVWLRAQLGWKSFLLRRDAVNKIKSLPIA 555

 Frog   520 TLEQLRAHNDVCPICFQDMSGAVITPCSHIFHGECLRKWLYVQDTCPICHQQVKPLAETLREGEE 584
            |.|||..|||:|.||:|||..||||||||.||..||:||||||:|||:||..:|..::....|.|
Human   556 TKEQLEKHNDICAICYQDMKSAVITPCSHFFHAGCLKKWLYVQETCPLCHCHLKNSSQLPGLGTE 620

 Frog   585 -----KSEEEEEVEADEEVRAEVTAH--GFRRNQCNPERGREEMELGEDRRDQTNGG----ERRC 638
                 .:..|:.|...|........|  |.|..    |..|:..|....|.|...|.    |...
Human   621 PVLQPHAGAEQNVMFQEGTEPPGQEHTPGTRIQ----EGSRDNNEYIARRPDNQEGAFDPKEYPH 681

 Frog   639 DAKHEREEVE 648
            .||.|...||
Human   682 SAKDEAHPVE 691

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
rnf145l	NP_001106467.1	TRC8_N	5..500	CDD:290425	278/497 (56%)
		zf-rbx1	<528..569	CDD:289448	29/40 (73%)
		zf-RING_2	529..569	CDD:290367	28/39 (72%)
RNF145	NP_001186309.1	TRC8_N	38..536	CDD:290425	278/497 (56%)
		zf-rbx1	<564..605	CDD:289448	29/40 (73%)
		zf-RING_2	565..605	CDD:290367	28/39 (72%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
NCBI	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG46488
OrthoDB	1	1.010	-	-		D119734at7742
OrthoFinder	1	1.000	-	-		FOG0006288
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X4575
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.930