Protein Alignment GNPDA1 and Pgls

DIOPT Version :10

• Sequence 1: XP_005268405.1
• Gene: GNPDA1 / 10007
• HGNCID: 4417
• Length: 318
• Species: Homo sapiens
• Sequence 2: NP_572656.1
• Gene: Pgls / 32013
• FlyBaseID: FBgn0030239
• Length: 243
• Species: Drosophila melanogaster
• Alignment Length: 239
• Identity: 59/239 - (24%)
• Similarity: 97/239 - (40%)
• Gaps: 63/239 - (26%)

Human    24 SQSKDKMKLI--------------ILEHYSQASEWAAKYIRNRIIQFNPGPEKYFTLGLPTGSTP 74
            |:.|..:|:|              :|:..||  |..||:.:             |::||..||
  Fly     2 SEKKGALKVIPSASEEQLVQALGDLLQRCSQ--EALAKHDK-------------FSVGLSGGS-- 49

Human    75 LGCYKKLIEYYKNGDL-SFKYVKTFNMDEYVGLPRDHPESYHSFM--WNNFFKHID----IHPEN 132
              ..:.|.:..|:.:| :.|:|..|..:.||.|. |...:|.::.  |......|.    :..:.
  Fly    50 --LVQLLTKALKSCNLKTAKWVFFFCDERYVRLD-DSDSTYGAYRAEWLTQLPCIQESQFVRADT 111

Human   133 THILDGNAVDLQAECDAFEEKIKA-AGGIELFVGGIGPDGHIA--FNEPGSSLVSRTRVKTLAMD 194
            :..||..|.|       :|.|:|: ....:|.:.|:|||||..  |.|..::|   ...|.|.:.
  Fly   112 SQPLDACAAD-------YEAKVKSQVDRFDLLLLGMGPDGHTCSLFPEQPATL---QETKRLVIP 166

Human   195 TILANARFFDGELTKVPTMALTVGVGTVMDAREVMILITGAHKA 238
              :.|:       .|.|...:|..:..:..||.|..::|||.||
  Fly   167 --IRNS-------PKPPPERITFTLPLINKARNVAFVVTGAAKA 201

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GNPDA1	XP_005268405.1	nagB	30..287	CDD:179028	57/233 (24%)
Pgls	NP_572656.1	Glucosamine_iso	14..228	CDD:460101	55/227 (24%)