Protein Alignment MED6 and MED6

DIOPT Version :9

• Sequence 1: NP_001271140.1
• Gene: MED6 / 10001
• HGNCID: 19970
• Length: 257
• Species: Homo sapiens
• Sequence 2: NP_001163577.1
• Gene: MED6 / 44728
• FlyBaseID: FBgn0024330
• Length: 249
• Species: Drosophila melanogaster
• Alignment Length: 254
• Identity: 114/254 - (44%)
• Similarity: 160/254 - (62%)
• Gaps: 15/254 - (5%)

Human     1 MAAVDIRDNLLGISWVDSSWIPILNSGSVLDYFSERSNPFYDRTCNNEVVKMQRLTLEHLNQMVG 65
            ||:..:.::.|.:||.|:..:..|:..:|:|||..:||||||..||||.|:||||..|||:.|:|
  Fly     1 MASRQMTNDHLRLSWHDTQMMATLSPQTVMDYFCRKSNPFYDHMCNNETVRMQRLGPEHLHNMIG 65

Human    66 IEYILLHAQEPILFIIRKQQRQSPAQVIPLADYYIIAGVIYQAPDLGSVINSRVLTAVHGIQSAF 130
            :||||||..||||::||||.|.:|::..|:||||||.|.:|:||||.:|||||:|..|..:||||
  Fly    66 LEYILLHVAEPILYVIRKQHRHNPSEATPIADYYIIGGTVYKAPDLANVINSRILNTVVNLQSAF 130

Human   131 DEAMSYCRYHPSKGYWWH------FKDHEEQDKVRPKAKRKEEPSSIFQRQRVDALLLDLRQKFP 189
            :||.||.||||:|||.|.      |.|..:.||....:.:.|...::||:||||.||.:|.:|||
  Fly   131 EEASSYARYHPNKGYTWDFSSNKVFSDRSKSDKKDANSAKDENSGTLFQKQRVDMLLAELLRKFP 195

Human   190 PKF-VQLKPGEKPVPVD---QTKKEAEPIPETVKPEEKETTKNVQQTVSAKGPPEKRMR 244
            |.. ..|:..::|.|..   .|.:.|..:.....|.:.:|     :.|..|.||||:.:
  Fly   196 PPIPPMLQNLQQPPPAGDDLNTARNASEMNNATGPLDIKT-----EGVDMKPPPEKKSK 249

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MED6	NP_001271140.1	Med6	13..139	CDD:282750	72/125 (58%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	193..246		13/55 (24%)
MED6	NP_001163577.1	Med6	13..139	CDD:282750	72/125 (58%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165153113
Domainoid	1	1.000	168	1.000	Domainoid score	I3842
eggNOG	1	0.900	-	-		E1_COG5097
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H3990
Inparanoid	1	1.050	222	1.000	Inparanoid score	I3546
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG55402
OrthoDB	1	1.010	-	-		D1251252at2759
OrthoFinder	1	1.000	-	-		FOG0005042
OrthoInspector	1	1.000	-	-		oto90679
orthoMCL	1	0.900	-	-		OOG6_102673
Panther	1	1.100	-	-	LDO	PTHR13104
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2638
SonicParanoid	1	1.000	-	-		X5378
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	17	16.800