DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment si:dkey-33c12.12 and SPAC23G3.12c

DIOPT Version :9

Sequence 1:	NP_001082916.2	Gene:	si:dkey-33c12.12 / 100000024	ZFINID:	ZDB-GENE-081028-30	Length:	214	Species:	Danio rerio
Sequence 2:	NP_593112.1	Gene:	SPAC23G3.12c / 2541812	PomBaseID:	SPAC23G3.12c	Length:	996	Species:	Schizosaccharomyces pombe

Alignment Length:	229	Identity:	53/229 - (23%)
Similarity:	102/229 - (44%)	Gaps:	47/229 - (20%)

- Green bases have known domain annotations that are detailed below.

Zfish     1 MGSPFSLKNTITSGIISSAQRGSK---ELGLSNSNMDYIQTDATIDFGNSGGPLINLDGEVIGIN 62
            :|:..:.|.:|.:|.||...|...   ||...:.|.:|||..|....|:||.|::..:|.|:.:.
pombe   167 VGNDAAEKLSILAGWISRIDRNVPDYGELTYCDFNTNYIQAAANASGGSSGSPVVERNGNVVALQ 231

Zfish    63 T-MKVTAGISFAIPLGR----VRL---------------FLDRSADKQKSWFGESGWKRRYIGVM 107
            . ..:.|...:.:||.|    :|.               ||.::.|:                ..
pombe   232 AGGHMIAATDYFLPLDRPLRALRCLQNNTPITRGTIQAQFLIKTFDE----------------CS 280

Zfish   108 MLTLTPSIIEELRMRDPSFPDISHGVLIHRVIVGSPANRAGMKPGDVIIEINGVKVNTSEEIYNA 172
            .|.|..::.|::|   ..||:.:..:::..|:...|:.:. :|.||:::.:|.:.:....|:.:.
pombe   281 RLGLDSAMEEKVR---TLFPEATSMLVVETVLPEGPSFKK-LKEGDILLYVNSMILINLIELESI 341

Zfish   173 VRTSESLNVV--VRRGADLLMLHMTPESTEGHQV 204
            :..|...:||  |:||::|:.|..|.:||  |.:
pombe   342 LDESVGKDVVLTVQRGSELVELTCTAQST--HDI 373

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
si:dkey-33c12.12	NP_001082916.2	Trypsin_2	<1..61	CDD:290102	20/62 (32%)
si:dkey-33c12.12	NP_001082916.2	PDZ_serine_protease	102..186	CDD:238487	17/85 (20%)
SPAC23G3.12c	NP_593112.1	DegQ	38..369	CDD:223343	50/221 (23%)
		Trypsin_2	84..230	CDD:290102	20/62 (32%)
		PDZ_serine_protease	289..365	CDD:238487	19/79 (24%)
		PDZ_1	372..448	CDD:289574	0/2 (0%)
		DegQ	<551..834	CDD:223343
		Tryp_SPc	551..698	CDD:304450
		PDZ	<779..834	CDD:294084
		PDZ	844..919	CDD:294084
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	42	1.000	Domainoid score	I4178
eggNOG	1	0.900	-	-		E1_COG0265
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	4	3.770